Stem-loop mmu-mir-877

Accession

MI0005553

Symbol

MGI: Mir877

Description

Mus musculus mmu-mir-877 precursor miRNA mir-877

Gene
family

RF00912; mir-877

Literature search

17 open access papers mention mmu-mir-877
(25 sentences)

Sequence

10471 reads, 35 reads per million, 102 experiments

GUAGAGGAGAUGGCGCAGGGgacacaagguaggccuugcgggucuguggacccuuggacaugUGUCCUCUUCUCCCUCCUCCCAg
...((((((..((.(.((((((((((..((...((....(((((....)))))..)))).)))))))))).).))))))))....

Structure

-GUA      AU  C C          ag  agg  uugc     u 
    GAGGAG  GG G AGGGgacaca  gu   cc    ggguc g
    ||||||  || | ||||||||||  ||   ||    |||||  
    CUCCUC  CC C UCUCCUGUgu  ca   gg    cccag u
gACC      --  U U          -a  ---  --uu     g 

Annotation confidence Not enough data

Comments

This sequence was identified as a miRNA candidate by Berezikov et al. using RAKE and MPSS techniques [1]. Expression was later confirmed by cloning [2].

Genome context

chr17: 35960730-35960814 [-]

Mature mmu-miR-877-5p

• Accession: MIMAT0004861
• Description: Mus musculus mmu-miR-877-5p mature miRNA
• Sequence: 1 - GUAGAGGAGAUGGCGCAGGG - 20
• Evidence: experimental ; cloned [1-2], Illumina [4-5]

Mature mmu-miR-877-3p

• Accession: MIMAT0004862
• Description: Mus musculus mmu-miR-877-3p mature miRNA
• Sequence: 63 - UGUCCUCUUCUCCCUCCUCCCA - 84
• Evidence: experimental ; cloned [1-2], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 16954537
   Many novel mammalian microRNA candidates identified by extensive cloning and RAKE analysis
   "Berezikov E, van Tetering G, Verheul M, van de Belt J, van Laake L, Vos J, Verloop R, van de Wetering M, Guryev V, Takada S, van Zonneveld AJ, Mano H, Plasterk R, Cuppen E"
   "Genome Res (2006) 16:1289-1298


5. PubMed ID: 17964270
   Mammalian mirtron genes
   "Berezikov E, Chung WJ, Willis J, Cuppen E, Lai EC"
   "Mol Cell (2007) 28:328-336