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7 publications mentioning hsa-mir-4739

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-4739. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 10
MiRNA prediction tools included: miRanda [34], RNA22 [35], TargetScan [36], and MiRWalk [37] Combined with CD133 molecular regulation and human umbilical cord blood mononuclear cell s expressed miRNA two aspects of information, the final confirmation of the following 12 miRNA [19]: hsa-miR-29a-3p, hsa-miR-29b-3p, hsa-miR-200c-3p, hsa-miR-4423-5p, hsa-miR-335-3p, hsa-miR-142-3p, hsa-miR-142-5p, hsa-miR-22-3p, hsa-miR-30a-5p, hsa-miR-30e-5p, hsa-miR-377-3p and hsa-miR-4739 (Supplementary Table  2). [score:6]
Combined with CD133 molecular regulation and human umbilical cord blood mononuclear cells expressed miRNA two aspects of information, the final confirmation of the following 12 miRNA [19]: hsa-miR-29a-3p (Fig.   4A), hsa-miR-29b-3p (Fig.   4B), hsa-miR-200c-3p (Fig.   4C), hsa-miR-4423-5p (Fig.   4D), hsa-miR-335-3p (Fig.   4E), hsa-miR-142-5p (Fig.   4G), hsa-miR-22-3p (Fig.   4H), hsa-miR-30a-5p (Fig.   4I), hsa-miR-30e-5p (Fig.   4J), hsa-miR-377-3p (Fig.   4K) and hsa-miR-4739 (Fig.   4L) showed no difference between CD133+HUCB-MNC cells and CD133−HUCB-MNC cells. [score:4]
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2
[+] score: 7
Calcified valves significantly upregulated several miRNAs (miR-638, miR-4739, miR-4774-3p) and downregulated some miRNAs (miR-4492, miR-449c-5p, miR-1245b-3p, miR-6806-3p, miR-8087). [score:7]
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3
[+] score: 4
Interestingly, many of the genes containing such highly differentiated SNPs in the Alu-miRNA sites within their 3′UTRs (listed in Table 1) have target sites (encompassing these SNPs) for miRNAs that are primate-specific (miR-661 29, miR-1202 53), human-specific (miR-4739, miR-5095) 54, involved in the regulation of p53 signaling (miR-660 55, miR-661 29, miR-1285 56) or in the apoptosis pathway (miR-17 44 45, miR-30b 57, miR-106a-3p 45, miR-612 58). [score:4]
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4
[+] score: 3
Eleven miRNAs (miRNA-4530, miRNA-4739, miRNA-762, miRNA-4787-5p, miRNA-940, miRNA-3676-5p, miRNA-6090, miRNA-150-5p, miRNA-4516, miRNA-4284, miRNA-3656) demonstrated a similar expression trend in both the acute and chronic groups. [score:3]
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5
[+] score: 2
Only 7 of 11 miRNAs, including miR-33b-3p, miR-940, miR-4443, miR-4530, miR-4739, miR-486-5p, and miR-3960, were stably detected in all 4 groups (Figure 1). [score:1]
Figure 2Comparison of the serum levels of miR-33b-3p (A), miR-940 (B), miR-486-5p (C), miR-4443 (D), miR-3960 (E), miR-4530 (F), and miR-4739 (G) in subclinical hypothyroidism (SCH) + spontaneous abortion (SA), SCH, SA, and healthy control (HC) groups. [score:1]
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6
[+] score: 2
Three representative miRNAs (miR-4739, miR-1275, and miR-4298) potentially interact with multiple histone mRNAs, all of which form a conspicuously similar potential 3-way junction sxRNA structure. [score:1]
In some cases, the same miRNA was observed to associate with more than one histone mRNA and as depicted in Figures 3D,E, three of the miRNAs (miR-4739, miR-1275, and miR-4298) were predicted to interact with six different histone mRNAs, all of which form a conspicuously similar structure. [score:1]
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7
[+] score: 1
Other miRNAs from this paper: hsa-mir-338, hsa-mir-657, hsa-mir-761, hsa-mir-1250, hsa-mir-3065
Included among these SNPs was rs73410309 within the precursor sequence of MIR4739 located on chromosome 17q25.3 (OR = 1.1; p = 0.039), which is approximately 1.5 Mb from our top hit in MIR3065 (rs9913477) and not in high LD with this SNP (D’ = 0.007 and R [2] = 0.0) based on AFR 1000 Genomes reference panel [57]. [score:1]
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