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12 publications mentioning hsa-mir-1202

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-1202. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 23
We found 37 differentially expressed miRNAs in the CD133 [+] spheroid-forming subpopulation of OVCAR3 cells, 34 of which were significantly up-regulated, including miR-205, miR-146a, miR-200a, miR-200b, and miR-3, and 3 of which were significantly down-regulated, including miR-1202 and miR-1181. [score:9]
Thirty-four miRNAs including miR-205, miR-146a, miR-200a, miR-200b, and miR-31 were significantly up-regulated, while 3 microRNAs including miR-1202 and miR-1181 were significantly down-regulated (Figure 5, Table 1). [score:7]
In agreement with the microarray results, miR-205, miR-146a, miR-200a, miR-200b, and miR-31 were up-regulated, whereas miR-1202 and miR-1181 were down-regulated in the CD133 [+] spheroid-forming subpopulation (Table 2). [score:7]
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2
[+] score: 22
lncRNA Alternative splicing [37] Neuro development [39] lincHPAT Embryo development [40] FMR4 Antiapoptotic [43] Psoriasis disease [44] 

 miRNA C19MC Preeclampsia; cancers [68] X-linked miRNA cluster Possible roles in epididymal physiology; sperm maturity; male fertility; tube development [73], [74] miR-1202 Major depressive disorder [79] miR-1908-5p Bipolar disorder [80] miR-603 Pre-miR-603 with rs11014002 SNP having protective effect toward Alzheimer’s disease [83], [84] 

 Despite the great advances, there are some limitations that need to be overcome for future studies. [score:8]
Notably, higher GRM4 protein expression is also detected in postmortem brain samples and clinical samples from patients with depression, suggesting negative correlation with the expression of miR-1202 [79]. [score:5]
These studies suggest that miR-1202 could be a potential target for new antidepressant treatment as well as biomarker for treatment prediction and response [79]. [score:3]
The primate-specific miR-1202 has recently been shown to target GRM4 [79]. [score:3]
miR-1202 is further validated experimentally to have higher expression in humans as compared to non-human primates [79]. [score:2]
In silico sequence comparison among 100 animal genomes shows that miR-1202 is present only in primates. [score:1]
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3
[+] score: 16
The other four differentially expressed miRNAs (miRNA-762, miRNA-1202, miRNA-4291 and miRNA-30a*) were not found to have the target genes anticorrelated with their expressions, indicating that they regulated the expression of target genes possibly by translational inhibition. [score:16]
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4
[+] score: 11
We observed differing expression of miR-224 and miR-383, whereas expression of the five other candidate miRNAs: miR-610, miR-637, miR-659, miR-1202 and miR-1266 did not differ significantly between ccRCC and control tissue (Figure S1, Supplemental Data). [score:5]
We identified 7 potential miRNAs targeting the 3′UTR of human DIO1 (Table 1): miR-224, miR-383, miR-610, miR-659, miR-637, miR-1202 and miR-1266. [score:3]
Expression of miR-224, miR-383, miR-610, miR-637, miR-659, miR-1202 and miR-1266 was analyzed in 32 matched pairs of tumor (T) and control (C) samples. [score:3]
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5
[+] score: 4
Nineteen of the downregulated miRNAs in chronic patients were found to be associated with carcinogenesis in various organs and tissues, such as miR-1207 [40], miR-3162-5p [41, 42], miR-3196 [43, 44], miR-371b-5p [45], miR-574-5p [46, 47], miR-1225-5p [48], miR-4485 [49], miR-572 [50], miR-4299 [51], miR-3679-5p [52], miR-3940-5p [53], miR-638 [54, 55], miR-1202 [56], miR-5787 [57], miR-1973 [58], miR-4532 [59], miR-1275 [60], miR-4728-5p [61], and miR-1915-3p [62]. [score:4]
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6
[+] score: 4
Interestingly, many of the genes containing such highly differentiated SNPs in the Alu-miRNA sites within their 3′UTRs (listed in Table 1) have target sites (encompassing these SNPs) for miRNAs that are primate-specific (miR-661 29, miR-1202 53), human-specific (miR-4739, miR-5095) 54, involved in the regulation of p53 signaling (miR-660 55, miR-661 29, miR-1285 56) or in the apoptosis pathway (miR-17 44 45, miR-30b 57, miR-106a-3p 45, miR-612 58). [score:4]
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7
[+] score: 4
Among the top ten fold changed miRNAs (Supplementary Table 1), half of them (hsa-miR-371b-5p, hsa-miR-663a, hsa-miR-1225-5p, hsa-miR-1202, and hsa-miR-572) were closely linked to the occurrence and development of tumors and might play vital roles as oncogenes or tumor suppressor genes [28– 31]. [score:4]
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8
[+] score: 3
Using a step-wise approach, we selected five exosomal miRNAs (miR-320c, miR-1202, miR-1225-5p, miR-1207-5p, and miR-7270) and validated miR-320 and miR1225-5p expression in the PLF of 18 CG patients by qRT-PCR. [score:3]
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9
[+] score: 2
In contrast, for the second set of MSCs, 6 out of the 11 miRNAs (miR-196b-5p, miR-16-5p, miR-1202, miR-572, miR-638, and miR-15b-5p) evaluated for cellular aging were statistically significant (p < 0.05) between passage 4 and 8. miRNAs, miR-572 and miR-638 were significant in the second set of MSCs and upregulated at the later passage by 1.59 and 1.35, respectively. [score:2]
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10
[+] score: 1
miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. [score:1]
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11
[+] score: 1
This little known gene resides in the short intergenic region between NOX3 and MIR1202. [score:1]
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12
[+] score: 1
miR-1202 is a primate-specific and brain-enriched microRNA involved in major depression and antidepressant treatment. [score:1]
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