sort by

1 publications mentioning eca-mir-454

Open access articles that are associated with the species Equus caballus and mention the gene name mir-454. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 19
Other miRNAs from this paper: eca-mir-133b, eca-mir-204b-2, eca-mir-486, eca-mir-374b
Although our down-regulated miRNAs, miR-133b and miR-454, are certainly not pregnancy specific, their down-regulation during pregnancy allows for an increase in the translation of numerous mRNAs, including X-linked RNA binding motif protein (RBMX) which is implicated in regulation of gene transcription and alternative splicing, as well as repairing double-stranded DNA breaks [28, 29] and DEAD (Asp-Glu-Ala-Asp) box helicase 6 (DDX6) which maintains adult progenitor cell function [30]. [score:10]
The other down-regulated miRNA (miR-454) was 12.9 X lower on average (range of 6.5–19.2 X). [score:4]
The number of predicted target mRNAs for each miRNA ranged from 59 (miR-486-5p) to 271 (miR-454; S2 File). [score:3]
Top twenty pathways predicted for miRNAs differentially regulated during pregnancy (miR-133b, miR-204b, miR-454, miR-486-5p). [score:2]
[1 to 20 of 4 sentences]