Stem-loop ggo-mir-221

Accession

MI0002893

Description

Gorilla gorilla ggo-mir-221 precursor miRNA

Literature search

3 open access papers mention ggo-mir-221
(6 sentences)

Sequence

22672 reads, 1918.0 reads per million, 4 experiments

ugaacauccaggucuggggcaugaACCUGGCAUACAAUGUAGAUUUcuguguucguuaggcaacAGCUACAUUGUCUGCUGGGUUUcaggcuaccuggaaacauguucuc
.((((((((((((....(((.(((((((((((.(((((((((....(((((((.....))).))))))))))))).))))))).)))).))))))))))....)))))..

Structure

-u     ----       cugg   a    -       U         AUUU    -   c 
  gaaca    uccaggu    ggc ugaA CCUGGCA ACAAUGUAG    cugu guu g
  |||||    |||||||    ||| |||| ||||||| |||||||||    |||| ||| u
  cuugu    aggucca    ucg acUU GGGUCGU UGUUACAUC    GAca cgg u
cu     acaa       ----   g    U       C         ----    a   a 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chrX: 46266443-46266552 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from ggo-mir-221

Mature ggo-miR-221-5p

• Accession: MIMAT0061268
• Description: Gorilla gorilla ggo-miR-221-5p mature miRNA
• Sequence: 25 - ACCUGGCAUACAAUGUAGAUUU - 46
• Evidence: experimental

Mature ggo-miR-221-3p

• Accession: MIMAT0002584
• Description: Gorilla gorilla ggo-miR-221-3p mature miRNA
• Sequence: 65 - AGCUACAUUGUCUGCUGGGUUU - 86
• Evidence: not_experimental

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24