Stem-loop dre-mir-489

Accession

MI0003256

Description

Danio rerio dre-mir-489 precursor miRNA mir-489

Gene
family

RF00698; mir-489

Literature search

7 open access papers mention dre-mir-489
(7 sentences)

Sequence

207090 reads, 163.0 reads per million, 249 experiments

acugacuugagugguggccuggUGGUCGUAUGUAUGACGUCAUUuacuucaaaguuuggagUGACAUCAUAUGUACGGCUGCUaaacugcuacauggcucauca
.......(((((.(((((.((((((((((((((((((.((((((((((....)))...))))))).))))))))))))))))))....)))))...)))))...

Structure

acugacu     --g     ---c                  C       ---   u 
       ugagu   guggc    uggUGGUCGUAUGUAUGA GUCAUUu   acu c
       |||||   |||||    |||||||||||||||||| |||||||   |||  
       acucg   caucg    aUCGUCGGCAUGUAUACU CAGUgag   uga a
----acu     gua     ucaa                  A       guu   a 

Annotation confidence High

Comments

miR-489 was predicted in zebrafish based on homology with a verified mammalian sequence (Mihaela Zavolan, personal communication), and later verified experimentally [1].

Genome context

chr19: 40781168-40781271 [-]

Mature dre-miR-489-5p

• Accession: MIMAT0052784
• Description: Danio rerio dre-miR-489-5p mature miRNA
• Sequence: 23 - UGGUCGUAUGUAUGACGUCAUU - 44
• Evidence: experimental ; cloned [1], Northern [1]

Mature dre-miR-489-3p

• Accession: MIMAT0002940
• Description: Danio rerio dre-miR-489-3p mature miRNA
• Sequence: 62 - UGACAUCAUAUGUACGGCUGCU - 83
• Evidence: experimental ; cloned [1], Northern [1]

References

1. PubMed ID: 16698962
   Cloning and expression of new microRNAs from zebrafish
   "Kloosterman WP, Steiner FA, Berezikov E, de Bruijn E, van de Belt J, Verheul M, Cuppen E, Plasterk RH"
   "Nucleic Acids Res (2006) 34:2558-2569