Search results

lin-4 family in Rfam (RF00052)

Summary
This family represents the microRNA (miRNA) lin-4 (MIPF:MIPF0000303). lin-4 was identified from a study of developmental timing in C. elegans [1], and was later shown to be part of a much larger class of non-coding RNAs termed miRNAs [2]. miRNAs are transcribed as ~70nt precursors (modelled here) and subsequently processed by the Dicer enzyme to give a ~22nt product. The extents of the hairpin precursors are not generally known and are estimated based on hairpin prediction. The products are thought to have regulatory roles through complementarity to mRNA. The involvement of Dicer in miRNA processing suggests a relationship with the phenomenon of RNA interference.
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5'

There are 7 hairpins in the lin-4 family

Name Accession RPM Chromosome Start End Strand Confidence
cel-lin-4 MI0000002 2214 chrII 5902254 5902347 + High
cbr-lin-4 MI0000492 - chrII 9816746 9816839 - -
crm-lin-4 MI0011095 - Crem_Contig17 1151377 1151480 + -
bma-lin-4 MI0013320 - Bmal_v3_scaffold17 230335 230424 - -
asu-lin-4 MI0018524 - None None -
cbn-lin-4-1 MI0024907 - Cbre_Contig36 499331 499391 + -
cbn-lin-4-2 MI0024908 - Cbre_Contig639 19743 19803 + -



Comments or questions? Email mirbase@manchester.ac.uk