sort by

10 publications mentioning gga-mir-130a

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-130a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 21
Several examples are: miR-17-92 which is upregulated in colonocytes coexpressing K-Ras and c-Myc, represses the expression of anti-angiogenic thrombospondin-1 (Tsp1) and connective tissue growth factor (CTGF), thus induces angiogenesis [17]; miR-378 promotes angiogenesis induced by human glioblastoma cell line U87 by targeting Fus-1 expression [18]; miR-126 regulates vascular integrity and angiogenesis, and miR-126 restoration decreases VEGF level in lung cancer cells [19], [20]; miR-130a mediates angiogenesis through downregulating antiangiogenic homeobox genes GAX and HOXA5 [21]; miR-296 level is elevated in primary brain tumor endothelial cells and regulates angiogenesis by directly targeting the hepatocyte growth factor-regulated tyrosine kinase substrate mRNA, leading to the reduction of HGS -mediated degradation of the growth factor receptors VEGFR2 and PDGFRbeta [22]. [score:21]
[1 to 20 of 1 sentences]
2
[+] score: 12
These miRNAs were divided into three groups according to their expression levels in the fat broiler line, 4 highly expressed (gga-miR-21, gga-miR-148a, gga-miR-103, gga-miR-101) (2 [-ΔCt] >0.7), 4 moderately expressed (gga-miR-100, gga-miR-146a, gga-miR-92, gga-miR-2188) (0.7>2 [-ΔCt]>0.08), and 7 lowly expressed (gga-miR-1a, gga-miR-130a, gga-miR-221, gga-miR-19a, gga-miR-181b, gga-miR-458, gga-miR-17–3p) (2 [-ΔCt]<0.08) (Table 2). [score:9]
Seven miRNAs (gga-miR-148a, gga-miR-101, gga-miR-100, gga-miR-92, gga-miR-130a, gga-miR-19a and gga-miR-221) with significantly differential expression levels were found (* P<0.05; ** P<0.01). [score:3]
[1 to 20 of 2 sentences]
3
[+] score: 10
For example, a comparison of miRNA expression profiles in proliferating myoblasts and differentiated myotubes revealed that miR-221 and miR-222 are down-regulated upon differentiation of primary and established myogenic cells, whereas miR-21, miR-103, miR-130, miR-99, miR-30 and miR20 are up-regulated [19, 33], suggesting that these miRNAs play important roles in the transition between proliferation and differentiation of muscle cells. [score:9]
In addition to miR-206, miR-1 and miR-181, nine other miRNAs among the most abundant in these libraries (miR-221, miR-222, miR-21, miR-103, miR-130, miR-99, miR-30, miR20, and miR128) have been implicated in the proliferation and differentiation of muscle cells (Table 1) [15, 19, 33]. [score:1]
[1 to 20 of 2 sentences]
4
[+] score: 4
The expression of the following miRNAs was detected: gga-let-7i, gga-mir-130a, gga-mir-130b, gga-mir-199-2, gga-mir-1639, gga-mir-1a-2, gga-mir-124a, gga-mir-219, and gga-mir-310. [score:3]
7i: gga-let-7i, 130b:gga-mir-130b, 1639: gga-mir-1639, 199-2: gga-mir-199-2, 1a-2: gga-mir-1a-2, 124a: gga-mir-124a, 130a: gga-mir-130a, 219: gga-mir-219, 301: gga-mir-301. [score:1]
[1 to 20 of 2 sentences]
5
[+] score: 4
Additional data indicate that FGF and BMP signaling pathway interactions are regulated by negative feedback loops involving microRNAs, particularly miR-130 and miR-133 [48, 49]. [score:2]
Lopez-Sanchez C. Franco D. Bonet F. Garcia-Lopez V. Aranega A. Garcia-Martinez V. Negative fgf8-bmp2 feed-back is regulated by mir-130 during early cardiac specification Dev. [score:2]
[1 to 20 of 2 sentences]
6
[+] score: 3
Some miRNAs (such as gga-miR-6516-5p and gga-miR-130a-5p) displayed less than approximately 1,000 reads, indicating that expression significantly varied among different miRNA families, which is consistent with previous studies [45]. [score:3]
[1 to 20 of 1 sentences]
7
[+] score: 2
gga-miR-221, gga-miR-222, gga-miR148, gga-miR-27b, gga-miR-34a and gga-miR-130a, which are related to differentiation and maturation, could also further influence the function of mature DCs. [score:1]
As shown in Fig. 4, gga-miR-221, gga-miR-125b, gga-miR-211, gga-miR-222a, gga-miR-193b, gga-miR-148a, gga-miR-27b, gga-miR-34a and gga-miR-130a were quantified by qRT-PCR, and these results were consistent with the sequencing analysis. [score:1]
[1 to 20 of 2 sentences]
8
[+] score: 1
In MDV infected CEFs, gga-mir-29b,-196,-133a,-10b,-30d were increased, and gga-mir-let-7a, 7b, 7f and gga-mir-1a, mir-130a were decreased [87]; of these only gga-mir-10b was increased in our data. [score:1]
[1 to 20 of 1 sentences]
9
[+] score: 1
Seven conserved families all were DE with P ≤ 0.05, including let-7 (let-7a, -7b, -7c,-7f, -7g, -7i, -7j, and -7k), miR-130 (miR-130a, and -130b), miR-146 (miR-146a, -146b, and -146c), miR-15 (miR-15a, -15b, and -15c), miR-181 (miR-181a and -181b), miR-29 (miR-29a, -29b and -29c), and miR-30 (miR-30a, -30b, -30c, -30d, and -30e). [score:1]
[1 to 20 of 1 sentences]
10
[+] score: 1
The novel miRNAs 7_32745, 17_11642, 7_32911 and 15_10888 were homologous with miR-10a-5p, miR-181a-5p, miR-26-5p and miR-130a-3p respectively (Supplementary Table 2). [score:1]
[1 to 20 of 1 sentences]