Stem-loop mmu-mir-425

Accession

MI0001447

Symbol

MGI: Mir425

Description

Mus musculus mmu-mir-425 precursor miRNA mir-425

Gene
family

RF00803; mir-425

Literature search

19 open access papers mention mmu-mir-425
(82 sentences)

Sequence

102140 reads, 495 reads per million, 104 experiments

aaagugcuuuggAAUGACACGAUCACUCCCGUUGAgugggcacccaagaagccAUCGGGAAUGUCGUGUCCGCCcagugcucuuu
((((.((.((((...(((((((.((.(((((....((((............))))))))).)))))))))...)))).)).))))

Structure

    u  u    AAU       U  C     UUGA    gcacc 
aaag gc uugg   GACACGA CA UCCCG    gugg     c
|||| || ||||   ||||||| || |||||    ||||      
uuuc cg gacC   CUGUGCU GU AGGGC    UAcc     a
    u  u    CGC       -  A     ----    gaaga 

Annotation confidence High

Genome context

chr9: 108568777-108568861 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-425

Mature mmu-miR-425-5p

• Accession: MIMAT0004750
• Description: Mus musculus mmu-miR-425-5p mature miRNA
• Sequence: 13 - AAUGACACGAUCACUCCCGUUGA - 35
• Evidence: experimental ; cloned [2], Illumina [3-4]

Mature mmu-miR-425-3p

• Accession: MIMAT0001342
• Description: Mus musculus mmu-miR-425-3p mature miRNA
• Sequence: 54 - AUCGGGAAUGUCGUGUCCGCC - 74
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009