Stem-loop rno-mir-145

Accession

MI0000918

Description

Rattus norvegicus rno-mir-145 precursor miRNA

Literature search

80 open access papers mention rno-mir-145
(703 sentences)

Sequence

1053674 reads, 807 reads per million, 484 experiments

caccuuguccucacgGUCCAGUUUUCCCAGGAAUCCCUuggaugcuaagauggGGAUUCCUGGAAAUACUGUUCuugaggucauggcu
..((.((.(((((.((..((((.((.((((((((((((.............)))))))))))).)).))))..))))))).)).))..

Structure

ca  u  u     c  UC    U  C            uggau 
  cc ug ccuca gG  CAGU UU CCAGGAAUCCCU     g
  || || ||||| ||  |||| || ||||||||||||     c
  gg ac ggagu uC  GUCA AA GGUCCUUAGGgg     u
uc  u  u     -  UU    U  A            uagaa 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3]. The ends of the miRNA may be offset with respect to previous annotations.

Genome context

chr18: 56969907-56969994 [-]

Clustered miRNAs

1 other miRNA is < 10 kb from rno-mir-145

Mature rno-miR-145-5p

• Accession: MIMAT0000851
• Description: Rattus norvegicus rno-miR-145-5p mature miRNA
• Sequence: 16 - GUCCAGUUUUCCCAGGAAUCCCU - 38
• Evidence: experimental ; cloned [1-3], SOLiD [4]

Mature rno-miR-145-3p

• Accession: MIMAT0017131
• Description: Rattus norvegicus rno-miR-145-3p mature miRNA
• Sequence: 54 - GGAUUCCUGGAAAUACUGUUC - 74
• Evidence: experimental ; SOLiD [4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249


4. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68