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2 publications mentioning chi-mir-409

Open access articles that are associated with the species Capra hircus and mention the gene name mir-409. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 45
Most notable was the fact that the expressions of miR-409-3p (down-regulated in FD) and miR-451-5p (up-regulated in FD) appeared to be sensitive to caloric restriction. [score:9]
Conversely, miR-409-3p was down-regulated in the blood of mice receiving about 60% of their normal diet, whereas the expression of miR-451-5p was increased [42]. [score:6]
Looking at the abundance of the 30 nutriregulated miRNA, two known miRNA (miR-126-3p and miR-6119-5p) were very highly expressed with normalized read counts greater than 10,000, while seven (let-7c-5p, miR-99a-5p, miR-125b-3p, miR-140-3p, miR-409-3p, miR-451-5p and miR-660-5p) were highly expressed and represented by normalized read counts of between 1,000 and 10,000 (Table 2). [score:6]
Seven miRNA were chosen for RT-qPCR validation among known miRNA which expression was affected by the food deprivation and based on their level of expression; miR-99a-5p (TaqMan [®] ID 006254_mat, Applied Biosystems), miR-126-3p (TaqMan [®] ID 008451_mat), miR-140-3p (TaqMan [®] ID 471823_mat), miR-222-3p (TaqMan [®] ID 000525), miR-223-3p (TaqMan [®] ID 002295), miR-204-5p (TaqMan [®] ID 000508), miR-409-3p (TaqMan [®] ID 002332). [score:5]
As well as having many putative targets involved in lipid metabolism (Fig 3, S4 Table), miR-494-3p and miR-409-3p are also positioned in QTL regions associated with milk fatty acids, thus rendering these two miRNA good candidates to study their involvement in the regulation of milk lipid synthesis. [score:4]
In particular, miR-409-3p and miR-494-3p may target numerous genes involved in lipid metabolism and its regulation. [score:4]
The expressions of miR-223-3p and miR-409-3p were increased, whereas that of miR-451-5p was decreased in skeletal muscle of monkeys receiving a restricted diet [26]. [score:3]
Interestingly, miR-222-3p, miR-409-3p, miR-541-5p, miR-6119-5p, miR-660-5p, chr23_30758-5p and chr3_4386-5p potentially target several genes coding for casein kinases 1 and 2 alpha and gamma (S4 Table). [score:3]
Among the nutriregulated miRNA, five (miR-126-3p, miR-140-3p, miR-223-3p, miR-409-3p, miR-451-5p) have previously been described as being affected by caloric restriction in others species and tissues. [score:2]
Indeed, miR-409-3p and miR-494-3p belonged to the mir-154 family and miR-188-5p and miR-660-5p to the mir-188 family (Table 2). [score:1]
Indeed, miR-494-3p, miR-409-3p and miR-541-5p are members of the greatest and conserved miRNA cluster located on goat chromosome 21. [score:1]
Furthermore, mir-409, mir-494 and mir-541 belonging to a large and conserved cluster in mammals have also been located in QTL associated with milk yield and milk fat percentage and content on bovine chromosome 21. [score:1]
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2
[+] score: 8
However, 17 down-regulated miRNAs were common between three prenatal stages and the neonatal stage, including chi-miR-409-3p, chi-miR-376b-3p, and chi-miR-135a. [score:4]
In particular, the expressions of 26 DE known miRNAs in Profile 12 were stable at prenatal stages and then went down on day three after birth, such as chi-miR-127-5p, chi-miR-409-3p, and chi-miR-432-5p. [score:3]
These included chi-miR-127-5p, chi-miR-409-3p, and chi-miR-432-5p. [score:1]
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