Stem-loop ptr-mir-127

Accession

MI0002583

Description

Pan troglodytes ptr-mir-127 precursor miRNA

Literature search

2 open access papers mention ptr-mir-127
(99 sentences)

Sequence

64492 reads, 527.0 reads per million, 24 experiments

ugugaucacugucuccagccugCUGAAGCUCAGAGGGCUCUGAUucagaaagaucaUCGGAUCCGUCUGAGCUUGGCUggucggaagucucaucauc
.(((((.(((...(((.(((.(((.(((((((((.((.((((((((.....))..)))))).)).)))))))))))).))).))))))...))))).

Structure

u     --c   guc   a   u   G         G  C      --  a 
 gugau   acu   ucc gcc gCU AAGCUCAGA GG UCUGAU  uc g
 |||||   |||   ||| ||| ||| ||||||||| || ||||||  || a
 uacua   uga   agg ugg CGG UUCGAGUCU CC AGGCUa  ag a
c     cuc   ---   c   U   -         G  U      cu  a 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [1]. The expression of the mature miRNA was not validated.

Genome context

chr14: 86127939-86128035 [+]

Clustered miRNAs

6 other miRNAs are < 10 kb from ptr-mir-127

Mature ptr-miR-127-5p

• Accession: MIMAT0052201
• Description: Pan troglodytes ptr-miR-127-5p mature miRNA
• Sequence: 23 - CUGAAGCUCAGAGGGCUCUGAU - 44
• Evidence: not_experimental

Mature ptr-miR-127-3p

• Accession: MIMAT0002282
• Description: Pan troglodytes ptr-miR-127-3p mature miRNA
• Sequence: 57 - UCGGAUCCGUCUGAGCUUGGCU - 78
• Evidence: not_experimental

References

1. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24