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6 publications mentioning mml-let-7a-1

Open access articles that are associated with the species Macaca mulatta and mention the gene name let-7a-1. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 11
Down-regulation of Lin28 mRNA is accompanied with up-regulation of let-7 miRNA family, and this regulatory axis dynamics is required for ESC differentiation as well as commitment to neural fate. [score:8]
Inversely, the expression levels of most Let-7 family members (let-7a, 7c, 7e, 7f, 7g, and miR-98) increase gradually from ESC to R-NSCP6 (Fig.   4A). [score:3]
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[+] score: 8
Among others, such as hsa-miR-191, hsa-miR-200b, hsa-miR-320 and several members of let-7 family we found that hsa-miR-342-3p was regulated at a late stage of disease in both, Scrapie-infected mice and BSE-infected macaques. [score:4]
We excluded those miRNAs from further analysis showing divergent endogenous expression levels as compared to human brain, e. g. hsa-miR-103 and -107 (additional file 2) and the abundantly expressed members of the let-7 family. [score:4]
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[+] score: 7
Additionally, some members of let-7 family were upregulated in rpESCs. [score:4]
Oncogenic miRNAs [37], [38], including let-7 family, miR-374 family, miR-138, miR-195, miR-19a and miR-200a, had more than twice expression level in rpESCs comparing with their IVF counterparts. [score:3]
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[+] score: 6
In vitro LPS treatment but not prior in vivo exposures was a significant source of variation for miR-let-7a expression with significantly increased miR-let-7a levels in ozone-exposed animals following LPS treatment in vitro (Figure 5D; p = 0.001; two-way ANOVA for in vivo exposure and in vitro LPS treatment). [score:3]
miR-let-7a was also included in the analysis as it is a known functional modulator of IL-6 expression [34]. [score:3]
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[+] score: 1
MiRNAs reportedly unaffected by TRIzol extraction include those from the let-7 family, hsa-miR-200c-3p, -29a-3p, and -25-3p. [score:1]
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[+] score: 1
MiR-let-7a, miR-7, miR-9, miR-513 and miR-220 families contain three or more copies distributed on the same or different chromosomes that produce identical or slightly differed mature miRNAs. [score:1]
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