miRBase entry: mmu-mir-33

Stem-loop mmu-mir-33


Accession
MI0000707
Symbol
MGI: Mir33
Description
Mus musculus mmu-mir-33 precursor miRNA

Literature search
61 open access papers mention mmu-mir-33
(813 sentences)

Sequence

46129 reads, 412 reads per million, 105 experiments
cugugGUGCAUUGUAGUUGCAUUGCAuguucuggcaauaccugugCAAUGUUUCCACAGUGCAUCACgg
((((((((((((((.(..((((((((((....((.....))))))))))))..).))))))))))))))

Structure
              A UU          uucu  c 
cugugGUGCAUUGU G  GCAUUGCAug    gg a
|||||||||||||| |  ||||||||||    || a
ggCACUACGUGACA C  UGUAACgugu    cc u
              C UU          ----  a 


Annotation confidence High
Do you think this miRNA is real?
Comments
Mouse mir-33 is predicted [2] based on homology to a cloned miR from human (MIR:MI0000091) [1]. Its expression was later verified by cloning [3].

Genome context
chr15: 82198122-82198190 [+]

Database links

Mature mmu-miR-33-5p

Accession MIMAT0000667
Description Mus musculus mmu-miR-33-5p mature miRNA
Sequence 6 - GUGCAUUGUAGUUGCAUUGCA - 26
Evidence experimental
cloned [3], Illumina [4-5]
Database links
Predicted targets

Mature mmu-miR-33-3p

Accession MIMAT0004666
Description Mus musculus mmu-miR-33-3p mature miRNA
Sequence 46 - CAAUGUUUCCACAGUGCAUCAC - 67
Evidence experimental
cloned [3], Illumina [4-5]
Database links
Predicted targets

References

  1. PubMed ID: 11679670
    Identification of novel genes coding for small expressed RNAs
    "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
    "Science (2001) 294:853-858

  2. PubMed ID: 17604727
    A mammalian microRNA expression atlas based on small RNA library sequencing
    "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
    "Cell (2007) 129:1401-1414

  3. PubMed ID: 20215419
    MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
    "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
    "Mol Hum Reprod (2010) 16:463-471

  4. PubMed ID: 20413612
    Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
    "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
    "Genes Dev (2010) 24:992-1009

  5. PubMed ID: 15634332
    New human and mouse microRNA genes found by homology search
    "Weber MJ"
    "FEBS J (2005) 272:59-73