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miRBase |
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![]() 5 publications mentioning rno-mir-149Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-149. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary. |
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Other miRNAs from this paper: rno-let-7d, rno-mir-342, rno-let-7a-1, rno-let-7a-2, rno-let-7b, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7f-1, rno-let-7f-2, rno-let-7i, rno-mir-21, rno-mir-26a, rno-mir-34a, rno-mir-146a, rno-mir-210, rno-mir-320, rno-mir-451, rno-mir-224, rno-mir-423, rno-mir-455, rno-mir-146b, rno-mir-1949, rno-let-7g, rno-mir-193b, rno-mir-3084a-1, rno-mir-3084a-2, rno-mir-3084b, rno-mir-3084a-3, rno-mir-3084a-4
Yang D. Du G. Xu A. Xi X. Li D. Expression of miR-149–3p inhibits proliferation, migration, and invasion of bladder cancer by targeting S100A4Am.
[score:7]
Although not directly linked to kidney injury, upregulation of miR-149-3p may decrease clonogenicity and induce apoptosis by targeting polo-like kinase 1 (PLK1) [45].
[score:7]
Additionally, miR-149-3p inhibits the proliferation, migration, and invasion of bladder cancer cells by targeting the S100A4 protein, which is involved with cellular differentiation, motility, and regulating transcription [46].
[score:6]
miR-21-5p, miR-34a-5p, miR-146b-5p, miR-149-3p, miR-224-5p, miR-451-5p, miR-1949, miR-3084a-3p, and miR-3084c-3p were more abundantly expressed and demonstrated a two-fold or greater increased expression in the Cd-treatment group.
[score:5]
miR-21-5p, miR-34a-5p, miR-146b-5p, miR-149-3p, miR-224-5p, miR-451-5p, miR-1949, miR-3084a-3p, and miR-3084c-3p demonstrated more abundant expression and a two-fold or greater significant increase in expression with Cd treatment.
[score:5]
Shin C. H. Lee H. Kim H. R. Choi K. H. Joung J. G. Kim H. H. Regulation of PLK1 through competition between hnRNPK, miR-149–3p and miR-193b-5pCell Death Differ.
[score:2]
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Other miRNAs from this paper: rno-let-7d, rno-mir-140, rno-mir-340-1, rno-mir-351-1, rno-let-7a-1, rno-let-7a-2, rno-let-7f-1, rno-mir-18a, rno-mir-24-1, rno-mir-26b, rno-mir-98, rno-mir-126a, rno-mir-132, rno-mir-139, rno-mir-184, rno-mir-200a, rno-mir-214, rno-mir-224, rno-mir-411, rno-mir-532, rno-mir-92b, rno-mir-490, rno-mir-547, rno-mir-3559, rno-mir-126b, rno-mir-3596b, rno-mir-340-2, rno-mir-351-2, rno-mir-676
HM also upregulated miR-149-5p expression in colon tissues, whereas miR-149-5p functioned on the transcription factor FOXM1 to inhibit the migration of tumor cells in the colon [51].
[score:8]
The upregulated miRNAs in the colon tissues of UC rats changed by HM were miR-149-5p, miR-351-5p, let-7d-5p, miR-98-5p, let-7a-5p, miR-3559-5p, let-7f-1-3p, miR-3596b, miR-224-5p, miR-411-3p, miR-184, miR-26b-3p, and miR-92b-3p.
[score:4]
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Other miRNAs from this paper: hsa-mir-21, mmu-mir-141, mmu-mir-142a, mmu-mir-149, mmu-mir-155, mmu-mir-185, mmu-mir-200b, mmu-mir-204, hsa-mir-34a, hsa-mir-204, hsa-mir-210, hsa-mir-224, hsa-mir-200b, hsa-mir-141, hsa-mir-142, hsa-mir-149, hsa-mir-185, mmu-mir-200a, mmu-mir-21a, mmu-mir-34a, hsa-mir-200c, hsa-mir-155, mmu-mir-200c, mmu-mir-210, mmu-mir-224, hsa-mir-200a, rno-mir-21, rno-mir-34a, rno-mir-141, rno-mir-142, rno-mir-185, rno-mir-200c, rno-mir-200a, rno-mir-200b, rno-mir-204, rno-mir-210, rno-mir-224, mmu-mir-21b, mmu-mir-21c, rno-mir-155, mmu-mir-142b
For instance, loss of miR-149, miR-200c and mir-141 causes gain of function of oncogenes (KCNMA1, LOX), VEGFA and SEMA6A respectively and increased levels of miR-142-3p, miR-185, mir-34a, miR-224, miR-21 cause loss of function of tumor suppressors LRRC2, PTPN13, SFRP1, ERBB4, and (SLC12A1, TCF21) respectively.
[score:3]
As the p-values in Figure 4 indicate, we validate a strong anti-correlation signature between mRNA levels of (KCNMA1, LOX), VEGF, SEMA6A, (LRRC2, PTPN13), SFRP1, ERBB4, SLC12A1 and TCF21, and their identified regulators: miR-149, miR-200c, mir-141, miR-142-3p, miR-185, mir-34a, miR-224 and miR-21 respectively.
[score:2]
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Other miRNAs from this paper: rno-mir-21, rno-mir-27b, rno-mir-27a, rno-mir-29b-2, rno-mir-29a, rno-mir-29b-1, rno-mir-29c-1, rno-mir-30c-1, rno-mir-30c-2, rno-mir-31a, rno-mir-133a, rno-mir-145, rno-mir-199a, rno-mir-208a, rno-mir-211, rno-mir-214, rno-mir-221, rno-mir-222, rno-mir-1, rno-mir-133b, rno-mir-31b, rno-mir-133c, rno-mir-15a, rno-mir-29c-2, rno-mir-29b-3, rno-mir-486
Three miRNAs of this initial cardiovascular reference list, however, are not 100% conserved between human and rat (miR-1, miR-211 and miR-424) and six miRNAs have not yet been registered for rats (miR-7g, miR-149, miR-15a, miR-199b, miR-372 and miR-486).
[score:1]
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Other miRNAs from this paper: rno-mir-330, rno-mir-20a, rno-mir-10a, rno-mir-10b, rno-mir-25, rno-mir-29b-2, rno-mir-29b-1, rno-mir-93, rno-mir-103-2, rno-mir-103-1, rno-mir-128-1, rno-mir-128-2, rno-mir-133a, rno-mir-142, rno-mir-146a, rno-mir-206, rno-mir-1, rno-mir-133b, rno-mir-499, rno-mir-410, rno-mir-455, rno-mir-208b, rno-mir-3068, rno-mir-29b-3, rno-mir-486
From 30 selected miRNAs, 6 miRNAs were found altered within muscle tissue after exercise, while just 2 circulating miRNAs (miR-133a, miR-149) were found increased 4 h after exercise (Orton et al., 2005).
[score:1]
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