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5 publications mentioning rno-mir-149

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-149. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 32
Yang D. Du G. Xu A. Xi X. Li D. Expression of miR-149–3p inhibits proliferation, migration, and invasion of bladder cancer by targeting S100A4Am. [score:7]
Although not directly linked to kidney injury, upregulation of miR-149-3p may decrease clonogenicity and induce apoptosis by targeting polo-like kinase 1 (PLK1) [45]. [score:7]
Additionally, miR-149-3p inhibits the proliferation, migration, and invasion of bladder cancer cells by targeting the S100A4 protein, which is involved with cellular differentiation, motility, and regulating transcription [46]. [score:6]
miR-21-5p, miR-34a-5p, miR-146b-5p, miR-149-3p, miR-224-5p, miR-451-5p, miR-1949, miR-3084a-3p, and miR-3084c-3p were more abundantly expressed and demonstrated a two-fold or greater increased expression in the Cd-treatment group. [score:5]
miR-21-5p, miR-34a-5p, miR-146b-5p, miR-149-3p, miR-224-5p, miR-451-5p, miR-1949, miR-3084a-3p, and miR-3084c-3p demonstrated more abundant expression and a two-fold or greater significant increase in expression with Cd treatment. [score:5]
Shin C. H. Lee H. Kim H. R. Choi K. H. Joung J. G. Kim H. H. Regulation of PLK1 through competition between hnRNPK, miR-149–3p and miR-193b-5pCell Death Differ. [score:2]
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[+] score: 12
HM also upregulated miR-149-5p expression in colon tissues, whereas miR-149-5p functioned on the transcription factor FOXM1 to inhibit the migration of tumor cells in the colon [51]. [score:8]
The upregulated miRNAs in the colon tissues of UC rats changed by HM were miR-149-5p, miR-351-5p, let-7d-5p, miR-98-5p, let-7a-5p, miR-3559-5p, let-7f-1-3p, miR-3596b, miR-224-5p, miR-411-3p, miR-184, miR-26b-3p, and miR-92b-3p. [score:4]
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[+] score: 5
For instance, loss of miR-149, miR-200c and mir-141 causes gain of function of oncogenes (KCNMA1, LOX), VEGFA and SEMA6A respectively and increased levels of miR-142-3p, miR-185, mir-34a, miR-224, miR-21 cause loss of function of tumor suppressors LRRC2, PTPN13, SFRP1, ERBB4, and (SLC12A1, TCF21) respectively. [score:3]
As the p-values in Figure 4 indicate, we validate a strong anti-correlation signature between mRNA levels of (KCNMA1, LOX), VEGF, SEMA6A, (LRRC2, PTPN13), SFRP1, ERBB4, SLC12A1 and TCF21, and their identified regulators: miR-149, miR-200c, mir-141, miR-142-3p, miR-185, mir-34a, miR-224 and miR-21 respectively. [score:2]
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[+] score: 1
Three miRNAs of this initial cardiovascular reference list, however, are not 100% conserved between human and rat (miR-1, miR-211 and miR-424) and six miRNAs have not yet been registered for rats (miR-7g, miR-149, miR-15a, miR-199b, miR-372 and miR-486). [score:1]
[1 to 20 of 1 sentences]
[+] score: 1
From 30 selected miRNAs, 6 miRNAs were found altered within muscle tissue after exercise, while just 2 circulating miRNAs (miR-133a, miR-149) were found increased 4 h after exercise (Orton et al., 2005). [score:1]
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