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2 publications mentioning ccr-mir-430

Open access articles that are associated with the species Cyprinus carpio and mention the gene name mir-430. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 32
The most abundant miRNAs in the present study were miR-430, miR-21, miR-22a, miR-181a, let-7a, miR-199-5p, miR-9-3p, miR-125b, miR-26a, miR-101a, miR-143, and miR-200a, which were not only co-expressed, but also significantly differentially expressed among the five different development stages in Yellow River carp. [score:6]
MiR-430-3p and miR-30-5p were the dominantly expressed conserved miRNAs in primordial germ cells, with >100,000 reads (Table  2), while ccr-miR-21 and ccr-let-7a were the dominantly expressed existing carp miRNAs in primordial gonads, with >10,000 reads (Table  3). [score:5]
The miR-430 family is known to be involved in embryonic morphogenesis and clearance of maternal mRNAs [60– 63], and miR-430 was significantly expressed in all five tested stages of Yellow River carp development. [score:4]
The miR-430 family was similarly highly expressed during early zebrafish development [61]. [score:4]
Expression of miR-430 decreased from the neurula stage to adult ovary (Fig.   4, profile 0). [score:3]
Among them, miR-430-3p, miR-19-3p, miR-143-3p, miR-202-5p, miR-30-5p, miR-122-5p, let-7-5p, miR-451-5p, miR-223-3p, and miR-216-5p were the highest-expressed miRNAs in the five periods. [score:3]
Overall, these results suggest that miR-430, miR-21, let-7, miR-181a, and miR-143 may play important roles in ovary differentiation and development in Yellow River carp. [score:2]
MiR-430 has been shown to target chemokine signaling to ensure accurate migration of primordial germ cells [64]. [score:2]
Fig. 9 Nucleotide bias at each position in novel miRNAs of Yellow River carp We verified the results of Solexa sequencing by quantitative real-time polymerase chain reaction (qRT-PCR) analysis of 10 randomly selected miRNAs, including five conserved miRNAs (ccr-miR-726, ccr-miR-181a, ccr-miR-200b, ccr-miR-196a, ccr-miR-430) and five novel miRNAs (novel-m4414-5p, novel-m0352-3p, novel-m3425-3p, novel-m1635-5p, novel-m0568-5p). [score:1]
Existing carp miRNAs were registered in miRBase of common carp, including 145, 139, 143, 143, and 145 existing carp miRNAs (i. e., miRNAs included in C. carpio miRBase) from the five libraries, respectively, of which miR-430, miR-21, let-7a, miR-199-5p, miR-9-3p, miR-22a, miR-125b, miR-26a, miR-181a, miR-101a, miR-143, and miR-200a were the most abundant (Additional file 3). [score:1]
The most abundant miRNAs in primordial gonads were miR-430, miR-21, let-7a, miR-199-5p, miR-9-3p, miR-22a, miR-125b, miR-26a, miR-181a, miR-101a, miR-143, and miR-200a with >10,000 reads each. [score:1]
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2
[+] score: 4
This result indicates that the mir-430 family might be fish specific. [score:1]
We looked for members of the mir-430 family in other animals and found that this family existed only in zebrafish, medaka and sea lamprey. [score:1]
Interestingly, three of the clusters contained miRNAs from the mir-430 family. [score:1]
Six miRNA families (mir-124, mir-9, mir-137, mir-7, mir-306 and let-7) were shared by both protostomes and deuterostomes; 17 miRNAs families were present only in vertebrates; and the remaining two miRNA families (mir-430 and mir-727) were identified only in fish and were possibly fish-specific miRNAs. [score:1]
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