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1 publications mentioning dps-mir-277

Open access articles that are associated with the species Drosophila pseudoobscura and mention the gene name mir-277. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 14
The functional enrichment of its target set suggests a much broader role for miR-277, perhaps acting as a general metabolic switch, slowing down metabolic activity by repressing translation of these genes. [score:5]
The predicted target set for worm miR-277 (the union of conserved sets for GCAUUUA, UGCAUUU) is highly enriched with fatty acid metabolism (p < 10 [−15]), carboxylic acid metabolism (p < 10 [−10]), and branched chain family amino acid metabolism (p < 10 [−8]). [score:3]
In a recent computational study, several enzymes of the branched chain amino acid degradation pathway were proposed to be targets for miR-277 [9]. [score:3]
Consistent with previous observations [17], target sites for miR-2a/2b/2c/6/13a/13b (UGUGAUA, K box) and miR-277 (AGCUUUA, Brd box) are significantly coconserved within fly 3′UTRs (p < 10 [−17]). [score:3]
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