miRNA Search Results

sort by 3 publications mentioning hsa-mir-4753 Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4753. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.
1	[+] score: 42 Other miRNAs from this paper: hsa-mir-20a, hsa-mir-197, hsa-mir-139, hsa-mir-126, hsa-mir-296, hsa-mir-369, hsa-mir-494, hsa-mir-520f, hsa-mir-505, hsa-mir-574, hsa-mir-586, hsa-mir-638, hsa-mir-877, hsa-mir-1225, hsa-mir-1238, hsa-mir-1915, hsa-mir-2861, hsa-mir-3162, hsa-mir-4307, hsa-mir-4312, hsa-mir-4281, hsa-mir-3665, hsa-mir-3940, hsa-mir-4455, hsa-mir-4466, hsa-mir-4484, hsa-mir-4505, hsa-mir-4516, hsa-mir-4530, hsa-mir-1587, hsa-mir-3960, hsa-mir-4687, hsa-mir-371b, hsa-mir-4787, hsa-mir-5001, hsa-mir-6068, hsa-mir-6069 Target gene prediction for the 2 down regulated miRNAs, miR-126-5p and miR-4753-3p depend on KEGG analysis. [score:4] The other down-regulated miRNA in chronic brucellosis was miR-4753-5p and only one study is present in press regarding its function. [score:4] Current study uniquely demonstrated the role of altered expression of miR-4753-5p in regulation of chronic brucellosis. [score:4] So, JAK-STAT and T cell receptor signaling pathways which are regulated by miR-126-5p and cytokine-cytokine receptor interaction which is targeted by both miR-126-5p and miR-4753-5p may be associated with CD8 T cell exhaustion. [score:4] In the present study we uniquely determined that reduced expression of miR-126-5p and miR-4753-5p were significantly associated with chronic brucellosis in human CD8+ T cells. [score:3] 0165138.g003 Fig 3miRNAs (miR-126-5p and miR-4753-3p) that are down-regulated in chronic group were considered common. [score:3] 0165138.g002 Fig 2Other decreased miRNA (miR-4753-3p) that target genes of immunologically effective pathways are shown in Fig 3. 10.1371/journal. [score:3] 0165138.g003 Fig 3 miRNAs (miR-126-5p and miR-4753-3p) that are down-regulated in chronic group were considered common. [score:3] 0165138.g002 Fig 2 Other decreased miRNA (miR-4753-3p) that target genes of immunologically effective pathways are shown in Fig 3. 10.1371/journal. [score:3] One of both mature miRNAs (miR-4753-5p) were differentially expressed in ASD relative to control in STS [87]. [score:3] Pathway Analysis of 2 down regulated miRNAs, miR-126-5p and miR-4753-3p according to KEGG function annotations. [score:2] According to KEGG pathways analysis, miR-4753-5p was linked to MAPK signaling pathway, endocytosis, regulation of actin cytoskeleton, calcium signaling pathway, focal adhesion, cytokine-cytokine receptor interaction, wnt signaling pathway, chemokine signaling pathways, protein processing in endoplasmic reticulum, phagosomes and ubiquitin mediated proteolysis. [score:2] In summary, KEGG pathways analysis of miR-126-5p and miR-4753-5p revealed that pathways related to these miRNAs in brucellosis have a most biological significance associated with the conversion of chronicity, including MAPK signaling pathway, cytokine-cytokine receptor interaction, endocytosis, regulation of actin cytoskeleton, focal adhesion and Wnt signaling pathways. [score:2] In the current study, 2 miRNAs (miR-126-5p and miR-4753-5p) were determined to display a significant fold change within chronic group in comparison with both the acute infection group and the control group. [score:1] Pathway Analysis of miR-4753-3p according to KEGG function annotations. [score:1] [1 to 20 of 15 sentences]
2	[+] score: 8 Other miRNAs from this paper: hsa-let-7f-1, hsa-let-7f-2, hsa-mir-138-2, hsa-mir-138-1, hsa-mir-195, hsa-mir-452, hsa-mir-4668, hsa-mir-3529, hsa-mir-5703, hsa-mir-892c, hsa-mir-6838, hsa-mir-6886 In the concrete case, miR-4753-3p is predicted to target 9,267 genes and miR-5703 to target 8,100 genes. [score:5] Given completely dissimilar seeds, the pair hsa-miR-5703 and hsa-miR-4753-3p for example yields a significant overlap of target genes (Jaccard index (JI) of 0.4; green box in the lower left part of Figure 3A). [score:3] [1 to 20 of 2 sentences]
3	[+] score: 3 Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-17, hsa-mir-20a, hsa-mir-21, hsa-mir-22, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-26a-1, hsa-mir-29a, hsa-mir-31, hsa-mir-32, hsa-mir-33a, hsa-mir-93, hsa-mir-98, hsa-mir-100, hsa-mir-101-1, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-106a, hsa-mir-198, hsa-mir-148a, hsa-mir-7-1, hsa-mir-7-2, hsa-mir-7-3, hsa-mir-181a-2, hsa-mir-187, hsa-mir-181a-1, hsa-mir-223, hsa-let-7g, hsa-let-7i, hsa-mir-122, hsa-mir-125b-1, hsa-mir-132, hsa-mir-141, hsa-mir-145, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-136, hsa-mir-146a, hsa-mir-150, hsa-mir-193a, hsa-mir-155, hsa-mir-29c, hsa-mir-200a, hsa-mir-101-2, hsa-mir-26a-2, hsa-mir-302c, hsa-mir-376c, hsa-mir-323a, hsa-mir-335, hsa-mir-451a, hsa-mir-485, hsa-mir-491, hsa-mir-193b, hsa-mir-526a-1, hsa-mir-526a-2, hsa-mir-576, hsa-mir-628, hsa-mir-650, hsa-mir-654, hsa-mir-216b, hsa-mir-1260a, hsa-mir-1275, hsa-mir-664a, hsa-mir-3145, hsa-mir-1260b, hsa-mir-323b, hsa-mir-4276, hsa-mir-3682, hsa-mir-4513, hsa-mir-451b, hsa-mir-664b, hsa-mir-5693 Furthermore, the in silico analysis performed by Khongnomnan et al. predicted another 75 miRNAs that might target viral genes of IAV, including miR-216b, miR-3682, miR-4513, miR-4753 and miR-5693 [76]. [score:3] [1 to 20 of 1 sentences]

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3 publications mentioning hsa-mir-4753

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4753. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 42

Target gene prediction for the 2 down regulated miRNAs, miR-126-5p and miR-4753-3p depend on KEGG analysis. [score:4]

The other down-regulated miRNA in chronic brucellosis was miR-4753-5p and only one study is present in press regarding its function. [score:4]

Current study uniquely demonstrated the role of altered expression of miR-4753-5p in regulation of chronic brucellosis. [score:4]

So, JAK-STAT and T cell receptor signaling pathways which are regulated by miR-126-5p and cytokine-cytokine receptor interaction which is targeted by both miR-126-5p and miR-4753-5p may be associated with CD8 T cell exhaustion. [score:4]

In the present study we uniquely determined that reduced expression of miR-126-5p and miR-4753-5p were significantly associated with chronic brucellosis in human CD8+ T cells. [score:3]

0165138.g003 Fig 3miRNAs (miR-126-5p and miR-4753-3p) that are down-regulated in chronic group were considered common. [score:3]

0165138.g002 Fig 2Other decreased miRNA (miR-4753-3p) that target genes of immunologically effective pathways are shown in Fig 3. 10.1371/journal. [score:3]

0165138.g003 Fig 3 miRNAs (miR-126-5p and miR-4753-3p) that are down-regulated in chronic group were considered common. [score:3]

0165138.g002 Fig 2 Other decreased miRNA (miR-4753-3p) that target genes of immunologically effective pathways are shown in Fig 3. 10.1371/journal. [score:3]

One of both mature miRNAs (miR-4753-5p) were differentially expressed in ASD relative to control in STS [87]. [score:3]

Pathway Analysis of 2 down regulated miRNAs, miR-126-5p and miR-4753-3p according to KEGG function annotations. [score:2]

According to KEGG pathways analysis, miR-4753-5p was linked to MAPK signaling pathway, endocytosis, regulation of actin cytoskeleton, calcium signaling pathway, focal adhesion, cytokine-cytokine receptor interaction, wnt signaling pathway, chemokine signaling pathways, protein processing in endoplasmic reticulum, phagosomes and ubiquitin mediated proteolysis. [score:2]

In summary, KEGG pathways analysis of miR-126-5p and miR-4753-5p revealed that pathways related to these miRNAs in brucellosis have a most biological significance associated with the conversion of chronicity, including MAPK signaling pathway, cytokine-cytokine receptor interaction, endocytosis, regulation of actin cytoskeleton, focal adhesion and Wnt signaling pathways. [score:2]

In the current study, 2 miRNAs (miR-126-5p and miR-4753-5p) were determined to display a significant fold change within chronic group in comparison with both the acute infection group and the control group. [score:1]

Pathway Analysis of miR-4753-3p according to KEGG function annotations. [score:1]

[1 to 20 of 15 sentences]

[+] score: 8

Other miRNAs from this paper: hsa-let-7f-1, hsa-let-7f-2, hsa-mir-138-2, hsa-mir-138-1, hsa-mir-195, hsa-mir-452, hsa-mir-4668, hsa-mir-3529, hsa-mir-5703, hsa-mir-892c, hsa-mir-6838, hsa-mir-6886

In the concrete case, miR-4753-3p is predicted to target 9,267 genes and miR-5703 to target 8,100 genes. [score:5]

Given completely dissimilar seeds, the pair hsa-miR-5703 and hsa-miR-4753-3p for example yields a significant overlap of target genes (Jaccard index (JI) of 0.4; green box in the lower left part of Figure 3A). [score:3]

[1 to 20 of 2 sentences]

[+] score: 3

Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-17, hsa-mir-20a, hsa-mir-21, hsa-mir-22, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-26a-1, hsa-mir-29a, hsa-mir-31, hsa-mir-32, hsa-mir-33a, hsa-mir-93, hsa-mir-98, hsa-mir-100, hsa-mir-101-1, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-106a, hsa-mir-198, hsa-mir-148a, hsa-mir-7-1, hsa-mir-7-2, hsa-mir-7-3, hsa-mir-181a-2, hsa-mir-187, hsa-mir-181a-1, hsa-mir-223, hsa-let-7g, hsa-let-7i, hsa-mir-122, hsa-mir-125b-1, hsa-mir-132, hsa-mir-141, hsa-mir-145, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-136, hsa-mir-146a, hsa-mir-150, hsa-mir-193a, hsa-mir-155, hsa-mir-29c, hsa-mir-200a, hsa-mir-101-2, hsa-mir-26a-2, hsa-mir-302c, hsa-mir-376c, hsa-mir-323a, hsa-mir-335, hsa-mir-451a, hsa-mir-485, hsa-mir-491, hsa-mir-193b, hsa-mir-526a-1, hsa-mir-526a-2, hsa-mir-576, hsa-mir-628, hsa-mir-650, hsa-mir-654, hsa-mir-216b, hsa-mir-1260a, hsa-mir-1275, hsa-mir-664a, hsa-mir-3145, hsa-mir-1260b, hsa-mir-323b, hsa-mir-4276, hsa-mir-3682, hsa-mir-4513, hsa-mir-451b, hsa-mir-664b, hsa-mir-5693

Furthermore, the in silico analysis performed by Khongnomnan et al. predicted another 75 miRNAs that might target viral genes of IAV, including miR-216b, miR-3682, miR-4513, miR-4753 and miR-5693 [76]. [score:3]

[1 to 20 of 1 sentences]

miRBase

3 publications mentioning hsa-mir-4753