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14 publications mentioning hsa-mir-1266

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1266. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

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[+] score: 25
miRNA Tissue type Mode of action Reference miR-491-5p Cervical cancerUnknown, inhibits hTERT Zhao et al., 2015 miR-1182 Gastric cancerBinds the ORF of hTERT mRNA, preventing translation Zhang et al., 2015 miR-1207-5p Gastric cancerRepresses hTERT in normal tissues Chen et al., 2014 miR-1266 Gastric cancerRepresses hTERT in normal tissues Chen et al., 2014 miR-138 Anaplastic thyroid carcinoma (ATC)Interaction with 3′UTR of hTERT to reduce protein expression Mitomo et al., 2008 let-7g Pulmonary fibrosisInteraction with 3′UTR of hTERT to reduce expression Singh et al., 2010 miR-133a Jurkat cellsInteraction with 3′UTR of hTERT to reduce expression Hrdličková et al., 2014 miR-342 Jurkat cellsInteraction with the 3′UTR of hTERT to reduce expression Hrdličková et al., 2014 miR-541 Jurkat cellsInteraction with the 3′UTR of hTERT to reduce expression Hrdličková et al., 2014 Non-coding RNAs can also target transcription factors involved in the control of hTERT. [score:17]
miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase. [score:5]
miR-1207-5p and miR-1266 also target hTERT within gastric cancers, and are significantly repressed in gastric cancer tissue samples (Chen et al., 2014). [score:3]
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[+] score: 11
We observed differing expression of miR-224 and miR-383, whereas expression of the five other candidate miRNAs: miR-610, miR-637, miR-659, miR-1202 and miR-1266 did not differ significantly between ccRCC and control tissue (Figure S1, Supplemental Data). [score:5]
Expression of miR-224, miR-383, miR-610, miR-637, miR-659, miR-1202 and miR-1266 was analyzed in 32 matched pairs of tumor (T) and control (C) samples. [score:3]
We identified 7 potential miRNAs targeting the 3′UTR of human DIO1 (Table 1): miR-224, miR-383, miR-610, miR-659, miR-637, miR-1202 and miR-1266. [score:3]
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[+] score: 11
Furthermore, these 34 target-mRNAs were regulated by hsa-mir-29a, hsa-mir-29b, hsa-mir-29c, hsa-mir-452 and hsa-mir-1266, and were all related to neuronal development, neurodegenerative diseases and aging-related disorders. [score:7]
Hsa-mir-1266’s target site spans the rs27072 SNP locus, which was significantly associated with bipolar disorder [51]. [score:3]
For example, miRNA clique 103 (Figure  7) consisted of six miRNAs: hsa-mir-29a, hsa-mir-29b, hsa-mir-1255a, hsa-mir-1266, hsa-mir-452 and hsa-mir-29c. [score:1]
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[+] score: 9
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-17, hsa-mir-18a, hsa-mir-20a, hsa-mir-21, hsa-mir-22, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-27a, hsa-mir-29a, hsa-mir-30a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-93, hsa-mir-101-1, hsa-mir-106a, hsa-mir-107, hsa-mir-16-2, hsa-mir-192, hsa-mir-196a-1, hsa-mir-199a-1, hsa-mir-129-1, hsa-mir-148a, hsa-mir-10b, hsa-mir-34a, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-196a-2, hsa-mir-199a-2, hsa-mir-203a, hsa-mir-210, hsa-mir-212, hsa-mir-214, hsa-mir-215, hsa-mir-217, hsa-mir-218-1, hsa-mir-218-2, hsa-mir-221, hsa-mir-222, hsa-mir-223, hsa-mir-200b, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-15b, hsa-mir-27b, hsa-mir-122, hsa-mir-124-1, hsa-mir-124-2, hsa-mir-124-3, hsa-mir-125b-1, hsa-mir-130a, hsa-mir-141, hsa-mir-142, hsa-mir-143, hsa-mir-145, hsa-mir-153-1, hsa-mir-153-2, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-129-2, hsa-mir-146a, hsa-mir-150, hsa-mir-185, hsa-mir-195, hsa-mir-206, hsa-mir-200c, hsa-mir-1-1, hsa-mir-155, hsa-mir-181b-2, hsa-mir-106b, hsa-mir-29c, hsa-mir-200a, hsa-mir-101-2, hsa-mir-34b, hsa-mir-34c, hsa-mir-130b, hsa-mir-376c, hsa-mir-375, hsa-mir-378a, hsa-mir-148b, hsa-mir-338, hsa-mir-335, hsa-mir-423, hsa-mir-20b, hsa-mir-429, hsa-mir-449a, hsa-mir-433, hsa-mir-451a, hsa-mir-193b, hsa-mir-520d, hsa-mir-503, hsa-mir-92b, hsa-mir-610, hsa-mir-630, hsa-mir-650, hsa-mir-449b, hsa-mir-421, hsa-mir-449c, hsa-mir-378d-2, hsa-mir-744, hsa-mir-1207, hsa-mir-378b, hsa-mir-378c, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-4512, hsa-mir-378i, hsa-mir-203b, hsa-mir-451b, hsa-mir-378j
Chen L. Lu M. H. Zhang D. Hao N. B. Fan Y. H. Wu Y. Y. Wang S. M. Xie R. Fang D. C. Zhang H. miR-1207–5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptase Cell Death Dis. [score:5]
miR-1207-5p and miR-1266 are significantly down-regulated in GC tissues. [score:4]
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[+] score: 8
Chen et al (12) determined that miR-1207-5p and miR-1266 interact with the 3′UTR of hTERT and suppress gastric cancer growth and invasion by targeting hTERT. [score:5]
Three different miRNAs (miR138 in human anaplastic thyroid carcinoma cell lines, miR-1207 and miR1266 in gastric cancer) have been identified that may influence hTERT expression (12, 13). [score:3]
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[+] score: 7
In this respect, the miRNAs targeting telomerase directly or indirectly, might serve as tumor suppressive genes in cellular processes, such as let-7g, miR-138, miR-1207 and miR-1266, which induced tumor senescence and death eventually [15– 17]. [score:7]
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[+] score: 6
Recent studies demonstrated that miR-138, miR-133a, miR-342, miR-491-5p, miR-541, miR-1207-5p, miR-1266 and miR-1182 control hTERT expression in leukemic T-cell lymphoblasts, gastric cancer, cervical cancer, thyroid carcinoma and head and neck squamous cell carcinoma [28– 31, 33]. [score:3]
Recent studies reported a role of miR-133a, miR-138, miR-541, miR-491-5p, miR-512-5p, miR-1182, miR-1207-5p and miR-1266 in the control of hTERT expression in various types of cancer cells [27– 33]. [score:3]
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[+] score: 5
It was demonstrated that miR-1207-5p and miR-1266 could suppress gastric cancer growth and invasion by targeting the telomerase reverse transcriptase (hTERT) (Chen et al., 2014). [score:5]
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9
[+] score: 5
Other miRNAs from this paper: hsa-mir-483, hsa-mir-615, hsa-mir-1207
Chen L miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptaseCell Death Dis. [score:5]
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[+] score: 5
Chen L. Lü M. H. Zhang D. Hao N. B. Fan Y. H. Wu Y. Y. Wang S. M. Xie R. Fang D. C. Zhang H. Hu C. J. miR-1207-5p and miR-1266 suppress gastric cancer growth and invasion by targeting telomerase reverse transcriptaseCell Death Dis. [score:5]
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11
[+] score: 4
Specifically, miR-1182, miR-1207-5p, miR-1266, miR-532 and miR-3064, which bind within the h TERT 3’UTR, are downregulated and associated with a poor clinical outcome in bladder, gastric and ovarian cancer [169– 171]. [score:4]
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12
[+] score: 2
1000507.g004 Figure 4Screenshots of the UCSC Genome Browser [48] displaying RefSeq genes (blue lines with hatch marks), miRNA hairpins (red blocks), snoRNAs (green blocks with hatch marks), repeat-elements (blue blocks with hatch marks) and TSDs (black blocks) are shown for the genomic regions surrounding mir-215 (A), mir-549 (B), mir-1266 (C) and mir-605 (D). [score:1]
Screenshots of the UCSC Genome Browser [48] displaying RefSeq genes (blue lines with hatch marks), miRNA hairpins (red blocks), snoRNAs (green blocks with hatch marks), repeat-elements (blue blocks with hatch marks) and TSDs (black blocks) are shown for the genomic regions surrounding mir-215 (A), mir-549 (B), mir-1266 (C) and mir-605 (D). [score:1]
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13
[+] score: 1
miR-122-5p and miR-1266-5p were the only miRNAs with ratios < 2 in all samples and had the lowest standard deviations of all miRNAs tested (Additional file 1: Table S1). [score:1]
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14
[+] score: 1
The high serum level of miR-1266 was observed in patients with psoriasis, highlighting its potential use as a biomarker [18]. [score:1]
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