Stem-loop mmu-mir-130a

Accession

MI0000156

Symbol

MGI: Mir130a

Description

Mus musculus mmu-mir-130a precursor miRNA

Literature search

90 open access papers mention mmu-mir-130a
(645 sentences)

Sequence

190612 reads, 1739 reads per million, 106 experiments

gaGCUCUUUUCACAUUGUGCUACUgucuaacguguaccgagCAGUGCAAUGUUAAAAGGGCAUc
..((((((((.((((((((((.((...............)).)))))))))).))))))))...

Structure

-ga        C          A  gucuaa 
   GCUCUUUU ACAUUGUGCU CU      c
   |||||||| |||||||||| ||      g
   CGGGAAAA UGUAACGUGA ga      u
cUA        U          C  gccaug 

Annotation confidence High

Comments

This sequence was named miR-130 in reference [1], but is renamed here to avoid confusion with miR-130b (MIR:MI0000408).

Genome context

chr2: 84741115-84741178 [-]

Mature mmu-miR-130a-5p

• Accession: MIMAT0016983
• Description: Mus musculus mmu-miR-130a-5p mature miRNA
• Sequence: 3 - GCUCUUUUCACAUUGUGCUACU - 24
• Evidence: experimental ; Illumina [8]

Mature mmu-miR-130a-3p

• Accession: MIMAT0000141
• Description: Mus musculus mmu-miR-130a-3p mature miRNA
• Sequence: 42 - CAGUGCAAUGUUAAAAGGGCAU - 63
• Evidence: experimental ; cloned [1-2,4-6], Northern [2], Illumina [7]

References

1. PubMed ID: 12554860
   Numerous microRNPs in neuronal cells containing novel microRNAs
   "Dostie J, Mourelatos Z, Yang M, Sharma A, Dreyfuss G"
   "RNA (2003) 9:180-186


2. PubMed ID: 17604727
   A mammalian microRNA expression atlas based on small RNA library sequencing
   "Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M"
   "Cell (2007) 129:1401-1414


3. PubMed ID: 12919684
   Embryonic stem cell-specific MicroRNAs
   "Houbaviy HB, Murray MF, Sharp PA"
   "Dev Cell (2003) 5:351-358


4. PubMed ID: 12007417
   Identification of tissue-specific microRNAs from mouse
   "Lagos-Quintana M, Rauhut R, Yalcin A, Meyer J, Lendeckel W, Tuschl T"
   "Curr Biol (2002) 12:735-739


5. PubMed ID: 15538371
   A pancreatic islet-specific microRNA regulates insulin secretion
   "Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M"
   "Nature (2004) 432:226-230


6. PubMed ID: 16766679
   Identification and characterization of two novel classes of small RNAs in the mouse germline: retrotransposon-derived siRNAs in oocytes and germline small RNAs in testes
   "Watanabe T, Takeda A, Tsukiyama T, Mise K, Okuno T, Sasaki H, Minami N, Imai H"
   "Genes Dev (2006) 20:1732-1743


7. PubMed ID: 20215419
   MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing
   "Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A"
   "Mol Hum Reprod (2010) 16:463-471


8. PubMed ID: 20413612
   Mammalian microRNAs: experimental evaluation of novel and previously annotated genes
   "Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP"
   "Genes Dev (2010) 24:992-1009