Accession
MI0000387
Description
Drosophila melanogaster
dme-bantam precursor miRNA bantam
Gene
family?
family?
RF00727;
bantam
Literature search
108 open access papers mention dme-bantam
(724 sentences)
(724 sentences)
Sequence
10432991
reads,
53750
reads per million, 49 experiments
auuugacuacgaaaCCGGUUUUCGAUUUGGUUUGACUguuuuucauacaagUGAGAUCAUUUUGAAAGCUGAUUuugucaa
........((((((.((((((((((..((((((.(((((.......)).))).))))))..)))))))))).))))))...
........((((((.((((((((((..((((((.(((((.......)).))).))))))..)))))))))).))))))...
Structure
auuugacu C UU G - uu
acgaaa CGGUUUUCGA UGGUUU ACU gu u
|||||| |||||||||| |||||| ||| || u
uguuUU GUCGAAAGUU ACUAGA Uga ca c
-----aac A UU G a ua
Annotation confidence
High
Do you think this miRNA is real?
Comments
bantam microRNA was predicted independently by two groups using computational approaches [1,2]. Northern blotting confirmed that the strand containing the predicted miR is predominantly expressed. Subsequent cloning studies have independently identified the same miRNA and confirmed the 5' end [3]. A length distribution of 20-23 nt was reported with a 23 nt sequence the most commonly expressed. bantam is reported to promote tissue growth [1]. bantam expression is temporally and spatially regulated in response to patterning cues. bantam microRNA simultaneously stimulates cell proliferation and prevents apoptosis and is predicted to target the pro-apoptotic gene hid [1].
Genome context
chr3L: 642208-642288 [+]
Database links
Mature dme-bantam-3p
| Accession | MIMAT0000365 |
| Description | Drosophila melanogaster dme-bantam-3p mature miRNA |
| Sequence | 52 - UGAGAUCAUUUUGAAAGCUGAUU - 74 |
| Evidence |
experimental
Northern [1], cloned [3], 454 [5-6], Illumina [6] |
| Database links |
|
| Predicted targets |
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Mature dme-bantam-5p
| Accession | MIMAT0020823 |
| Description | Drosophila melanogaster dme-bantam-5p mature miRNA |
| Sequence | 15 - CCGGUUUUCGAUUUGGUUUGACU - 37 |
| Evidence | not_experimental |
| Database links |
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References
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