Stem-loop mmu-mir-300

Accession

MI0000400

Symbol

MGI: Mir300

Description

Mus musculus mmu-mir-300 precursor miRNA

Literature search

12 open access papers mention mmu-mir-300
(27 sentences)

Sequence

114279 reads, 583 reads per million, 84 experiments

gcuacUUGAAGAGAGGUUAUCCUUUGUguguuugcuuuacgcgaaaugaaUAUGCAAGGGCAAGCUCUCUUCgaggagc
(((.(((((((((((.((..((((((((((((((.(((....))).)))))))))))))).)).))))))))))).)))

Structure

   a           G  AU              c   a 
gcu cUUGAAGAGAG UU  CCUUUGUguguuug uuu c
||| ||||||||||| ||  |||||||||||||| |||  
cga gagCUUCUCUC AA  GGGAACGUAUaagu aag g
   g           G  -C              a   c 

Annotation confidence High

Genome context

chr12: 109724313-109724391 [+]

Clustered miRNAs

17 other miRNAs are < 10 kb from mmu-mir-300

Mature mmu-miR-300-5p

• Accession: MIMAT0004578
• Description: Mus musculus mmu-miR-300-5p mature miRNA
• Sequence: 6 - UUGAAGAGAGGUUAUCCUUUGU - 27
• Evidence: experimental ; cloned [2], Illumina [3-4]

Mature mmu-miR-300-3p

• Accession: MIMAT0000378
• Description: Mus musculus mmu-miR-300-3p mature miRNA
• Sequence: 51 - UAUGCAAGGGCAAGCUCUCUUC - 72
• Evidence: experimental ; cloned [1-2], Illumina [3-4]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358


3. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


4. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009