Stem-loop mmu-mir-365-1

Accession

MI0000768

Symbol

MGI: Mir365-1

Description

Mus musculus mmu-mir-365-1 precursor miRNA

Gene family

MIPF0000061; mir-365

Literature search

25 open access papers mention mmu-mir-365-1
(93 sentences)

Sequence

19968 reads, 353 reads per million, 105 experiments

accgcagggaaaaugAGGGACUUUUGGGGGCAGAUGUGuuuccauuccgcuaucaUAAUGCCCCUAAAAAUCCUUAUugcucuugca
...((((((..((((((((..(((((((((((..((((...............)))).))))))))))).))))))))..)))))).

Structure

acc      aa        AC           GA    uuucca 
   gcaggg  aaugAGGG  UUUUGGGGGCA  UGUG      u
   ||||||  ||||||||  |||||||||||  ||||      u
   cguucu  uUAUUCCU  AAAAUCCCCGU  AUac      c
--a      cg        -A           -A    uaucgc 

Annotation confidence High

Comments

Xie et al. [1] refer to this sequence by the internal identifier MIR245. The sequence is unrelated to C. elegans mir-245 (MIR:MI0000321).

Genome context

chr16: 13453840-13453926 [+]

Clustered miRNAs

1 other miRNA is < 10 kb from mmu-mir-365-1

Mature mmu-miR-365-1-5p

• Accession: MIMAT0017077
• Description: Mus musculus mmu-miR-365-1-5p mature miRNA
• Sequence: 16 - AGGGACUUUUGGGGGCAGAUGUG - 38
• Evidence: experimental ; Illumina [4]

Mature mmu-miR-365-3p

• Accession: MIMAT0000711
• Description: Mus musculus mmu-miR-365-3p mature miRNA
• Sequence: 56 - UAAUGCCCCUAAAAAUCCUUAU - 77
• Evidence: experimental ; cloned [2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


3. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009


4. PubMed ID: 15735639
   Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals
   "Xie X, Lu J, Kulbokas EJ, Golub TR, Mootha V, Lindblad-Toh K, Lander ES, Kellis M"
   "Nature (2005) 434:338-345