Stem-loop mmu-mir-183

Accession

MI0000225

Symbol

MGI: Mir183

Description

Mus musculus mmu-mir-183 precursor miRNA mir-183

Gene
family

RF00663; mir-183

Literature search

106 open access papers mention mmu-mir-183
(972 sentences)

Sequence

419182 reads, 431 reads per million, 98 experiments

cugugUAUGGCACUGGUAGAAUUCACUgugaacagucucagucaGUGAAUUACCGAAGGGCCAUAAacag
((((.((((((.((((((..(((((((((((......)))..))))))))))))..)).)))))).))))

Structure

    g      A  --    GA        --   ac 
cugu UAUGGC CU  GGUA  AUUCACUg  uga  a
|||| |||||| ||  ||||  ||||||||  |||   
gaca AUACCG GA  CCAU  UAAGUGac  acu  g
    A      G  AG    --        ug   cu 

Annotation confidence High

Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

chr6: 30169668-30169737 [-]

Clustered miRNAs

2 other miRNAs are < 10 kb from mmu-mir-183

Mature mmu-miR-183-5p

• Accession: MIMAT0000212
• Description: Mus musculus mmu-miR-183-5p mature miRNA
• Sequence: 6 - UAUGGCACUGGUAGAAUUCACU - 27
• Evidence: experimental ; cloned [1-3], Illumina [4-5]

Mature mmu-miR-183-3p

• Accession: MIMAT0004539
• Description: Mus musculus mmu-miR-183-3p mature miRNA
• Sequence: 45 - GUGAAUUACCGAAGGGCCAUAA - 66
• Evidence: experimental ; cloned [3], Illumina [4-5]

References

1. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


2. PubMed ID: 12554859
   New microRNAs from mouse and human
   "Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T"
   "RNA (2003) 9:175-179


3. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358


4. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


5. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009