Stem-loop aae-mir-275

Accession

MI0013434

Description

Aedes aegypti aae-mir-275 precursor miRNA

Literature search

5 open access papers mention aae-mir-275
(156 sentences)

Sequence

680033 reads, 35700 reads per million, 2 experiments

auccuuucgauuucgCGCGCUAAGCAGGAACCGAGACuuugucauuugcuagcagUCAGGUACCUGAAGUAGCGCgcgugauc
........((((.(((((((((..((((.(((..(((((((........))).)))).))).))))...))))))))).))))

Structure

auccuuuc    u         -AG    A   GA    -   uca 
        gauu cgCGCGCUA   CAGG ACC  GACu uug   u
        |||| |||||||||   |||| |||  |||| |||    
        cuag gcgCGCGAU   GUCC UGG  CUga gau   u
--------    u         GAA    A   -A    c   cgu 

Annotation confidence High

Comments

This miRNA was identified independently in Aedes aegypti [1] and in the closely related Aedes albopictus, for which there was no genome sequence [2]. The latter reads were therefore also mapped to the Aedes aegypti genome [2].

Genome context

supercont1.24: 486536-486618 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from aae-mir-275

Mature aae-miR-275-5p

• Accession: MIMAT0014208
• Description: Aedes aegypti aae-miR-275-5p mature miRNA
• Sequence: 16 - CGCGCUAAGCAGGAACCGAGAC - 37
• Evidence: experimental ; 454 [1], Illumina [2]

Mature aae-miR-275-3p

• Accession: MIMAT0014209
• Description: Aedes aegypti aae-miR-275-3p mature miRNA
• Sequence: 56 - UCAGGUACCUGAAGUAGCGC - 75
• Evidence: experimental ; 454 [1], Illumina [2]

References

1. PubMed ID: 19961592
   Direct sequencing and expression analysis of a large number of miRNAs in Aedes aegypti and a multi-species survey of novel mosquito miRNAs
   Li S, Mead EA, Liang S, Tu Z
   BMC Genomics (2009) 10:581


2. PubMed ID: 20167119
   Identification of microRNAs expressed in two mosquito vectors, Aedes albopictus and Culex quinquefasciatus
   Skalsky RL, Vanlandingham DL, Scholle F, Higgs S, Cullen BR
   BMC Genomics (2010) 11:119