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16 publications mentioning bta-mir-206

Open access articles that are associated with the species Bos taurus and mention the gene name mir-206. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 50
Other miRNAs from this paper: ssc-mir-122, ssc-mir-125b-2, ssc-mir-181b-2, ssc-mir-20a, ssc-mir-23a, ssc-mir-26a, ssc-mir-29b-1, ssc-mir-181c, ssc-mir-214, ssc-let-7c, ssc-let-7f-1, ssc-let-7i, ssc-mir-103-1, ssc-mir-107, ssc-mir-21, ssc-mir-29c, ssc-mir-30c-2, bta-mir-26a-2, bta-mir-29a, bta-let-7f-2, bta-mir-103-1, bta-mir-20a, bta-mir-21, bta-mir-26b, bta-mir-30d, bta-mir-499, bta-mir-99a, bta-mir-125b-1, bta-mir-126, bta-mir-181a-2, bta-mir-199a-1, bta-mir-30b, bta-mir-107, bta-mir-10a, bta-mir-127, bta-mir-142, bta-mir-181b-2, bta-mir-30e, bta-mir-92a-2, bta-let-7d, bta-mir-132, bta-mir-138-2, bta-mir-17, bta-mir-181c, bta-mir-192, bta-mir-199b, bta-mir-200a, bta-mir-200c, bta-mir-214, bta-mir-23a, bta-mir-29b-2, bta-mir-29c, bta-mir-455, bta-let-7g, bta-mir-10b, bta-mir-30a, bta-mir-200b, bta-let-7a-1, bta-let-7f-1, bta-mir-122, bta-mir-30c, bta-let-7i, bta-mir-25, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-103-2, bta-mir-125b-2, bta-mir-99b, ssc-mir-99b, ssc-mir-17, ssc-mir-30b, ssc-mir-199b, bta-mir-1-2, bta-mir-1-1, bta-mir-129-1, bta-mir-129-2, bta-mir-133a-2, bta-mir-133a-1, bta-mir-133b, bta-mir-135b, bta-mir-138-1, bta-mir-143, bta-mir-144, bta-mir-146b, bta-mir-146a, bta-mir-181d, bta-mir-190a, bta-mir-199a-2, bta-mir-202, bta-mir-211, bta-mir-212, bta-mir-223, bta-mir-26a-1, bta-mir-29d, bta-mir-30f, bta-mir-338, bta-mir-33a, bta-mir-33b, bta-mir-375, bta-mir-429, bta-mir-451, bta-mir-92a-1, bta-mir-92b, bta-mir-29e, bta-mir-29b-1, bta-mir-181a-1, bta-mir-181b-1, ssc-mir-133a-1, ssc-mir-1, ssc-mir-146b, ssc-mir-181a-1, ssc-mir-30a, bta-mir-199c, ssc-mir-206, ssc-let-7a-1, ssc-let-7e, ssc-let-7g, ssc-mir-133b, ssc-mir-29a, ssc-mir-30d, ssc-mir-30e, ssc-mir-199a-2, ssc-mir-499, ssc-mir-143, ssc-mir-10a, ssc-mir-10b, ssc-mir-103-2, ssc-mir-181a-2, ssc-mir-181b-1, ssc-mir-181d, ssc-mir-99a, ssc-mir-92a-2, ssc-mir-92a-1, ssc-mir-92b, ssc-mir-192, ssc-mir-142, ssc-mir-127, ssc-mir-202, ssc-mir-129a, ssc-mir-455, ssc-mir-125b-1, ssc-mir-338, ssc-mir-133a-2, ssc-mir-146a, bta-mir-26c, ssc-mir-30c-1, ssc-mir-126, ssc-mir-199a-1, ssc-mir-451, ssc-let-7a-2, ssc-mir-129b, ssc-mir-429, ssc-let-7d, ssc-let-7f-2, ssc-mir-29b-2, ssc-mir-132, ssc-mir-138, ssc-mir-144, ssc-mir-190a, ssc-mir-212, bta-mir-133c, ssc-mir-26b, ssc-mir-200b, ssc-mir-223, ssc-mir-375, ssc-mir-33b
Paula et al. (2017) showed that a short period of food restriction significantly increased the expression of miR-1, miR-206, miR-199, and miR-23a in fast muscle and significantly decreased the expression of miR-1 and miR-206 in slow muscle, while their targets (IGF-1 for miR-1, miR-206, and miR-199; mTOR for miR-199; and MFbx and PGC1a for miR-23a) exhibited negatively correlated expression profiles. [score:9]
Some muscle miRNAs have well-defined target genes, as miR-206 regulates IGF-1; miR-1, miR-122, and miR-462 control IGF-2a; the let-7 family regulates MSTN; miR-103 and miR-107 modulate GHR and FSHR; and miR-138 and miR-211 control LHR. [score:5]
miR-206 regulates the growth of the teleost tilapia (Oreochromis niloticus) through the modulation of IGF-1 gene expression. [score:4]
In tilapia, Yan et al. (2012a) and Nachtigall et al. (2015) showed that miR-1, miR-133a, and miR-206 have similar expression patterns in adult males and females and may assist each other to accurately control the development of skeletal muscles, although they perform distinct biological functions. [score:4]
In the skeletal muscle, the main edible part of the fish, miR-1, miR-133a, and miR-206 have conserved expression patterns in all farmed fish species, which makes them interesting molecules for modulating muscle development and growth. [score:4]
Therefore, miR-206 could affect tilapia growth by modulating IGF-1 gene expression levels (Yan et al., 2014). [score:3]
In addition, miR-206 loss of function in vivo was shown to significantly improve tilapia growth performance by targeting insulin-like growth factor-1 (IGF-1) (Yan et al., 2013b). [score:3]
They recorded changes in the expression levels of eight miRNAs (miR-1a, miR-181a, miR-133a, miR-214, miR-133b, miR-206, miR-146, and miR-26a) shown to be involved in a strong resumption of myogenesis (Zhu et al., 2014). [score:3]
Duran et al. (2015) analyzed the impact of the miRNA-target interactions of miR-1/ hdac4, miR-133-a/b/ srf, miR-206/ pax7, and miR-499/ sox6 in fast- and slow-twitch skeletal muscles during growth. [score:3]
Differential expression of microRNA-206 in skeletal muscle of female Piedmontese and Friesian cattle. [score:3]
The expression pattern of 12 miRNAs, including mir-1, mir-133 and mir-206, was validated by real time PCR. [score:3]
MiR-133a promotes, in part, myocyte proliferation by repressing serum response factor (SRF) (Chen et al., 2006), whereas miR-206 plays an important role in regulating the differentiation of C2C12 myoblasts in vitro (Kim et al., 2006). [score:2]
Muscle-specific microRNA miR-206 promotes muscle differentiation. [score:1]
For instance, the role ofmiR-1, miR-206, and miR-133 during myoblast proliferation and differentiation is recognized to interfere in the hypertrophic growth of skeletal muscle. [score:1]
MiR-1, miR-133a, miR-133b, miR-206, and miR-499 have been shown to be involved in the control of genes related to myoblast proliferation and differentiation. [score:1]
They found that miR-1 and miR-206 may promote myoblast differentiation in fast- and slow-twitch muscles in adult individuals, while miR-133a/b acts earlier, promoting myoblast proliferation in juveniles. [score:1]
[1 to 20 of 16 sentences]
2
[+] score: 45
Other miRNAs from this paper: bta-mir-29a, bta-let-7f-2, bta-mir-103-1, bta-mir-151, bta-mir-30d, bta-mir-320a-2, bta-mir-126, bta-mir-181a-2, bta-mir-27b, bta-mir-30b, bta-mir-31, bta-mir-34b, bta-mir-107, bta-mir-15b, bta-mir-181b-2, bta-mir-30e, bta-let-7d, bta-mir-124a-1, bta-mir-138-2, bta-mir-181c, bta-mir-214, bta-mir-455, bta-mir-93, bta-let-7g, bta-mir-10b, bta-mir-30a, bta-let-7a-1, bta-mir-487b, bta-let-7f-1, bta-mir-122, bta-mir-30c, bta-let-7i, bta-mir-25, bta-mir-34c, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-103-2, bta-mir-15a, bta-mir-34a, bta-mir-1-2, bta-mir-1-1, bta-mir-105b, bta-mir-124a-2, bta-mir-124b, bta-mir-133a-2, bta-mir-133a-1, bta-mir-133b, bta-mir-138-1, bta-mir-152, bta-mir-181d, bta-mir-196a-2, bta-mir-196a-1, bta-mir-30f, bta-mir-409a, bta-mir-432, bta-mir-486, bta-mir-495, bta-mir-543, bta-mir-9-1, bta-mir-9-2, bta-mir-1185, bta-mir-1271, bta-mir-181a-1, bta-mir-181b-1, bta-mir-2284i, bta-mir-2284s, bta-mir-2284l, bta-mir-2284j, bta-mir-2284t, bta-mir-2284d, bta-mir-2284n, bta-mir-2284g, bta-mir-2284p, bta-mir-2284u, bta-mir-2363-1, bta-mir-2363-2, bta-mir-2284f, bta-mir-2284a, bta-mir-2284k, bta-mir-2284c, bta-mir-2384, bta-mir-2284v, bta-mir-2284q, bta-mir-2404-1, bta-mir-2284m, bta-mir-2284b, bta-mir-320b, bta-mir-2424, bta-mir-2284r, bta-mir-2284h, bta-mir-2404-2, bta-mir-2284o, bta-mir-2284e, bta-mir-320a-1, bta-mir-424, bta-mir-2284w, bta-mir-2284x, bta-mir-409b, bta-mir-2284y-1, bta-mir-2284y-2, bta-mir-2284y-3, bta-mir-2284y-4, bta-mir-2284y-5, bta-mir-2284y-6, bta-mir-2284y-7, bta-mir-2284z-1, bta-mir-2284aa-1, bta-mir-2284z-3, bta-mir-2284aa-2, bta-mir-2284aa-3, bta-mir-2284z-4, bta-mir-2284z-5, bta-mir-2284z-6, bta-mir-2284z-7, bta-mir-2284aa-4, bta-mir-2284z-2, bta-mir-133c, bta-mir-2284ab, bta-mir-2284ac
Specifically, muscle-specific miR-206, which is directly activated by MyoD, can target sequences in the Fstl1 and Utrn gene and these sequences are sufficient to suppress gene expression in the presence of miR-206 [8]. [score:8]
Bone Morphogenetic Protein-2 (BMP-2), which is known to inhibit myogenesis, represses the expression of miR-206 by inhibiting its maturation process [11]. [score:7]
Although the bovine-specific target genes of miRNA-206, miRNA-1, miRNA-133, miRn12, and miRn17 are not known, their consistent expression pattern and high conservation indicate that they are also likely to play roles in the development of bovine muscle tissues. [score:6]
Comparison of miRNA expression profiles among tissues revealed that miR-2284x in liver, and miRNA-206, miRNA-1, miRNA-133, miRn12, and miRn17 in muscle-related tissue or organs (skeletal muscle, heart, intestines) were highly expressed (Figure 3). [score:5]
Based on stem-loop qPCR, 25 high-read miRNAs were detected, and the results showed that bta-miRNA-206, miRNA-1, miRNA-133, miRNAn12, and miRNAn17 were highly expressed in muscle-related tissue or organs, suggesting that these miRNAs may play a role in the development of bovine muscle tissues. [score:4]
Previous studies in vitro have shown that miR-1, miR-133, and miR-206 can target multiple muscle-development-related genes. [score:4]
Also, miR-1 and miR-206 regulate Pax7 directly. [score:3]
However, the expression levels of bta-miRNA-206, miRNA-1, and miRn17 did not change between day 90 bovine embryo and 2-year muscle tissues, but significantly increased in the calf muscle tissue (Figure 3). [score:3]
In beef cattle, miR-9 and miR-124 in the brain, miR-122 in the liver, and miR-1, miR-133a, and miR-206 in muscle are all tissue-specific [42]. [score:1]
The transcription of miR-206 is induced by MyoD, which promotes myogenic differentiation [10]. [score:1]
MiR-206, miR-1, and miR-133 are muscle specific miRNAs [9]. [score:1]
The largest miRNA family size identified was miR-2284, which consisted of 12 members, and let-7, miR-30, and miR-181/376 possessed 9, 7, and 4 members, respectively; whereas other miRNA families such as miR-1, miR-31, miR-93, and miR-206 had only one member (Additional file 1). [score:1]
This is similar to the results between bone morphogenetic proteins-2 (BMP-2) and miR-206 [11]. [score:1]
[1 to 20 of 13 sentences]
3
[+] score: 34
Other miRNAs from this paper: bta-mir-29a, bta-let-7f-2, bta-mir-27a, bta-mir-320a-2, bta-mir-99a, bta-mir-125a, bta-mir-181a-2, bta-mir-27b, bta-mir-10a, bta-mir-139, bta-mir-140, bta-mir-181b-2, bta-mir-487a, bta-let-7d, bta-mir-124a-1, bta-mir-181c, bta-mir-29b-2, bta-mir-29c, bta-mir-423, bta-let-7g, bta-mir-10b, bta-let-7a-1, bta-mir-487b, bta-let-7f-1, bta-mir-122, bta-let-7i, bta-mir-25, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-195, bta-mir-34a, bta-mir-1-2, bta-mir-1-1, bta-mir-124a-2, bta-mir-124b, bta-mir-133a-2, bta-mir-133a-1, bta-mir-133b, bta-mir-154a, bta-mir-181d, bta-mir-184, bta-mir-29d, bta-mir-335, bta-mir-33a, bta-mir-33b, bta-mir-486, bta-mir-495, bta-mir-95, bta-mir-9-1, bta-mir-9-2, bta-mir-29e, bta-mir-29b-1, bta-mir-1271, bta-mir-1249, bta-mir-181a-1, bta-mir-181b-1, bta-mir-2284i, bta-mir-2286, bta-mir-2300a, bta-mir-2300b, bta-mir-2284s, bta-mir-2284l, bta-mir-2284j, bta-mir-2284t, bta-mir-2284d, bta-mir-2319a, bta-mir-2319b, bta-mir-2284n, bta-mir-2284g, bta-mir-2329-1, bta-mir-2329-2, bta-mir-2284p, bta-mir-2284u, bta-mir-2363-1, bta-mir-2363-2, bta-mir-2284f, bta-mir-2284a, bta-mir-2284k, bta-mir-2284c, bta-mir-2284v, bta-mir-2396, bta-mir-2285c, bta-mir-2284q, bta-mir-2404-1, bta-mir-2284m, bta-mir-2284b, bta-mir-320b, bta-mir-2284r, bta-mir-2443, bta-mir-2284h, bta-mir-2450c, bta-mir-2450b, bta-mir-2450a, bta-mir-2404-2, bta-mir-2284o, bta-mir-2484, bta-mir-2284e, bta-mir-320a-1, bta-mir-2887-1, bta-mir-2887-2, bta-mir-2284w, bta-mir-3431, bta-mir-2284x, bta-mir-3432a-1, bta-mir-3432a-2, bta-mir-574, bta-mir-2284y-1, bta-mir-2284y-2, bta-mir-2284y-3, bta-mir-154c, bta-mir-154b, bta-mir-2284y-4, bta-mir-2284y-5, bta-mir-2284y-6, bta-mir-6526-1, bta-mir-6526-2, bta-mir-503, bta-mir-2284y-7, bta-mir-6526-3, bta-mir-2284z-1, bta-mir-2284aa-1, bta-mir-2284z-3, bta-mir-2284aa-2, bta-mir-2284aa-3, bta-mir-2284z-4, bta-mir-2284z-5, bta-mir-2284z-6, bta-mir-2284z-7, bta-mir-6536-1, bta-mir-2284aa-4, bta-mir-6536-2, bta-mir-2284z-2, bta-mir-133c, bta-mir-2284ab, bta-mir-2284ac, bta-mir-3432b, bta-mir-2450d
In addition, miR-206, miR-1, and miR-320 were up-regulated during MDSC differentiation; miR-495, miR-133b, and miR-487 were down-regulated in MDSC-D1 and upregulated in MDSC-D3. [score:10]
The results showed that miR-29a, miR-27a, and let-7i were highly expressed in MDSC-P; in contrast, miR-320, miR-1, and miR-206 were highly expressed in MDSC-D3. [score:5]
miR-1 and miR-206 were upregulated during satellite cell differentiation and promoted myogenesis [28, 33], whereas miR-133 was involved primarily in the promotion of proliferation [9]. [score:4]
The constant high-level expression at all stages after early differentiation suggested that the role of miR-206 was to repress functions associated with muscle precursor cells. [score:3]
The miRNA with the greatest count in MDSC-D3 was miR-206, a major miRNA in skeletal muscle development, with an average normalized read count of >1 million. [score:2]
For example, compared with the proliferation stages (MDSC-P), the expression levels of miR-2443, miR-423-5p, miR-181a, miR-10a, and miR-206 were higher in MDSC-D1, and the pattern was the same as that of miR-139, miR-1, miR-95, miR-206, and miR-133a in MDSC-D3. [score:2]
These data suggested that miR-1 plays different roles from miR-206 in muscle differentiation; miR-1 could affect the regulation of genes that require inactivation in later stages, while miR-206 could have a more constant role in repressing genes immediately after differentiation. [score:2]
Based on abundance levels, miR-206 and miR-1 were considered to have a greater role in MDSC differentiation than miR-133 or their targets could be more abundant. [score:2]
In addition, both miR-206 and miR-1 promoted differentiation [9], which suggested that these two miRNAs might have a greater effect than miR-133 in muscle satellite cell differentiation [35]. [score:1]
Combined with the facts that miR-206 was lowly abundant in proliferating cells of mouse C2C12 cells, and was reported to be induced during differentiation [34], we proposed that its presence was associated with the switch from precursor to mature muscle cell. [score:1]
For example, miR-1 and miR-206 could promote the differentiation of myoblasts, whereas miR-133 could promote cell proliferation [8– 10]. [score:1]
In this study, sequence comparison with known miRNAs identified the muscle-specific miR-206 as the most abundant miRNA across all MDSC samples, which represented more than 37.39 % of all miRNAs in MDSC-D3, and represented 10.15 % abundance in proliferating satellite cells. [score:1]
[1 to 20 of 12 sentences]
4
[+] score: 32
In the present study, miR-451 expression in the BP muscle of the grazing cattle was temporarily up-regulated at 2 mo compared to the housed cattle, which suggests the positive effect of grazing on miR-451 expression in skeletal muscles, as well as on miR-206 and miR-208b [16]. [score:7]
We recently reported that miR-206 and miR-208b expressions in the biceps femoris (BP) muscle of grazing Japanese Shorthorn cattle were elevated after 4 months of grazing; these miRNAs are associated with temporary down-regulation of MyoD and fast-type myosin heavy chain isoform [16], which could be associated with conversion of the bovine skeletal muscle type with miRNA profile [17]. [score:6]
Although miR-206 and miR-208b expression in the BP muscle of cattle was up-regulated by grazing [16], the unchanged muscle-specific miRNA levels in circulation in our study suggest that grazing is a mild form of exercise or movement for cattle that does not induce muscle damage. [score:6]
Although the effect of nutrition or movement during grazing could not be separately evaluated, the grazing of cattle in our previous study [16] resulted in significant up-regulation of miR-208b and down-regulation of miR-206, MyoD and MyHC-2x, which indicated that the skeletal muscle of the grazing cattle physiologically adapted to the increased movement. [score:5]
Recent studies of muscle-specific miRNAs such as miR-1, miR-133a/b, miR-206, and miR-208b have indicated their roles in the development or specification of skeletal muscle [5– 7]. [score:2]
MicroRNA-206 is overexpressed in the diaphragm but not the hindlimb muscle of mdx mouse. [score:2]
Serum levels of miR-1, miR-133a/b, and miR-206 are increased in patients of human Duchenne muscular dystrophy [18, 19] and of rhabdomyosarcoma tumor [20], and that the miR-21 level is affected in various types of cancers [21– 24]. [score:1]
Muscle-specific miRNAs such as miR-1, miR-133a, miR-206, miR-208b, and miR-499 were not significantly detected in the plasma exosomes across all samples (i. e., grazing and housed during experiment) except for miR-486 (0.18%) and a trace of miR-133b (< 0.001%). [score:1]
In the present study, among the 231 exosomal miRNAs detected in the cattle plasma, muscle-enriched miR-486 and a trace of miR133b were detected, but miR-1, miR-133a, miR-206, miR-208b, and miR-499 were not detected. [score:1]
Indeed, muscle-specific miR-1, miR-133a/b, miR-206, and/or miR-208b in circulation have been shown to be changed by muscle-damaging downhill walking [31] and marathon running in humans [39, 57]. [score:1]
[1 to 20 of 10 sentences]
5
[+] score: 27
Bone Morphogenetic Protein-2 (BMP-2), which is known to inhibit myogenesis, represses the expression of miR-206 by inhibiting its maturation process [7]. [score:7]
Comparison of miRNA expression profiles among tissues revealed that miR-154c in fat, and miRNA-1, miRNA-133 and miRNA-206 in muscle-related tissue or organs (skeletal muscle, heart) were specially expressed (Figure 5). [score:5]
In myocyte proliferation and differentiation, miR-206 was the first miRNA showed to play an important role in skeletal muscle development by regulating the expression of connexin43 in C2C12 cells, a gap junction protein required for skeletal myoblast fusion [5]. [score:5]
Previous studies have shown that miR-1, miR-133, and miR-206 can target multiple muscle development related genes. [score:4]
Also, miR-1 and miR-206 regulate Pax7 directly. [score:3]
In addition, the miR-206 gene is induced by MyoD, which promotes myogenic differentiation [6]. [score:1]
MiR-1 and miR-133, as well as miR-206, are all muscle specific miRNAs [8]. [score:1]
The contrastive patterns were shown by bta-miR-1, bta-miR-133a, bta-miR-378 and bta-miR-206 with 9799576, 18927, 24882 and 788710 reads in AM library as opposed to 89060, 127, 2209 and 28690 reads in AF library. [score:1]
[1 to 20 of 8 sentences]
6
[+] score: 23
One study suggested that the rapid removal of SNAI1 and SNAI2 at the onset of differentiation is mediated by miR-30a and miR-206, respectively, resulting in the upregulation of myogenin and a dependent increase in the miR-30a and miR-206 expression [31]. [score:6]
Dai et al. [27] confirmed the mechanism in which miR-1 and miR-206 positively regulate bovine skeletal muscle satellite cell myogenic differentiation via the downregulation of PAX7 and HDAC4. [score:5]
Moreover, miR-206 directly targets cyclin D1 (CCND1) and DNA polymerase α (POLA1), reducing the proliferation rate of myogenic cells [30]. [score:4]
MiR-1 and miR-206 were also found to inhibit PAX3 [28] and NOTCH3 [29] allowing differentiation to proceed. [score:3]
A few high-throughput studies have confirmed some of the identified miRNAs (miR-1, miR-128, miR-133a, miR-133b, miR-206, miR-222, and miR-503) as common for skeletal muscle development in mouse, human, pig, common carp [11], and cattle [25]. [score:2]
Cell culture experiments have shown that miR-1 and miR-206 promote muscle cell differentiation, whereas miR-133 enhances cell proliferation. [score:1]
It is plausible that in HER/LIM cells, the differentiation progression is accelerated via similar mechanisms involving miR-1, miR-133, miR-206, and myogenin, resulting possibly in enhanced myotube formation observed in the primary cultures of the skeletal muscle with a HER/LIM origin (Fig. 1). [score:1]
Moreover, some of identified molecules were also annotated as taking part in myoblast proliferation (miR-1, -128, -133a, -133b, -139, and -206); myocyte function (miR-31, -133a, -145, and -222); myoblast fusion (miR-206, -222, and -486); and satellite cell activation (miR-1 and -206) (Fig.   3). [score:1]
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7
[+] score: 18
In addition, skeletal muscle miR-206 and miR-208b expression is temporally upregulated, accompanying the downregulation of myosin heavy chain 2x expression, in grazing Japanese Shorthorn (JSH) cattle whereas the expression did not change in housed [7]. [score:13]
It was expected that grazing would shift the muscle properties toward slow-oxidative type and decreased adipogenicity, which is associated with expression of miR-206 [29, 30], miR-208b [31], and adipogenic genes such as PPARG2 [20, 21, 25]. [score:3]
Our previous studies revealed that skeletal muscle-specific miRNAs, namely miR-1, miR-133a/b, miR-206, miR-208a/b, miR-496, and miR-499, were abundant in the muscles of JB cattle [4], whereas none of them was detected in the plasma profiles except for a modest miR-486 content [24]. [score:1]
We also conducted qPCR of miRNAs that are enriched in muscle or plasma (miR-21-5p, miR-30d-5p, miR-103, miR-206, miR-208b, miR-451, miR-486, miR-499, miR-2412, and miR-2478), some of which are abundant in bovine skeletal muscles [4]. [score:1]
[1 to 20 of 4 sentences]
8
[+] score: 11
Chen et al. [13– 15] previously reported that miR-1 and miR-206 can promote the differentiation of skeletal muscle satellite cells and significantly inhibit their proliferation by decreasing the expression level of Pax7. [score:5]
We have identified several miRNAs that are up-regulated in MSTN [-/-] pigs, and these miRNAs have previously been shown to be involved in myoblast development, including the well-known miR-1, miR-206 [13, 15], and miR-486 [26] (Figure 1A). [score:5]
MiR-148a, miR-206 and miR-214 have been shown to be similar to miR-322/424 and miR-503 [12, 33, 34]. [score:1]
[1 to 20 of 3 sentences]
9
[+] score: 9
We have previously demonstrated that Piedmontese and Friesian female, but not male cattle showed differential expression of miR-206 in skeletal muscle leading to hypothesize a relationship between miRNA expression and sex [18]. [score:5]
In Texel sheep, the MSTN allele is characterized by a G vs A transition in the 3 [′]UTR that creates a target site for miR-1 and miR-206, which are highly expressed in skeletal muscle. [score:3]
Current data on the role of miRNAs in myogenesis has been obtained largely from studies on muscle-specific miR-1, miR-133 and miR-206. [score:1]
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It has been reported that muscle-specific miRNAs, miR-206 and miR-499, are upregulated and miR-1, miR-133a, and miR-133b are downregulated in extraocular muscles compared to limb muscle, concluding that a miRNA network contributes to the extraocular muscles by regulating posttranscriptional expression of genes involved in structure, signaling, metabolism, angiogenesis, myogenesis, and regeneration in extraocular muscles [7]. [score:9]
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[+] score: 7
In addition, the expression of myomiRs important in the myogenic process, which are induced during myoblast proliferation (i. e; miR-1, miR-206, miR-133a [18]), were significantly decreased in C2C12 grown in SEDM, confirming exit from the proliferation step and entrance in the differentiation process (Fig.   4). [score:3]
In addition, the expression of myomiRs important for the myogenic process and induced during myoblast proliferation (i. e; miR-1, miR-206, miR-133a) are significantly decreased in C2C12. [score:3]
Quantification of miR-1, miR-133a and miR-206 in C2C12, grown either in CM (white) or in EVs -depleted proliferation media (black). [score:1]
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Winbanks C. E. Wang B. Beyer C. Koh P. White L. Kantharidis P. Gregorevic P. TGF-β regulates miR-206 and miR-29 to control myogenic differentiation through regulation of HDAC4 J. Biol. [score:3]
McCarthy J. J. MicroRNA-206: The skeletal muscle-specific myomiR Biochim. [score:1]
Muscle-specific miRNAs, such as miR-1, miR-206 and miR-133a, contribute to myoblast differentiation [30, 31, 32, 33]. [score:1]
Kim H. K. Lee Y. S. Sivaprasad U. Malhotra A. Dutta A. Muscle-specific microRNA miR-206 promotes muscle differentiation J. Cell Biol. [score:1]
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[+] score: 4
Other miRNAs from this paper: bta-let-7f-2, bta-mir-101-2, bta-mir-103-1, bta-mir-21, bta-mir-27a, bta-mir-30d, bta-mir-320a-2, bta-mir-199a-1, bta-mir-27b, bta-mir-30b, bta-mir-107, bta-mir-140, bta-mir-30e, bta-let-7d, bta-mir-124a-1, bta-mir-199b, bta-mir-200a, bta-mir-200c, bta-let-7g, bta-mir-30a, bta-mir-200b, bta-let-7a-1, bta-let-7f-1, bta-mir-122, bta-mir-30c, bta-let-7i, bta-mir-25, bta-let-7a-2, bta-let-7a-3, bta-let-7b, bta-let-7c, bta-let-7e, bta-mir-103-2, bta-mir-1-2, bta-mir-1-1, bta-mir-101-1, bta-mir-124a-2, bta-mir-124b, bta-mir-133a-2, bta-mir-133a-1, bta-mir-143, bta-mir-152, bta-mir-154a, bta-mir-185, bta-mir-199a-2, bta-mir-30f, bta-mir-335, bta-mir-33a, bta-mir-33b, bta-mir-370, bta-mir-378-1, bta-mir-432, bta-mir-9-1, bta-mir-9-2, bta-mir-1224, bta-mir-376b, bta-mir-376d, bta-mir-376c, bta-mir-376a, bta-mir-1839, bta-mir-1185, bta-mir-2284i, bta-mir-2285a, bta-mir-2284s, bta-mir-2285d, bta-mir-2284l, bta-mir-2284j, bta-mir-2284t, bta-mir-2285b-1, bta-mir-2284d, bta-mir-2284n, bta-mir-2284g, bta-mir-199c, bta-mir-2284p, bta-mir-2284u, bta-mir-2363-1, bta-mir-2363-2, bta-mir-2284f, bta-mir-2284a, bta-mir-2284k, bta-mir-2284c, bta-mir-2284v, bta-mir-2285c, bta-mir-2284q, bta-mir-2284m, bta-mir-2284b, bta-mir-320b, bta-mir-2284r, bta-mir-2284h, bta-mir-2284o, bta-mir-2284e, bta-mir-320a-1, bta-mir-378-2, bta-mir-2284w, bta-mir-2284x, bta-mir-3432a-1, bta-mir-3432a-2, bta-mir-3604-1, bta-mir-3604-2, bta-mir-2284y-1, bta-mir-2285e-1, bta-mir-2285e-2, bta-mir-2285f-1, bta-mir-2285f-2, bta-mir-2285g-1, bta-mir-2285h, bta-mir-2285i, bta-mir-2285j-1, bta-mir-2285j-2, bta-mir-2285k-1, bta-mir-2285l, bta-mir-2285o-1, bta-mir-2285o-2, bta-mir-2285n-1, bta-mir-2285n-2, bta-mir-2285p, bta-mir-2285m-1, bta-mir-2285m-2, bta-mir-2284y-2, bta-mir-378b, bta-mir-2285n-3, bta-mir-2285n-4, bta-mir-2284y-3, bta-mir-154c, bta-mir-376e, bta-mir-154b, bta-mir-2285o-3, bta-mir-2285o-4, bta-mir-2285m-3, bta-mir-378c, bta-mir-2284y-4, bta-mir-2284y-5, bta-mir-2284y-6, bta-mir-2285m-4, bta-mir-2285o-5, bta-mir-2285m-5, bta-mir-2285n-5, bta-mir-2285n-6, bta-mir-6526-1, bta-mir-6526-2, bta-mir-503, bta-mir-2284y-7, bta-mir-6526-3, bta-mir-2285n-7, bta-mir-2284z-1, bta-mir-2284aa-1, bta-mir-2285k-2, bta-mir-2284z-3, bta-mir-2284aa-2, bta-mir-2284aa-3, bta-mir-2285k-3, bta-mir-2285k-4, bta-mir-2284z-4, bta-mir-2285k-5, bta-mir-2284z-5, bta-mir-2284z-6, bta-mir-2284z-7, bta-mir-6536-1, bta-mir-2284aa-4, bta-mir-6536-2, bta-mir-2285q, bta-mir-2285r, bta-mir-2285s, bta-mir-2285t, bta-mir-2285b-2, bta-mir-2285v, bta-mir-2284z-2, bta-mir-2285g-2, bta-mir-2285g-3, bta-mir-2285af-1, bta-mir-2285af-2, bta-mir-2285y, bta-mir-2285w, bta-mir-2285x, bta-mir-2285z, bta-mir-2285u, bta-mir-2285aa, bta-mir-2285ab, bta-mir-2284ab, bta-mir-2285ac, bta-mir-2285ad, bta-mir-2284ac, bta-mir-2285ae, bta-mir-378d, bta-mir-3432b, bta-mir-2285ag, bta-mir-2285ah, bta-mir-2285ai, bta-mir-2285aj, bta-mir-2285ak, bta-mir-2285al, bta-mir-2285am, bta-mir-2285ar, bta-mir-2285as-1, bta-mir-2285as-2, bta-mir-2285as-3, bta-mir-2285at-1, bta-mir-2285at-2, bta-mir-2285at-3, bta-mir-2285at-4, bta-mir-2285au, bta-mir-2285av, bta-mir-2285aw, bta-mir-2285ax-1, bta-mir-2285ax-2, bta-mir-2285ax-3, bta-mir-2285ay, bta-mir-2285az, bta-mir-2285an, bta-mir-2285ao-1, bta-mir-2285ao-2, bta-mir-2285ap, bta-mir-2285ao-3, bta-mir-2285aq-1, bta-mir-2285aq-2, bta-mir-2285ba-1, bta-mir-2285ba-2, bta-mir-2285bb, bta-mir-2285bc, bta-mir-2285bd, bta-mir-2285be, bta-mir-2285bf-1, bta-mir-2285bf-2, bta-mir-2285bf-3, bta-mir-2285bg, bta-mir-2285bh, bta-mir-2285bi-1, bta-mir-2285bi-2, bta-mir-2285bj-1, bta-mir-2285bj-2, bta-mir-2285bk, bta-mir-2285bl, bta-mir-2285bm, bta-mir-2285bn, bta-mir-2285bo, bta-mir-2285bp, bta-mir-2285bq, bta-mir-2285br, bta-mir-2285bs, bta-mir-2285bt, bta-mir-2285bu-1, bta-mir-2285bu-2, bta-mir-2285bv, bta-mir-2285bw, bta-mir-2285bx, bta-mir-2285by, bta-mir-2285bz, bta-mir-2285ca, bta-mir-2285cb, bta-mir-2285cc, bta-mir-2285cd, bta-mir-2285ce, bta-mir-2285cf, bta-mir-2285cg, bta-mir-2285ch, bta-mir-2285ci, bta-mir-2285cj, bta-mir-2285ck, bta-mir-2285cl, bta-mir-2285cm, bta-mir-2285cn, bta-mir-2285co, bta-mir-2285cp, bta-mir-2285cq, bta-mir-2285cr-1, bta-mir-2285cr-2, bta-mir-2285cs, bta-mir-2285ct, bta-mir-2285cu, bta-mir-2285cv-1, bta-mir-2285cv-2, bta-mir-2285cw-1, bta-mir-2285cw-2, bta-mir-2285cx, bta-mir-2285cy, bta-mir-2285cz, bta-mir-2285da, bta-mir-2285db, bta-mir-2285dc, bta-mir-2285dd, bta-mir-2285de, bta-mir-2285df, bta-mir-2285dg, bta-mir-2285dh, bta-mir-2285di, bta-mir-2285dj, bta-mir-2285dk, bta-mir-2285dl-1, bta-mir-2285dl-2, bta-mir-2285dm
In the muscle, bta-let-7a/b/f, bta-miR-1, and bta- miR-206 were the dominant expressed miRNAs, with more than 100,000 reads. [score:3]
In cattle, miR-9 and miR-124 in the brain, miR-122 in the liver, and miR-1, miR-133a, and miR-206 in muscle are all tissue-specific [27]. [score:1]
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The muscle-specific miR-1 was prominent in sirloin and heart -based preparations while miR-206, another muscle-specific miRNA, was prevalent in both raw and cooked sirloin. [score:1]
We also validated three miRNAs found at higher read counts in sirloin (miR-206), heart (miR-221-3p), and adrenal (miR-146b-5p). [score:1]
Sirloin contained the most abundant levels of miR-206, a well-studied and prominent skeletal muscle-specific miRNA [31], whereas heart tissue contained higher relative levels of miR-99a-5p and miR-100-5p. [score:1]
B) C [t] values for miR-206, miR-221-3p, and miR-146-5p across tissue and process groups. [score:1]
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A G > A transition in the 3ʹUTR of the GDF8 gene created microRNA target sites for mir1 and mir206, consequently promoting the muscular hypertrophy phenotype in Texel sheep [31]. [score:3]
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Recently, in vitro studies reported that certain miRNAs, such as miR-101a [22] and miR-126-3p [23], regulate the proliferation of mammary epithelial cells or, such as miR-206 [24], impact the development of this organ. [score:3]
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