Stem-loop mml-mir-20a

Accession

MI0003004

Description

Macaca mulatta mml-mir-20a precursor miRNA

Literature search

2 open access papers mention mml-mir-20a
(4 sentences)

Sequence

45808 reads, 486 reads per million, 8 experiments

guagcacUAAAGUGCUUAUAGUGCAGGUAguguuuaguuaucuACUGCAUUAUGAGCACUUAAAGUacugc
((((.(((.(((((((((((((((((.(((...........))))))))))))))))))))..))).))))

Structure

    c   -A                 G   uguu 
guag acU  AAGUGCUUAUAGUGCAG UAg    u
|||| |||  ||||||||||||||||| |||    a
cguc UGA  UUCACGAGUAUUACGUC Auc    g
    a   AA                 -   uauu 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr17: 73096567-73096637 [+]

Clustered miRNAs

5 other miRNAs are < 10 kb from mml-mir-20a

Mature mml-miR-20a-5p

• Accession: MIMAT0002704
• Description: Macaca mulatta mml-miR-20a-5p mature miRNA
• Sequence: 8 - UAAAGUGCUUAUAGUGCAGGUA - 29
• Evidence: experimental ; Illumina [2]

Mature mml-miR-20a-3p

• Accession: MIMAT0026597
• Description: Macaca mulatta mml-miR-20a-3p mature miRNA
• Sequence: 44 - ACUGCAUUAUGAGCACUUAAAGU - 66
• Evidence: experimental ; Illumina [2]

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


2. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45