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3 publications mentioning ccr-mir-133a

Open access articles that are associated with the species Cyprinus carpio and mention the gene name mir-133a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 43
Profiling of miRNAs expression in the common carp indicate that miR-1, miR-133a-3p, and miR-206 are specifically expressed in the muscle-rich tissues and organs (skeletal muscle, heart, gut) in the common carps, and that their expression increases with the progress of common carp muscle development, ultimately reaching their highest levels in the skeletal tissues of mature carp. [score:8]
It has been reported that a loss of Dicer function or a down-regulation of miR-1 and miR-133 in zebrafish alters muscle gene expression and disrupts actin organization during sarcomere assembly [32]. [score:6]
Although the carp-specific target genes of miR-1, miR-133, and miR-206 are not known, their specific expression pattern and high conservation indicate that they are also likely to play a role in the development of carp skeletal muscle. [score:6]
Of these, miR-1, miR-133a-3p, and miR-206, were found to be specifically expressed in heart, skeletal muscle, gut, eye, and skin (Fig. 4B), whereas miR-21, miR-26a, miR-181a-5p, and miR-222 were detected in all the samples with little expression level change. [score:5]
The results showed that miR-1, miR-133a-3p, and miR-206 were increased expression 48 hour post fertilization, and the other miRNAs were increased expression 7 day post hatching (Figure S3). [score:5]
And studies in vitro have shown that miR-1, miR-133, and miR-206 can target multiple muscle-development-related genes, including Fstl1, Utrn [50], HDAC4 [29], Pax7 [30], c-Met [31], [37], SRF [29]. [score:4]
The results showed that the expression of miR-1, miR-133a-3p, miR-206, and miR-21 was increased in the skeletal muscles from 30 day post-hatching to 2-year-old (Figure 5). [score:3]
Among four miRNAs, miR-1 and miR-133a-3p were expressed at significantly higher levels in the 2-year skeletal muscles than 1-year skeletal muscles (Figure 5). [score:3]
We then selected miR-1, miR-21, miR-23a, miR-24, miR-26a, miR-27a, miR-133a-3p, miR-181a-5p, miR-206, miR-214, and miR-222, which have been reported to play roles in the development of vertebrate skeletal muscle (Table 3). [score:2]
These results suggest that miR-1, miR-133a-3p, miR-21, miR-26, and miR-206 play roles in the growth and functional maintenance of carp skeletal muscles. [score:1]
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2
[+] score: 11
Gsdf was the predicted target of miR-132a, miR-146a, miR-210, miR-214, miR-22, and miR-22b; Hsd11b was predicted to target miR-1020-3p and miR-1187-3p; Hsd3b was the predicted target of miR-133-3p and miR-191-5p; Stat1 was predicted to be the target of miR-101a and miR-181a; Sf1 of miR-101b and miR-144; Sox9 of miR-15b and miR-16a; and atm was predicted to be the target of miR-132a and miR-181. [score:11]
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3
[+] score: 1
Among them, 21 were predicted novel miRNAs, while nine miRNAs (miR-196b, miR-365, miR-184, miR-153b, miR-301a, miR-133a-5p, miR-132b, miR-124a, miR-124b) were deposited in the miRbase database (Available online: http://www. [score:1]
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