Stem-loop dme-mir-5

Accession

MI0000123

Description

Drosophila melanogaster dme-mir-5 precursor miRNA mir-5

Gene
family

RF00854; mir-5

Literature search

10 open access papers mention dme-mir-5
(35 sentences)

Sequence

68714 reads, 2797 reads per million, 49 experiments

gcuaAAAGGAACGAUCGUUGUGAUAUGaguuguuuccuaacaUAUCACAGUGAUUUUCCUUUAUAacgc
....(((((((.(((((((((((((((.............)))))))))))))))))))))).......

Structure

---gcua       C               aguug 
       AAAGGAA GAUCGUUGUGAUAUG     u
       ||||||| |||||||||||||||     u
       UUUCCUU UUAGUGACACUAUac     u
cgcaAUA       -               aaucc 

Annotation confidence Medium

Genome context

chr2R: 19661158-19661226 [-]

Clustered miRNAs

7 other miRNAs are < 10 kb from dme-mir-5

Mature dme-miR-5-5p

• Accession: MIMAT0000110
• Description: Drosophila melanogaster dme-miR-5-5p mature miRNA
• Sequence: 5 - AAAGGAACGAUCGUUGUGAUAUG - 27
• Evidence: experimental ; cloned [1,3], Northern [1-2], 454 [4-5], Illumina [5]

Mature dme-miR-5-3p

• Accession: MIMAT0020786
• Description: Drosophila melanogaster dme-miR-5-3p mature miRNA
• Sequence: 43 - UAUCACAGUGAUUUUCCUUUAUA - 65
• Evidence: not_experimental

References

1. PubMed ID: 11679670
   Identification of novel genes coding for small expressed RNAs
   "Lagos-Quintana M, Rauhut R, Lendeckel W, Tuschl T"
   "Science (2001) 294:853-858


2. PubMed ID: 12812784
   Temporal regulation of microRNA expression in Drosophila melanogaster mediated by hormonal signals and broad-Complex gene activity
   "Sempere LF, Sokol NS, Dubrovsky EB, Berger EM, Ambros V"
   "Dev Biol (2003) 259:9-18


3. PubMed ID: 12919683
   The small RNA profile during Drosophila melanogaster development
   "Aravin AA, Lagos-Quintana M, Yalcin A, Zavolan M, Marks D, Snyder B, Gaasterland T, Meyer J, Tuschl T"
   "Dev Cell (2003) 5:337-350


4. PubMed ID: 17989254
   Evolution, biogenesis, expression, and target predictions of a substantially expanded set of Drosophila microRNAs
   "Ruby JG, Stark A, Johnston WK, Kellis M, Bartel DP, Lai EC"
   "Genome Res (2007) 17:1850-1864


5. PubMed ID: 17989255
   Systematic discovery and characterization of fly microRNAs using 12 Drosophila genomes
   "Stark A, Kheradpour P, Parts L, Brennecke J, Hodges E, Hannon GJ, Kellis M"
   "Genome Res (2007) 17:1865-1879