Stem-loop mmu-mir-511

Accession

MI0005554

Symbol

MGI: Mir511

Description

Mus musculus mmu-mir-511 precursor miRNA

Literature search

10 open access papers mention mmu-mir-511
(141 sentences)

Sequence

6262 reads, 53 reads per million, 81 experiments

gauacccaccAUGCCUUUUGCUCUGCACUCAguaaauaauaauuugugAAUGUGUAGCAAAAGACAGGAUggggaucca
((..((((((.((.((((((((.((((.(((.(((((....)))))))).)))).)))))))).)))).))))..))..

Structure

--  ua    -  A  C        C    C   g     a 
  ga  ccca cc UG CUUUUGCU UGCA UCA uaaau a
  ||  |||| || || |||||||| |||| ||| |||||  
  cu  gggU GG AC GAAAACGA GUGU Agu guuua u
ac  ag    A  -  A        U    A   -     a 

Annotation confidence High

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was independently shown in human and rat [2].

Genome context

chr2: 14261003-14261081 [+]

Mature mmu-miR-511-5p

• Accession: MIMAT0004940
• Description: Mus musculus mmu-miR-511-5p mature miRNA
• Sequence: 11 - AUGCCUUUUGCUCUGCACUCA - 31
• Evidence: experimental ; RAKE [1], Illumina [3-4]

Mature mmu-miR-511-3p

• Accession: MIMAT0017281
• Description: Mus musculus mmu-miR-511-3p mature miRNA
• Sequence: 49 - AAUGUGUAGCAAAAGACAGGAU - 70
• Evidence: experimental ; Illumina [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298