sort by

26 publications mentioning rno-mir-148a

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-148a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 22
In the present study, the expression of miR-148a and miR-148b both increased in ischemic rat brain SVZ, we speculate that reduction of blood flow and oxygen input may induce miR-148a/b expression. [score:5]
MiR-148/152 family members are down-regulated in various cancer cell lines, which indicates the members in this family potential effect in regulating cell cycle, proliferation, and apoptosis (Yu et al., 2009; Song et al., 2011, 2012). [score:4]
The expression of miR-148/152 family could be altered by exposure to certain physical and chemical factors (Chen et al., 2013). [score:3]
Quantitate RT-PCR analysis indicated the expression levels of both miR-148a and miR-148b in ischemic SVZ were obviously increased compared with sham group (Figure 1B). [score:2]
Several studies showed miR-148/152 family members regulate not only proliferation but also differentiation process in stem cells (Yu et al., 2012; Fujiwara and Ozaki, 2016). [score:2]
To explore the potential involvement of miR-148 in ischemic SVZ, sub-ventricular zone was isolated from sham-operation (Sham) and MCAo applied rat brains (Figure 1A). [score:1]
The microRNA-148/152 family: multi-faceted players. [score:1]
MiRNA-148b belongs to miRNA-148/152 (miR-148/152) family, which has been elucidated to involved in various biological processes (Chen et al., 2013). [score:1]
SVZ (marked with black rectangle) in ischemic hemisphere and the corresponding area from sham group rats were isolated respectively for qRT-PCR test; (B) miR-148a/b expression levels were measured in sham and MCAo rat SVZ area. [score:1]
Due to the low enrichment of miR-148a in SVZ, we focused our study on miR-148b. [score:1]
However, the enrichment of miR-148a in sham and ischemic brains were significantly lower than miR-148b, and the following study was focused on miR-148b. [score:1]
[1 to 20 of 11 sentences]
2
[+] score: 13
B13 cells that were transduced with Ad-PNM showed upregulation of 6 miRNAs (miR-134-5p, miR-455-3p, miR-384-5p, miR-137-3p, miR-135a-5p and miR-22-5p) and downregulation of 2 miRNAs (miR-335-3p and miR-148a-5p). [score:7]
Among the overexpressed miRNAs, miR-148a, miR-335, miR-132 and miR-204 were identified, all of which have been reported to be overexpressed in β cells in comparison with α cells [44], suggesting that adenoviral transduction aids in cellular reprogramming toward a β cell lineage. [score:5]
9 miRNAs were present in two categories; 5 of them were common between Tables 1 and 2 (miR-181a-5p, miR-204-5p and miR-2137, miR-421-3p and miR-483-3p), two miRNAs were present in both Tables 2 and 3 (miR-148a-5p and piR-335-3p) and the remaining two miRNAs were classified both in Tables 1 and 3 (miR-137-3p and miR-455-3p). [score:1]
[1 to 20 of 3 sentences]
3
[+] score: 11
MiR-148-3p, mir-17-5p, miR-181a-5p, miR-19b-3p and miR-24-3p were predicted to control the expression of the following target genes: Interleukin 6 signal transducer IL6ST (gp130). [score:5]
In contrast, there was no change in the expression of mir148-3p or mir19b-3p (Fig 5). [score:3]
Amongst the 5 miRNAs (miR148-3p, miR17-5p, miR181a-5p, miR19b-3p and miR24-3p) targeting multiple genes from our 70 genes list, mir17-5p, which is increased with stress was confirmed by qRT-PCR. [score:3]
[1 to 20 of 3 sentences]
4
[+] score: 9
Inhibition of FGF signaling through SU5402 -treated primitive streak regions of chick embryos identified up-regulation of let-7b, miR-9, miR-19b, miR-107, miR-130b, miR-148a, miR-203, and miR-218 and down-regulation of miR-29a and miR-489 (Bobbs et al. 2012). [score:9]
[1 to 20 of 1 sentences]
5
[+] score: 9
miR-451 had only one predicted target in common between the databases, whereas miR-148a, miR-21 and miR-205 had 200 to 300 putative target genes. [score:5]
Based on qRT-PCR analysis, the expression of miR-451, miR-148a, miR-21, miR-205 and miR-193a were not different between the sexes and therefore contrasted the microarray results. [score:3]
However, miR-451, miR-148a and miR-193 have recently been detected in liver by a high-throughput sequencing approach (Sarah Leigh-Brown, personal communication). [score:1]
[1 to 20 of 3 sentences]
6
[+] score: 8
miRNA Target Genes Pathways miR-128 ABCB9, BTG1, DSCR1, RASD1 ABC transporters General miR-136 GRN, PPP1R9B miR-147 HOXA1, PTGFRN miR-148 EGR3, SCN3A miR-181b IGF1R, NKX6-1 Adherens junction, Maturity onset diabetes of the, Focal adhesion, **Long term depression miR-196a ABCB9, CPB2, IRS1, MAPK10 ABC transporters General, Complement and coagulation cas, Adipocytokine signaling pathwa, Insulin signaling pathway, Type II diabetes mellitus, Fc epsilon RI signaling pathwa, Focal adhesion, **GnRH signaling pathway, **MAPK signaling pathway, Toll like receptor signaling p, Wnt signaling pathway miR-203 SARA1 miR-20 BTG1, SARA1, YWHAB Cell cycle miR-21 TPM1 mir-216 GNAZ **Long term depression miR-217 RHOA Adherens junction, Axon guidance, Focal adhesion, Leukocyte transendothelial mig, Regulation of actin cytoskelet, TGF beta signaling pathway, T cell receptor signaling path, Tight junction, Wnt signaling pathway miR-31 ATP2B2, DNM1L, EGR3, PPP1R9B, YWHAB **Calcium signaling pathway, Cell cycle miR-7 SLC23A2 miR-7b HRH3, NCDN, SLC23A2 **Neuroactive ligand receptor in b: miRNAs and their targets (from TargetScan and miRanda). [score:8]
[1 to 20 of 1 sentences]
7
[+] score: 8
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-17, hsa-mir-18a, hsa-mir-20a, hsa-mir-21, hsa-mir-22, hsa-mir-26a-1, hsa-mir-99a, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-106a, hsa-mir-107, mmu-let-7g, mmu-let-7i, mmu-mir-99a, mmu-mir-101a, mmu-mir-125a, mmu-mir-125b-2, mmu-mir-126a, mmu-mir-127, mmu-mir-145a, mmu-mir-146a, mmu-mir-129-1, mmu-mir-206, hsa-mir-129-1, hsa-mir-148a, mmu-mir-122, mmu-mir-143, hsa-mir-139, hsa-mir-221, hsa-mir-222, hsa-mir-223, mmu-let-7d, mmu-mir-106a, hsa-let-7g, hsa-let-7i, hsa-mir-122, hsa-mir-125b-1, hsa-mir-143, hsa-mir-145, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-127, hsa-mir-129-2, hsa-mir-146a, hsa-mir-206, mmu-mir-148a, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-18a, mmu-mir-20a, mmu-mir-21a, mmu-mir-22, mmu-mir-26a-1, mmu-mir-129-2, mmu-mir-103-1, mmu-mir-103-2, rno-let-7d, rno-mir-335, rno-mir-129-2, rno-mir-20a, mmu-mir-107, mmu-mir-17, mmu-mir-139, mmu-mir-223, mmu-mir-26a-2, mmu-mir-221, mmu-mir-222, mmu-mir-125b-1, hsa-mir-26a-2, hsa-mir-335, mmu-mir-335, rno-let-7a-1, rno-let-7a-2, rno-let-7b, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7f-1, rno-let-7f-2, rno-let-7i, rno-mir-17-1, rno-mir-18a, rno-mir-21, rno-mir-22, rno-mir-26a, rno-mir-99a, rno-mir-101a, rno-mir-103-2, rno-mir-103-1, rno-mir-107, rno-mir-122, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-126a, rno-mir-127, rno-mir-129-1, rno-mir-139, rno-mir-143, rno-mir-145, rno-mir-146a, rno-mir-206, rno-mir-221, rno-mir-222, rno-mir-223, hsa-mir-196b, mmu-mir-196b, rno-mir-196b-1, hsa-mir-20b, hsa-mir-451a, mmu-mir-451a, rno-mir-451, hsa-mir-486-1, hsa-mir-499a, mmu-mir-486a, mmu-mir-20b, rno-mir-20b, rno-mir-499, mmu-mir-499, mmu-mir-708, hsa-mir-708, rno-mir-17-2, rno-mir-708, hsa-mir-103b-1, hsa-mir-103b-2, mmu-mir-486b, rno-mir-126b, hsa-mir-451b, hsa-mir-499b, mmu-mir-145b, mmu-mir-21b, mmu-let-7j, mmu-mir-130c, mmu-mir-21c, mmu-mir-451b, mmu-let-7k, hsa-mir-486-2, mmu-mir-129b, mmu-mir-126b, rno-let-7g, rno-mir-196b-2, rno-mir-486
By 18 wks of E [2] treatment, the mammary glands were characterized by lobular involution and hyperplasia, and only 1 miRNA was down-regulated (miR-139) and 5 miRNAs were up-regulated (miR-20b, miR-21, miR-103, mir-107, miR-129-3p, and miR-148a). [score:5]
E [2] decreased miR-146a, miR 125a, miR-125b, let-7e, miR-126, miR-145, and miR-143 and increased miR-223, miR-451, miR-486, miR-148a, miR-18a, and miR-708 expression in mouse splenic lymphocytes [199]. [score:3]
[1 to 20 of 2 sentences]
8
[+] score: 7
Those miRNAs, we call them the epi-miRNAs, includes, for example, miR-148a, miR152, miR222 that targets mRNA of DNMTs and leads to re -expression of hyper-methylated tumor suppressors [32]. [score:7]
[1 to 20 of 1 sentences]
9
[+] score: 6
Additionally, another evidence collected from the current inverstigation demonstrate that the microRNA -mediated regulation is not limited to the 3’UTR, the functionality of target sites in the CDS also confirmed by previous studies [57– 59], such as miR-24 [58], miR-296, miR-470, miR-134 [60], miR-126 [43], miR-181a [59], miR-148 [57] and miR-519 [61] that target sequences within the mRNA coding region have been reported to repress the biosynthesis of the encoded proteins in similar way. [score:6]
[1 to 20 of 1 sentences]
10
[+] score: 5
MiR-148a and miR-148b, which are found in UC blood MSC-derived exosomes, reportedly regulate the proliferation of UC blood MSCs by upregulating NF-κB or hedgehog signalling [38]. [score:5]
[1 to 20 of 1 sentences]
11
[+] score: 4
As development proceeds, the observed increases of miR-29c, miR-375, miR-148, and miR-200c may drive the observed decreased expression of Klf4 mRNA. [score:4]
[1 to 20 of 1 sentences]
12
[+] score: 3
Four of the 18 novel miRNAs were among the 50 most highly expressed miRNAs in the rat DRG (mmu-miR-486-5p, rnoH-miR-148a-3p, rnoH-let-7 g and rnoH-miR-676-3p, set in italics in Additional file 1: Table S1). [score:3]
[1 to 20 of 1 sentences]
13
[+] score: 3
In relation to the potential role of Sry in regulating brain sexual differentiation, circSry consists of 16 potential binding sites for miR-148 (Hansen et al., 2013), which is abundant in neuronal and other cell types (Obernosterer et al., 2006; Morton et al., 2008; Eskildsen et al., 2011). [score:2]
One example as discussed previously is that circSry might act as a “miRNA sponge” by binding to ncRNAs and thereby rendering them inactive, as might occur for miR-148 in brain neuronal cells (Obernosterer et al., 2006; Morton et al., 2008; Eskildsen et al., 2011; Hansen et al., 2013). [score:1]
[1 to 20 of 2 sentences]
14
[+] score: 3
Other miRNAs from this paper: hsa-let-7a-2, hsa-let-7c, hsa-let-7e, hsa-mir-15a, hsa-mir-16-1, hsa-mir-21, hsa-mir-22, hsa-mir-23a, hsa-mir-24-2, hsa-mir-100, hsa-mir-29b-2, mmu-let-7i, mmu-mir-99b, mmu-mir-125a, mmu-mir-130a, mmu-mir-142a, mmu-mir-144, mmu-mir-155, mmu-mir-183, hsa-mir-196a-1, mmu-mir-199a-1, hsa-mir-199a-1, mmu-mir-200b, hsa-mir-148a, mmu-mir-143, hsa-mir-181c, hsa-mir-183, hsa-mir-199a-2, hsa-mir-199b, hsa-mir-181a-1, hsa-mir-200b, mmu-mir-298, mmu-mir-34b, hsa-let-7i, hsa-mir-124-1, hsa-mir-124-2, hsa-mir-130a, hsa-mir-142, hsa-mir-143, hsa-mir-144, hsa-mir-125a, mmu-mir-148a, mmu-mir-196a-1, mmu-let-7a-2, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-mir-15a, mmu-mir-16-1, mmu-mir-21a, mmu-mir-22, mmu-mir-23a, mmu-mir-24-2, rno-mir-148b, mmu-mir-148b, hsa-mir-200c, hsa-mir-155, mmu-mir-100, mmu-mir-200c, mmu-mir-181a-1, mmu-mir-29b-2, mmu-mir-199a-2, mmu-mir-199b, mmu-mir-124-1, mmu-mir-124-2, mmu-mir-181c, hsa-mir-34b, hsa-mir-99b, hsa-mir-374a, hsa-mir-148b, rno-let-7a-2, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7i, rno-mir-21, rno-mir-22, rno-mir-23a, rno-mir-24-2, rno-mir-29b-2, rno-mir-34b, rno-mir-99b, rno-mir-100, rno-mir-124-1, rno-mir-124-2, rno-mir-125a, rno-mir-130a, rno-mir-142, rno-mir-143, rno-mir-144, rno-mir-181c, rno-mir-183, rno-mir-199a, rno-mir-200c, rno-mir-200b, rno-mir-181a-1, rno-mir-298, hsa-mir-193b, hsa-mir-497, hsa-mir-568, hsa-mir-572, hsa-mir-596, hsa-mir-612, rno-mir-664-1, rno-mir-664-2, rno-mir-497, mmu-mir-374b, mmu-mir-497a, mmu-mir-193b, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-568, hsa-mir-298, hsa-mir-374b, rno-mir-466b-1, rno-mir-466b-2, hsa-mir-664a, mmu-mir-664, rno-mir-568, hsa-mir-664b, mmu-mir-21b, mmu-mir-21c, rno-mir-155, mmu-mir-142b, mmu-mir-497b, rno-mir-15a, rno-mir-193b
Among them are two polycistronic transcripts (miR-15a~16-1 and miR-193b~365-1), and two expressing single miRNAs (miR-148a and miR-155). [score:3]
[1 to 20 of 1 sentences]
15
[+] score: 3
Moreover, miR-148a-3p, -370-3p, -379-5p, -99a-5p and let-7f-5p showed a significant expression increase in KOC-consuming rats, although no significant changes had been found by mass sequencing. [score:3]
[1 to 20 of 1 sentences]
16
[+] score: 3
Among miRNAs preferentially expressed in the heart (Figure 4) mir-148a, mir-101, and mir-138 are particularly important. [score:3]
[1 to 20 of 1 sentences]
17
[+] score: 3
Some of the diabetes -associated miRNAs were below the detection limit in our study, such as miR-9, miR-96 and miR-148, indicating that back-translation from humans to ZDF rats may be difficult for these markers. [score:3]
[1 to 20 of 1 sentences]
18
[+] score: 2
On the other hand, 7 miRNAs (mir-138-2, miR-148a-5p, mir-299a, miR-299a-5p, miR-493-3p, miR-540-5p, and miR-667-3p) have reported significant changes in miRNAs that only show directional changes opposite to what we observed (31, 32, 37, 38). [score:2]
[1 to 20 of 1 sentences]
19
[+] score: 2
The DNMT family can be regulated by several miRs such as miR-29b, miR-148a and miR-152 [23]– [25], [27]. [score:2]
[1 to 20 of 1 sentences]
20
[+] score: 2
sham rat) Peers' studies hsa-miR-34a-3p 2.63 upUp, Jess Morhayim[15] hsa-miR-433-3p 1.24 up This study hsa-miR-106b 2.24 up This study hsa-miR-23a 0.48 downDown, Sylvia Weilner[27] hsa-miR-328-3p 0.38 down Down, Sylvia Weilner hsa-miR-29b-3p 2.1 up Up, Jess Morhayim hsa-miR-146a-5p 2.68 up Up, Jess Morhayim hsa-miR-148a-3p 1.85 upUp, Cheng[28] We noted that DKK1 played important role in the development of osteoporosis. [score:2]
[1 to 20 of 1 sentences]
21
[+] score: 2
Other miRNAs from this paper: rno-mir-148b, rno-mir-21, rno-mir-25, rno-mir-26a, rno-mir-133a
In a set of wheezing + LRI patients (n = 20) and age- and gender-matched LRI control children (n = 20), miR-21, miR-25, miR-26a, miR-133a and miR-148 showed potential statistical differences between the patient and control groups (p < 0.10) (Fig.   1a). [score:1]
b RT-qPCR results of miR-21, miR-25, miR-26a, miR-133a and miR-148 in plasma from 35 indifferent control, 35 LRI control and 70 wheezing + LRI children. [score:1]
[1 to 20 of 2 sentences]
22
[+] score: 2
Muiños-Gimeno M. Espinosa-Parrilla Y. Guidi M. Kagerbauer B. Sipilä T. Maron E. Pettai K. Kananen L. Navinés R. Martín-Santos R. Human microRNAs miR-22, miR-138-2, miR-148a, and miR-488 are associated with panic disorder and regulate several anxiety candidate genes and related pathwaysBiol. [score:2]
[1 to 20 of 1 sentences]
23
[+] score: 2
The miR-381-3p, miR-548u, miR-411-5p, miR-148a-5p, and miR-96-5p which were filtered in HFD comparison but not in intact comparison and no-T2D comparison might involve the progress of T2D fed with HFD only. [score:1]
Among the 24 specific miRNAs, 13 of them, such as miR-182/196a/381/499a/99a [6], miR-183 [6, 23], miR-409 [23], miR-146b [6, 24], miR-143 [6, 24], miR-148a [24, 25], miR-204 [5], and miR-9 [6], have been reported to involve in T2D process in mouse or rat. [score:1]
[1 to 20 of 2 sentences]
24
[+] score: 1
Recent research showed that hypothalamus let-7, miR-148a, miR-124, miR-107 and miR-370 were confirmed to be related to EA tolerance (Cui et al., 2017). [score:1]
[1 to 20 of 1 sentences]
25
[+] score: 1
in the brain specimens and sixteen miRNAs (mir-192, mir-148a, mir-122, etc. ) [score:1]
[1 to 20 of 1 sentences]
26
[+] score: 1
MiRs-141-3p and 200c-3p appeared to increase prior to amylase or lipase in the 3 μg/kg group and displayed increases similar to amylase in the 15 and 45 μg/kg groups while miR-148a-3p displayed increases similar to amylase. [score:1]
[1 to 20 of 1 sentences]