sort by

3 publications mentioning eca-mir-29a

Open access articles that are associated with the species Equus caballus and mention the gene name mir-29a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 36
The expression of maternally expressed gene 3 (MEG3), which is down-regulated in HCC, may be regulated by microRNA-29 low expression in tumor (LET) is also down-regulated in HCC and contributes to hypoxia -mediated invasionATB- lncRNA activated by TGF-β is highly expressed in HCC and strongly associated with poor prognosis in HCC patientsTherefore, the discovery of the impact of non-coding RNAs in HCC and CRC has led to useful applications in the clinical management of HCC, future treatment being represented by a cocktail of T-cell modulators and vaccines enriched with the molecular targets of blockers in cancer-signaling pathways [68, 89; 92- 97] In contrast to miRNAs, which were largely studied for their roles in carcinogenesis, lncRNAs are less described. [score:18]
The expression of maternally expressed gene 3 (MEG3), which is down-regulated in HCC, may be regulated by microRNA-29 low expression in tumor (LET) is also down-regulated in HCC and contributes to hypoxia -mediated invasionATB- lncRNA activated by TGF-β is highly expressed in HCC and strongly associated with poor prognosis in HCC patients Therefore, the discovery of the impact of non-coding RNAs in HCC and CRC has led to useful applications in the clinical management of HCC, future treatment being represented by a cocktail of T-cell modulators and vaccines enriched with the molecular targets of blockers in cancer-signaling pathways [68, 89; 92- 97] In contrast to miRNAs, which were largely studied for their roles in carcinogenesis, lncRNAs are less described. [score:18]
[1 to 20 of 2 sentences]
2
[+] score: 10
Consistent with the known role of miRNAs in the control of bone remo deling (for review see [8]) and their involvement in key regulation pathways of bone formation and remo deling such as BMP-signaling pathway (mir-133, mir-135) [51] and Wnt-signaling pathway (mir-29a) [52], miRNA predicted targets were found to be involved in the regulation of several signaling pathways (FGF, TGFb, IGF1). [score:5]
It has been shown that several miRNAs including mir-140, mir-199a, mir-193 and mir-29a/29b may be involved in cartilage anabolic and catabolic regulation by regulating the expression of key genes involved in those process such as MMP13, Adamts-5 or Col2A1 (for review see [39]). [score:5]
[1 to 20 of 2 sentences]
3
[+] score: 2
Other miRNAs have also been implicated in muscle development, including miR-26a (23), miR-27b (24), miR-29 (25), miR- 125b (26), miR-155 (27), miR-128a (28) and miR- 181 (29). [score:2]
[1 to 20 of 1 sentences]