Stem-loop mml-mir-128a

Accession

MI0002518

Description

Macaca mulatta mml-mir-128a precursor miRNA mir-128

Gene
family

RF00649; mir-128

Sequence

79712 reads, 514 reads per million, 8 experiments

ugagcuguuggauuCGGGGCCGUAGCACUGUCUGAGAgguuuacauuucUCACAGUGAACCGGUCUCUUUUucagcugcuuc
.((((.((((((...(((((((...((((((..(((((((....)))))))))))))...)))))))...)))))).)))).

Structure

u    u      uuC       UAG      CU       u 
 gagc guugga   GGGGCCG   CACUGU  GAGAggu u
 |||| ||||||   |||||||   ||||||  |||||||  
 uucg cgacuU   CUCUGGC   GUGACA  CUcuuua a
c    u      UUU       CAA      --       c 

Annotation confidence High

Comments

Berezikov et al. used primers designed from human miRNA gene flanking sequence to amplify miRNA precursor regions in primates [2]. The expression of this mature miRNA was validated by Miska et al [1].

Genome context

chr12: 21159071-21159152 [+]

Mature mml-miR-128a-3p

• Accession: MIMAT0002229
• Description: Macaca mulatta mml-miR-128a-3p mature miRNA
• Sequence: 50 - UCACAGUGAACCGGUCUCUUUU - 71
• Evidence: experimental ; cloned [1], Illumina [3]

Mature mml-miR-128a-5p

• Accession: MIMAT0026565
• Description: Macaca mulatta mml-miR-128a-5p mature miRNA
• Sequence: 15 - CGGGGCCGUAGCACUGUCUGAGA - 37
• Evidence: experimental ; Illumina [3]

References

1. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68


2. PubMed ID: 15652478
   Phylogenetic shadowing and computational identification of human microRNA genes
   "Berezikov E, Guryev V, van de Belt J, Wienholds E, Plasterk RH, Cuppen E"
   "Cell (2005) 120:21-24


3. PubMed ID: 23034410
   Birth and expression evolution of mammalian microRNA genes
   "Meunier J, Lemoine F, Soumillon M, Liechti A, Weier M, Guschanski K, Hu H, Khaitovich P, Kaessmann H"
   "Genome Res (2013) 23:34-45