miRBase entry: ame-mir-34

Stem-loop ame-mir-34


Accession
MI0005739
Description
Apis mellifera ame-mir-34 precursor miRNA mir-34
Gene
family?
RF00456; mir-34

Summary
Caution, this is an AI generated summary based on literature. This may have errors. ?

Ame-mir-34 is a microRNA whose expression levels in the larval gut of 4-day-old larvae were quantified using the 2−ΔΔCt method [PMC9863880]. Although an upregulation of ame-mir-34 was observed in this developmental stage, comparative analysis revealed no significant difference when larvae were co-treated with A. apis and a mimic of miR-34 versus a control mimic [PMC9863880]. This suggests that ame-mir-34's expression might be influenced by additional factors that were not identified in this study [PMC9863880].

Literature search
7 open access papers mention ame-mir-34
(24 sentences)

Sequence

uuuuuuugcgauuggcauguUGGCAGUGUUGUUAGCUGGUUGuguggcuacauuguauauacgaccgcuaucggcacugcaauuaugacgaucguagggu
...(((((((((((.((((...(((((((((.((((.(((((((((((......)).))))))))))))).)))))))))...)))).))))))))))).

Structure
uuu           g    uUG         U    U         -  ua 
   uuuugcgauug caug   GCAGUGUUG UAGC GGUUGugug gc  c
   ||||||||||| ||||   ||||||||| |||| ||||||||| ||   
   gggaugcuagc guau   cgucacggc aucg ccagcauau ug  a
--u           a    uaa         u    -         a  uu 


Annotation confidence Not enough data
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Genome context
CM000058.5: 6962684-6962783 [+]
Clustered miRNAs
2 other miRNAs are < 10 kb from ame-mir-34
Name Accession Chromosome Start End Strand Confidence




Database links

Mature ame-miR-34-5p

Accession MIMAT0004430
Description Apis mellifera ame-miR-34-5p mature miRNA
Sequence 21 - UGGCAGUGUUGUUAGCUGGUUG - 42
Evidence experimental
Illumina [2]

References

  1. PubMed ID: 17543122
    Computational and transcriptional evidence for microRNAs in the honey bee genome
    Weaver DB, Anzola JM, Evans JD, Reid JG, Reese JT, Childs KL, Zdobnov EM, Samanta MP, Miller J, Elsik CG
    Genome Biol (2007) 8:R97

  2. PubMed ID: 22409512
    Behavioral plasticity in honey bees is associated with differences in brain microRNA transcriptome
    "Greenberg JK, Xia J, Zhou X, Thatcher SR, Gu X, Ament SA, Newman TC, Green PJ, Zhang W, Robinson GE, Ben-Shahar Y"
    "Genes Brain Behav (2012) 11:660-670