2 publications mentioning lja-MIR171c

Open access articles that are associated with the species Lotus japonicus and mention the gene name MIR171c. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1

Thus, cytokinin signaling may have a dual mode for regulating NSP2 expression: it can directly activate NSP2 transiently and then repress its expression through activation of miR171 expression (Figure 1).

The regulatory mechanism for NSP2 expression is currently a vibrant area of research in plant–microbe interactions; recent evidence indicates that expression of NSP2 is negatively regulated by microRNA 171 (miR171; De Luis et al., 2012; Lauressergues et al., 2012).

Expression of miR171 is induced not only during nodule development but also by cytokinin in an MtCRE1 -dependent manner, and the expression pattern is negatively correlated with that of NSP2 (Ariel et al., 2012).

2

In both species, the specific miR171 isoforms studied were able to cleave the target transcript NSP2, a TF involved in NOD factor signaling.

The common function of miR171 isoforms in nodulation and mycorrhization reinforces the idea that nodule development may have evolved from AM fungi interactions though a diversification and specialization process.

More recently, a novel isoform of miR171 was discovered in M. truncatula and L. japonicus (Devers et al., 2011; Bazin et al., 2012; De Luis et al., 2012), that repress a key actor of symbiotic signaling, NSP2 (Nodulation Signaling Pathway 2, a GRAS TF).

Finally, the role of miR171 in legumes, first suggested by Devers et al. (2011), emerged through three different reports.

In L. japonicus, De Luis et al. (2012) showed that, similarly to miR397, the miR171c isoform accumulated in inoculated snf mutants and that this miRNA variant was associated to nodule establishment and maintenance but not organogenesis.

Lauressergues et al. (2012) and De Luis et al. (2012) showed that the miR171h and miR171c variants are fundamental to establish symbiotic mycorrhization and nodulation in M. truncatula and L. japonicus, respectively.

Further analyses of the miR171 family using both miRBase and comparative genomics (Bazin et al., 2012) revealed that this isoform is also present in non-legume species, such as Populus trichocarpa (ptc-miR171) and Citrus sinensis (csi-miR171b).