Stem-loop rno-mir-30b

Accession

MI0000868

Description

Rattus norvegicus rno-mir-30b precursor miRNA

Literature search

63 open access papers mention rno-mir-30b
(421 sentences)

Sequence

1144717 reads, 996 reads per million, 504 experiments

ccgaguuucaguucaUGUAAACAUCCUACACUCAGCUgucauacaugaguuggCUGGGAUGUGGAUGUUUACGUCagcugucuugga
(((((...(((((.((((((((((((.((((((((((.(((....)))...))))))).))))))))))))))).))))).))))).

Structure

-     uuu     c            U   -       --g   u 
 ccgag   caguu aUGUAAACAUCC ACA CUCAGCU   uca a
 |||||   ||||| |||||||||||| ||| |||||||   |||  
 gguuc   gucga UGCAUUUGUAGG UGU GGGUCgg   agu c
a     --u     C            -   A       uug   a 

Annotation confidence High

Comments

Landgraf et al. show that miRNA sequences from both arms of this hairpin precursor are similarly expressed [4].

Genome context

Unknown

Mature rno-miR-30b-5p

• Accession: MIMAT0000806
• Description: Rattus norvegicus rno-miR-30b-5p mature miRNA
• Sequence: 16 - UGUAAACAUCCUACACUCAGCU - 37
• Evidence: experimental ; cloned [1-4], Northern [1,3], SOLiD [5]

Mature rno-miR-30b-3p

• Accession: MIMAT0004721
• Description: Rattus norvegicus rno-miR-30b-3p mature miRNA
• Sequence: 54 - CUGGGAUGUGGAUGUUUACGUC - 75
• Evidence: experimental ; cloned [4], SOLiD [5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


3. PubMed ID: 14691248
   Identification of many microRNAs that copurify with polyribosomes in mammalian neurons
   "Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G"
   "Proc Natl Acad Sci U S A (2004) 101:360-365


4. PubMed ID: 20403161
   Small RNA expression and strain specificity in the rat
   Linsen SE, de Wit E, de Bruijn E, Cuppen E
   BMC Genomics (2010) 11:249


5. PubMed ID: 15345052
   Microarray analysis of microRNA expression in the developing mammalian brain
   Miska EA, Alvarez-Saavedra E, Townsend M, Yoshii A, Sestan N, Rakic P, Constantine-Paton M, Horvitz HR
   Genome Biol (2004) 5:R68