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22 publications mentioning ssc-mir-16-1

Open access articles that are associated with the species Sus scrofa and mention the gene name mir-16-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 26
Similarly, expressions of miR-16 and miR-143 inhibit cell proliferation and suppress tumorigenesis, and miR-143 has been observed to be down-regulated in cervical cancer [36]. [score:10]
For bats, 3 out of 4 up-regulated miRNA (miR-101-3p, miR-16-5p, miR-143-3p) likely function as tumor suppressors against various kinds of cancers, while one down-regulated miRNA (miR-221-5p) acts as a tumorigenesis promoter in human breast and pancreatic cancers. [score:9]
The summary of the six DE miRNA common to all species is described in Fig.   5. Briefly, all DE candidates were single copy miRNA across all libraries, and 4 DE miRNA (miR-101-3p, miR-16-5p, miR-143-3p and miR-155-5p) were up-regulated in bats while 2 (miR-125-5p and miR-221-5p) were down-regulated. [score:7]
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2
[+] score: 20
Among them, let-7 g, miR-17-5p, miR-17-3p, miR-20a, miR-181a, miR-16, miR-146b, miR-10b, and miR-155-5p were upregulated; let-7c, miR-122, miR-18a, miR-19a, miR-19b, miR-196b, miR-21, and miR-9 were downregulated. [score:7]
However, we did not detect differential expression of other previously identified miRNAs (miR-223, miR-150, miR-92a), although miR-10b, miR-20a, miR-30a-5p, miR-34a, miR-17—5p, miR-16, miR-146b, and miR-155-5p expression was significantly different. [score:5]
The expression levels of ssc-miR-10b, ssc-miR-30a-5p, ssc-miR-16, ssc-miR-17-5p, and ssc-miR-192 in the PPV-infected cells were higher than in the uninfected cells, whereas ssc-miR-21, ssc-miR-19b, ssc-miR-18a, ssc-miR-152, and ssc-miR-novel-chr13_10861 were downregulated compared to the uninfected cells (Fig.   2). [score:5]
Let-7 g, let-7c, miR-19b, and miR-16 are involved in immune-related programs and may act through the target gene IL10. [score:3]
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3
[+] score: 15
In order to verification the differential expressed miRNAs, four down-regulated (let-7a, miR-16, miR-20a, miR-20b-5p) and 4 up-regulated miRNAs (miR-143, miR-192, miR-133b, miR-223) were randomly selected and analyzed using Real-time PCR method (Figure 6, A). [score:9]
miR-16 was shown to regulate liver cell line HepG2 apoptosis by targeting BCL2 gene [47], is also detected differential expression between the two breeds. [score:6]
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4
[+] score: 15
FAS has target sites for miR-195, miR-181d and miR-16 that were all downregulated in the liver of the obese minipigs. [score:6]
MiR-181d (FC 2.27; p value 0.03) was the most downregulated while miR-195 and miR-16 were down regulated with fold changes < -1.5 and p values < 0.05. [score:5]
MiR-208b-3p, miR-1, miR-16 and miR-195 were upregulated with a fold change of > 1.5 and p value < 0.05. [score:4]
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5
[+] score: 12
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-17, hsa-mir-18a, hsa-mir-19a, hsa-mir-19b-1, hsa-mir-20a, hsa-mir-22, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-98, hsa-mir-101-1, hsa-mir-16-2, mmu-let-7g, mmu-let-7i, mmu-mir-1a-1, mmu-mir-15b, mmu-mir-101a, mmu-mir-126a, mmu-mir-130a, mmu-mir-133a-1, mmu-mir-142a, mmu-mir-181a-2, mmu-mir-194-1, hsa-mir-208a, hsa-mir-30c-2, mmu-mir-122, mmu-mir-143, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-181a-1, mmu-let-7d, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-15b, hsa-mir-122, hsa-mir-130a, hsa-mir-133a-1, hsa-mir-133a-2, hsa-mir-142, hsa-mir-143, hsa-mir-126, hsa-mir-194-1, mmu-mir-30c-1, mmu-mir-30c-2, mmu-mir-208a, mmu-let-7a-1, mmu-let-7a-2, mmu-let-7b, mmu-let-7c-1, mmu-let-7c-2, mmu-let-7e, mmu-let-7f-1, mmu-let-7f-2, mmu-mir-15a, mmu-mir-16-1, mmu-mir-16-2, mmu-mir-18a, mmu-mir-20a, mmu-mir-22, mmu-mir-26a-1, mmu-mir-26b, mmu-mir-29c, mmu-mir-98, mmu-mir-326, rno-mir-326, rno-let-7d, rno-mir-20a, rno-mir-101b, mmu-mir-101b, hsa-mir-1-1, mmu-mir-1a-2, hsa-mir-181b-2, mmu-mir-17, mmu-mir-19a, mmu-mir-181a-1, mmu-mir-26a-2, mmu-mir-19b-1, mmu-mir-181b-1, mmu-mir-181c, hsa-mir-194-2, mmu-mir-194-2, hsa-mir-29c, hsa-mir-30c-1, hsa-mir-101-2, hsa-mir-26a-2, hsa-mir-378a, mmu-mir-378a, hsa-mir-326, mmu-mir-133a-2, mmu-mir-133b, hsa-mir-133b, mmu-mir-181b-2, rno-let-7a-1, rno-let-7a-2, rno-let-7b, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7f-1, rno-let-7f-2, rno-let-7i, rno-mir-15b, rno-mir-16, rno-mir-17-1, rno-mir-18a, rno-mir-19b-1, rno-mir-19a, rno-mir-22, rno-mir-26a, rno-mir-26b, rno-mir-29c-1, rno-mir-30c-1, rno-mir-30c-2, rno-mir-98, rno-mir-101a, rno-mir-122, rno-mir-126a, rno-mir-130a, rno-mir-133a, rno-mir-142, rno-mir-143, rno-mir-181c, rno-mir-181a-2, rno-mir-181b-1, rno-mir-181b-2, rno-mir-194-1, rno-mir-194-2, rno-mir-208a, rno-mir-181a-1, hsa-mir-423, hsa-mir-18b, hsa-mir-20b, hsa-mir-451a, mmu-mir-451a, rno-mir-451, ssc-mir-122, ssc-mir-15b, ssc-mir-181b-2, ssc-mir-19a, ssc-mir-20a, ssc-mir-26a, ssc-mir-326, ssc-mir-181c, ssc-let-7c, ssc-let-7f-1, ssc-let-7i, ssc-mir-18a, ssc-mir-29c, ssc-mir-30c-2, hsa-mir-484, hsa-mir-181d, hsa-mir-499a, rno-mir-1, rno-mir-133b, mmu-mir-484, mmu-mir-20b, rno-mir-20b, rno-mir-378a, rno-mir-499, hsa-mir-378d-2, mmu-mir-423, mmu-mir-499, mmu-mir-181d, mmu-mir-18b, mmu-mir-208b, hsa-mir-208b, rno-mir-17-2, rno-mir-181d, rno-mir-423, rno-mir-484, mmu-mir-1b, ssc-mir-15a, ssc-mir-16-2, ssc-mir-17, ssc-mir-130a, ssc-mir-101-1, ssc-mir-101-2, ssc-mir-133a-1, ssc-mir-1, ssc-mir-181a-1, ssc-let-7a-1, ssc-let-7e, ssc-let-7g, ssc-mir-378-1, ssc-mir-133b, ssc-mir-499, ssc-mir-143, ssc-mir-423, ssc-mir-181a-2, ssc-mir-181b-1, ssc-mir-181d, ssc-mir-98, ssc-mir-208b, ssc-mir-142, ssc-mir-19b-1, hsa-mir-378b, ssc-mir-22, rno-mir-126b, rno-mir-208b, rno-mir-133c, hsa-mir-378c, ssc-mir-194b, ssc-mir-133a-2, ssc-mir-484, ssc-mir-30c-1, ssc-mir-126, ssc-mir-378-2, ssc-mir-451, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, mmu-mir-378b, mmu-mir-101c, hsa-mir-451b, hsa-mir-499b, ssc-let-7a-2, ssc-mir-18b, hsa-mir-378j, rno-mir-378b, mmu-mir-133c, mmu-let-7j, mmu-mir-378c, mmu-mir-378d, mmu-mir-451b, ssc-let-7d, ssc-let-7f-2, ssc-mir-20b-1, ssc-mir-20b-2, ssc-mir-194a, mmu-let-7k, mmu-mir-126b, mmu-mir-142b, rno-let-7g, rno-mir-15a, ssc-mir-378b, rno-mir-29c-2, rno-mir-1b, ssc-mir-26b
let-7, miR-98, miR-130a and miR-16 showed uniform levels of expression in 13 different tissues but were hardly detected in pancreas (Figure 3A). [score:3]
Additionally, many other miRNAs, such as let-7, miR-98, miR-16, miR22, miR-26b, miR-29c, miR-30c and miR126, were also expressed abundantly in thymus (Figure 3). [score:3]
Similarly, let-7, miR-98, miR-16 and miR-130a are abundantly expressed in 13 of the 14 tissues (except in pancreas) (Figure 3A). [score:3]
Similarly, we found all members of the miR-15, miR-16, miR-18 and miR-133 families in our sequences, suggesting that all members belonging to these miRNA families are expressed in these three (heart, liver and thymus) tissues. [score:3]
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6
[+] score: 10
Secondly, targets for a sub-set of down-regulated miR (miR-15, miR-16, miR-27, miR-29, miR-34 and miR-106), of which 44 targets were identified based on our previous criteria were predicted (see Additional file 4). [score:8]
These miR have been implicated in multiple cellular processes including cell growth (miR-24), apoptosis (miR-16, miR-24 and miR-29), and cell cycle regulation in normal (miR-16) and cancerous cells (miR-24, miR-27, miR-29 and miR-34) [9, 40- 46]. [score:2]
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7
[+] score: 10
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-21, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-26a-1, hsa-mir-29a, hsa-mir-30a, hsa-mir-31, hsa-mir-99a, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-16-2, hsa-mir-192, hsa-mir-148a, hsa-mir-10b, hsa-mir-181a-2, hsa-mir-181a-1, hsa-mir-215, hsa-mir-223, hsa-mir-224, hsa-mir-200b, hsa-mir-15b, hsa-mir-27b, hsa-mir-125b-1, hsa-mir-141, hsa-mir-143, hsa-mir-152, hsa-mir-125b-2, hsa-mir-126, hsa-mir-146a, hsa-mir-184, hsa-mir-200c, hsa-mir-155, hsa-mir-29c, hsa-mir-200a, hsa-mir-99b, hsa-mir-296, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-378a, hsa-mir-342, hsa-mir-148b, hsa-mir-451a, ssc-mir-125b-2, ssc-mir-148a, ssc-mir-15b, ssc-mir-184, ssc-mir-224, ssc-mir-23a, ssc-mir-24-1, ssc-mir-26a, ssc-mir-29b-1, ssc-let-7f-1, ssc-mir-103-1, ssc-mir-21, ssc-mir-29c, hsa-mir-486-1, hsa-mir-499a, hsa-mir-671, hsa-mir-378d-2, bta-mir-26a-2, bta-mir-29a, bta-let-7f-2, bta-mir-103-1, bta-mir-148a, bta-mir-16b, bta-mir-21, bta-mir-499, bta-mir-99a, bta-mir-125b-1, bta-mir-126, bta-mir-181a-2, bta-mir-27b, bta-mir-31, bta-mir-15b, bta-mir-215, bta-mir-30e, bta-mir-148b, bta-mir-192, bta-mir-200a, bta-mir-200c, bta-mir-23a, bta-mir-29b-2, bta-mir-29c, bta-mir-10b, bta-mir-24-2, bta-mir-30a, bta-mir-200b, bta-let-7a-1, bta-mir-342, bta-let-7f-1, bta-let-7a-2, bta-let-7a-3, bta-mir-103-2, bta-mir-125b-2, bta-mir-15a, bta-mir-99b, hsa-mir-664a, ssc-mir-99b, hsa-mir-103b-1, hsa-mir-103b-2, ssc-mir-15a, ssc-mir-16-2, bta-mir-141, bta-mir-143, bta-mir-146a, bta-mir-152, bta-mir-155, bta-mir-16a, bta-mir-184, bta-mir-24-1, bta-mir-223, bta-mir-224, bta-mir-26a-1, bta-mir-296, bta-mir-29d, bta-mir-378-1, bta-mir-451, bta-mir-486, bta-mir-671, bta-mir-29e, bta-mir-29b-1, bta-mir-181a-1, ssc-mir-181a-1, ssc-mir-215, ssc-mir-30a, bta-mir-2318, bta-mir-2339, bta-mir-2430, bta-mir-664a, bta-mir-378-2, ssc-let-7a-1, ssc-mir-378-1, ssc-mir-29a, ssc-mir-30e, ssc-mir-499, ssc-mir-143, ssc-mir-10b, ssc-mir-486-1, ssc-mir-152, ssc-mir-103-2, ssc-mir-181a-2, ssc-mir-27b, ssc-mir-24-2, ssc-mir-99a, ssc-mir-148b, ssc-mir-664, ssc-mir-192, ssc-mir-342, ssc-mir-125b-1, oar-mir-21, oar-mir-29a, oar-mir-125b, oar-mir-181a-1, hsa-mir-378b, hsa-mir-378c, ssc-mir-296, ssc-mir-155, ssc-mir-146a, bta-mir-148c, ssc-mir-126, ssc-mir-378-2, ssc-mir-451, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-451b, hsa-mir-499b, ssc-let-7a-2, ssc-mir-486-2, hsa-mir-664b, hsa-mir-378j, ssc-let-7f-2, ssc-mir-29b-2, ssc-mir-31, ssc-mir-671, bta-mir-378b, bta-mir-378c, hsa-mir-486-2, oar-let-7a, oar-let-7f, oar-mir-103, oar-mir-10b, oar-mir-143, oar-mir-148a, oar-mir-152, oar-mir-16b, oar-mir-181a-2, oar-mir-200a, oar-mir-200b, oar-mir-200c, oar-mir-23a, oar-mir-26a, oar-mir-29b-1, oar-mir-30a, oar-mir-99a, bta-mir-664b, chi-let-7a, chi-let-7f, chi-mir-103, chi-mir-10b, chi-mir-125b, chi-mir-126, chi-mir-141, chi-mir-143, chi-mir-146a, chi-mir-148a, chi-mir-148b, chi-mir-155, chi-mir-15a, chi-mir-15b, chi-mir-16a, chi-mir-16b, chi-mir-184, chi-mir-192, chi-mir-200a, chi-mir-200b, chi-mir-200c, chi-mir-215, chi-mir-21, chi-mir-223, chi-mir-224, chi-mir-2318, chi-mir-23a, chi-mir-24, chi-mir-26a, chi-mir-27b, chi-mir-296, chi-mir-29a, chi-mir-29b, chi-mir-29c, chi-mir-30a, chi-mir-30e, chi-mir-342, chi-mir-378, chi-mir-451, chi-mir-499, chi-mir-671, chi-mir-99a, chi-mir-99b, bta-mir-378d, ssc-mir-378b, oar-mir-29b-2, ssc-mir-141, ssc-mir-200b, ssc-mir-223, bta-mir-148d
Similarly, Naeem et al. (2012) demonstrated a differential regulation of four miRNAs (Bta-miR-181a, miR-16, miR-31, and miR223) in bovine mammary tissue infected with Streptococcus uberis as compared to healthy tissue while Hou et al. (2012) showed that bta-miR-296, miR-2430, and miR-671 were up-regulated and miR-2318 was down-regulated in mammary tissues of cows with mastitis. [score:7]
Comparative analysis of the miRNA repertoire in lactating and non-lactating bovine and mouse mammary glands observed that 6 (miR-126-5p, miR-16-5p, miR-141-3p, miR-200a-3p, miR-200b-3p, miR-200c-3p) out of 24 miRNAs common to both species were highly expressed in lactating than non-lactating mammary glands (Le Guillou et al., 2014). [score:3]
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8
[+] score: 9
In the present study, we found that only miR-15a but not other miRNAs including miR-16, miR-21, and miR-34a, exhibited significant upregulation in the synchronized PCV2-infected PK15 cells. [score:4]
In contrast, miR-16 expression levels were not obviously changed after PCV2 infection, comparable to that in mock-infected cells (Fig. 4). [score:3]
Synchronized PK15 cells were mock infected or infected with PCV2 at an MOI of 1. At 24 h postinfection, expression levels of miR-15a and miR-16 as well as miR-21 and miR-34a were assayed by qRT-PCR. [score:2]
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9
[+] score: 8
Further studies demonstrated that miR-15a, miR-16-1, as well as miR-195 were important regulators of the cell cycle by targeting BCL2, DLEU2 [45], [46]. [score:4]
Bottoni reported that miR-15a and miR-16-1 were down-regulated in pituitary adenomas [44]. [score:4]
[1 to 20 of 2 sentences]
10
[+] score: 7
In accordance with the most stable miRNAs described in the literature [20]– [22], [24], [26]– [28], ten candidate miRNAs (Ssc-let-7a, Ssc-miR-103, Ssc-miR-17-3p, Hsa-miR-25, Hsa-miR-93, Ssc-miR-106a, Ssc-miR-191, Ssc-miR-16, Ssc-miR-26a and Ssc-miR-17-5p, Table 1) were selected to study their expression stability in different porcine tissues and breeds. [score:3]
Conversely, miR-16 was the least stable miRNA in kidney, uterus and liver, miR-103 in ovary and miR-17-3p in skeletal muscle. [score:1]
curve correlation mean * Ssc-let-7a 125 1/2000 95.52% (2.11%) 0.9991 (0.0005) Ssc-miR-103 250 1/2000 96.27% (5.15%) 0.9981 (0.0013) Ssc-miR-17-3p 250 1/200 99.96% (7.25%) 0.9971 (0.0026) Hsa-miR-25 250 1/2000 97.14% (3.76%) 0.9989 (0.0004) Hsa-miR-93 200 1/2000 98.10% (3.12%) 0.9973 (0.0012) Ssc-miR-106a 250 1/2000 99.73% (11.05%) 0.9978 (0.0015) Ssc-miR-191 250 1/2000 97.45% (3.91%) 0.9978 (0.0009) Ssc-miR-16 250 1/2000 98.31% (4.98%) 0.9990 (0. 0004) Ssc-miR-26a 250 1/2000 93.35% (0.62%) 0.9991 (0.0005) Ssc-miR-17-5p 250 1/2000 98.52% (5.00%) 0.9980 (0.0009) * The numbers in brackets denote the standard error for the mean values. [score:1]
The least stable miRNAs were miR-191 in Iberian and Landrace breeds, miR-16 in Large White and Vietnamese breeds and miR-26a in Meishan breed (data not shown). [score:1]
Despite of these discordances, miR-17-5p (M = 0.69, SV = 0.32) was well ranked in both studies and miR-16 (M = 0.78, SV = 0.41) had discrete M and SV values in the two studies. [score:1]
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11
[+] score: 6
PTr2 expressed all 14 miRNAs and miR-16, miR-17-5P, miR-15b, let-7f, and miR-20a were found in greater abundance (Fig. 4a). [score:3]
Among these, miR-16, miR-17-5P, let-7f, miR-126-5P, and miR-296-5P were relatively abundant. [score:1]
In PTr2 cells, miR-16, miR-17-5P, miR-15b, let-7f, and miR-20a were relatively abundant. [score:1]
Among these, miR-16, miR-17-5P, let-7f, miR-126-5P, and miR-296-5P were relatively abundant (Fig. 4b). [score:1]
[1 to 20 of 4 sentences]
12
[+] score: 6
In our study, prv-miR-6, prv-miR-15, prv-miR-16, prv-miR-LLT-1, prv-miR-LLT-7, prv-miR-LLT-9 and prv-miR-LLT-11 are predicted to target the 3’ UTR of the PRV trans-activator IE180. [score:3]
prv-miR-5, prv-miR-15, prv-miR-16, prv-miR-17, prv-miR-22, prv-miR-23, prv-miR-25, prv-miR-LLT-1, prv-miR-LLT-3, prv-miR-LLT-7, prv-miR-LLT-8 and prv-miR-LLT-11 were predicted to target the LLT region that serves as the large latency transcript of the PRV. [score:3]
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13
[+] score: 5
According to the high-throughput sequencing data, the let-7 family (let-7a, let-7f, let-7 g), the miR-10 family (miR-10b, miR-10a-3p, miR-10a-5p), miR-21, miR-143-3p, miR-30a-5p, miR-16 and miR-192 had the highest expression levels among the 10 expression profiles (Additional file  1: Figure S3), which suggests that these miRNAs are highly conserved among different organs in the same species. [score:5]
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14
[+] score: 4
Conserved miRNAs showed comparable expression patterns and clustering revealed consistency between both approaches, e. g. miR-126, miR-24 and miR-22 were combined in the same cluster and together with miR-16, miR-21 and let-7d showed increased expression in colon compared with other loci (Figure 4). [score:4]
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15
[+] score: 4
For example, miR-15 and miR-16 were found to be down-regulated in pituitary adenomas and correlated with the secretion of P43, a precursor of the inflammatory cytokine endothelial monocyte-activating polypeptide II [29]. [score:4]
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16
[+] score: 3
Another four miRNAs (mmu-miR-34b, mmu-miR-122a, mmu-miR-16 and mmu-miR-101) were confirmed to be differentially expressed in mouse testes by using conventional Northern blot analysis [2]. [score:3]
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17
[+] score: 3
12946) miR-16-5p Potential regulator of SMAD3 102 1.23E-24 −9.938 Li et al. 2015 (10.2174/1381612821666150909094712) miR-1-3p Unknown 99 5.58E-24 −9.767 n/a let-7a-5p Potential regulator of CCND1 and MYC 78 7.77E-20 −8.622 Ghanbari et al. 2015 (10.4137/BIC. [score:3]
[1 to 20 of 1 sentences]
18
[+] score: 2
Total RNA of the fresh maize or porcine tissues and serum was extracted using Trizol Reagent or Trizol LS Reagent (Invitrogen), and synthetic ssc-miR-16, zma-miR164a-5p, zma-miR167e-5p, zma-miR168a-5p, zma-miR319a-3p and zma-miR-408a-3p (with or without 2′-O-methyl) were obtained from RiboBio. [score:1]
Consequently, while the endogenous porcine miRNAs (ssc-miR-16, ssc-miR-24 and ssc-miR-25) were completely degraded (Fig.   2B and Supplementary Fig.   S2B,C), the maize-derived miRNAs (zma-miR164a-5p, zma-miR167e-5p, zma-miR168a-5p, zma-miR319a-3p and zma-miR408a-3p) exhibited similar abundance to synthetic miRNA with 2′-O-methylated 3′ ends, implying resistance to periodate oxidation, and thus were bona fide plant miRNAs (Fig.   2C–G). [score:1]
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19
[+] score: 1
Expression data were analyzed using the GenEx Pro Software (Multid Analyses AB, Göteborg, Sweden): Cq values were normalized to the geometric mean of the reference genes (HPRT, RPL4, and TBP for mRNAs and let7a and miR-16 for microRNAs) and the average was calculated for each pair of cDNA replicates. [score:1]
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20
[+] score: 1
After evaluation of its stability by geNorm v3.5 algorithm [36], five miRNAs (ssc-miR-26a, ssc-let-7a, ssc-miR-103, ssc-miR-17-5p and ssc-miR-16-5p) were used as reference to normalize expression [37]. [score:1]
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However, the highest number of significantly regulated miRNAs compared to before challenge was found at 14d pi, at which time point the infection had completely cleared (ssc-miR-15a, ssc-miR-29b, ssc-miR-29a, hsa-miR-449a, ssc-miR-186, ssc-miR-22-5p, ssc-miR-28-5p, hsa-miR-203a-3p, ssc-miR-146a-5p, hsa-miR-150-5p, ssc-miR-23b, hsa-miR-223-3p, hsa-miR-23a-3p, hsa-miR-16-5p). [score:1]
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Guo C. J. Pan Q. Li D. G. Sun H. Liu B. W. miR-15b and miR-16 are implicated in activation of the rat hepatic stellate cell: An essential role for apoptosisJ. [score:1]
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