Stem-loop bma-let-7

Accession

MI0013319

Description

Brugia malayi bma-let-7 precursor miRNA

Literature search

27 open access papers mention bma-let-7
(168 sentences)

Sequence

82044 reads, 4162.0 reads per million, 26 experiments

augcuaacgacccugaaugauagcuugcucgaUGAGGUAGUAGGUUGUAUAGUUaugaguuguaccauaaucggagaaaCUGUCCAGCCUGCUAGCUUGCCgugcgggucuaucauccgucccc
........(((...((.(((((((((((.((.((((.((((((((((.(((((((((........)))).........))))).)))))))))).)))).)).))))).)))))))).)))...

Structure

augcuaac   ccu  a      -     u  a    G          U     ---------    agu 
        gac   ga ugauag cuugc cg UGAG UAGUAGGUUG AUAGU         Uaug   u
        |||   || |||||| ||||| || |||| |||||||||| |||||         ||||    
        cug   cu acuauc gggcg gC GUUC AUCGUCCGAC UGUCa         auac   g
-----ccc   --c  -      u     u  C    G          C     aagaggcua    cau 

Annotation confidence High

Genome context

Bmal_v3_scaffold247: 47896-48019 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from bma-let-7

Mature bma-let-7-5p

• Accession: MIMAT0014094
• Description: Brugia malayi bma-let-7-5p mature miRNA
• Sequence: 33 - UGAGGUAGUAGGUUGUAUAGUU - 54
• Evidence: experimental ; Northern [1], Illumina [2]

Mature bma-let-7-3p

• Accession: MIMAT0057199
• Description: Brugia malayi bma-let-7-3p mature miRNA
• Sequence: 80 - CUGUCCAGCCUGCUAGCUUGCC - 101
• Evidence: experimental ; Northern [1], Illumina [2]

References

1. PubMed ID: 19874857
   Cloning and bioinformatic identification of small RNAs in the filarial nematode, Brugia malayi
   "Poole CB, Davis PJ, Jin J, McReynolds LA"
   "Mol Biochem Parasitol (2010) 169:87-94


2. PubMed ID: 24824352
   Diversity and expression of microRNAs in the filarial parasite, Brugia malayi
   Poole CB, Gu W, Kumar S, Jin J, Davis PJ, Bauche D, McReynolds LA
   PLoS One (2014) 9:e96498