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8 publications mentioning gga-mir-99a

Open access articles that are associated with the species Gallus gallus and mention the gene name mir-99a. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 16
Of the differentially expressed miRNAs, expression of let-7b, miR-30a-5p, miR-30b, miR-99a, and miR-133b was commonly up-regulated in both dwarf and normal chickens. [score:8]
In 7-week-old chickens, as compared with 14-day-old embryos, the expression of let-7b, miR-30a-5p, miR-30b, miR-99a and miR-133b was significantly up-regulated, but miR-16c, miR-92, miR-106, miR-203, miR-451 and miR-454 were significantly down-regulated in both dwarf and normal chickens. [score:8]
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2
[+] score: 11
mir-99a and mir-99b inhibit proliferation of c-Src-transformed cells and prostate cancer cells by targeting mTOR [66, 67] and were identified as novel targets in some important biological process, such as the TGF-β -induced epithelial to mesenchymal transition [68]. [score:7]
In known miRNAs, gga-miR-26a-5p displayed greater than 12 M reads and exhibited the highest expression level followed by gga-miR-99a-5p, which displayed greater than 5 M reads. [score:3]
In pituitary and hypothalamic libraries, gga-miR-26a-5p (>12 M reads) and gga-miR-99a-5p (>5 M reads) were the most two frequently sequenced miRNAs. [score:1]
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3
[+] score: 10
For example, a comparison of miRNA expression profiles in proliferating myoblasts and differentiated myotubes revealed that miR-221 and miR-222 are down-regulated upon differentiation of primary and established myogenic cells, whereas miR-21, miR-103, miR-130, miR-99, miR-30 and miR20 are up-regulated [19, 33], suggesting that these miRNAs play important roles in the transition between proliferation and differentiation of muscle cells. [score:9]
In addition to miR-206, miR-1 and miR-181, nine other miRNAs among the most abundant in these libraries (miR-221, miR-222, miR-21, miR-103, miR-130, miR-99, miR-30, miR20, and miR128) have been implicated in the proliferation and differentiation of muscle cells (Table 1) [15, 19, 33]. [score:1]
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4
[+] score: 7
Among the five miRNAs predicted to target SREBP-1c, gga-miR-99a, gga-miR-100, gga-miR-200b and gga-miR-429 were found to be significantly (P < 0.05) up-regulated in the liver of leptin -treated chickens. [score:6]
It is noteworthy that gga-miR-99a and gga-miR-100 belong to the miRNA gene family of miR-99, while the remaining three miRNAs, gga-miR-200a, gga-miR-200b and gga-miR-429, belong to the miRNA gene family of miR-8, located in the same miRNA cluster. [score:1]
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5
[+] score: 6
The equivalent namesake mouse and zebrafish miRNAs of gga-mir-2188, gga-mir-99a-5p and gga-mir-142-3p have been shown to be involved in the development of the vascular system and hematopoiesis in the embryos of mice and zebrafish [15– 17]. [score:2]
Whilst in humans hsa-mir-99a and hsa-mir-92a are necessary for correct embryo development [20, 21]. [score:2]
Of the seven miRNAs three; gga-mir-30c-5p, gga-mir-99a-5p and gga-mir-100-5p have been reported to be present within chicken embryos [14]. [score:1]
Coppola A Romito A Borel C Gehrig C Gagnebin M Falconnet E Cardiomyogenesis is controlled by the miR-99a/let-7c cluster and epigenetic modificationsStem Cell Res. [score:1]
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6
[+] score: 6
Wang et al. identified 32 known miRNAs from skeletal muscle of Arbor Acres commercial chickens, of which 12 form five clusters: miR-133a-1-miR-1a-2, miR-23b-miR-24, miR-99a-let-7c, miR-92-miR-19b-miR-18a-miR-17, and miR-30e-miR-30c-1, suggesting that most miRNAs co-express in skeletal muscle [85]. [score:3]
3.4Wang et al. identified 32 known miRNAs from skeletal muscle of Arbor Acres commercial chickens, of which 12 form five clusters: miR-133a-1-miR-1a-2, miR-23b-miR-24, miR-99a-let-7c, miR-92-miR-19b-miR-18a-miR-17, and miR-30e-miR-30c-1, suggesting that most miRNAs co-express in skeletal muscle [85]. [score:3]
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7
[+] score: 4
In mouse and human hematopoietic stem cells, the miR-99a/100∼125b miRNAs have been implicated in the regulation of stem and intermediate progenitor cell homeostasis by controlling the balance between TGFβ and Wnt signaling (Emmrich et al., 2014). [score:2]
miR-99a/100∼125b tricistrons regulate hematopoietic stem and progenitor cell homeostasis by shifting the balance between TGFbeta and Wnt signaling. [score:2]
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8
[+] score: 2
Several miRNAs, including the miR-183 family, miR-96, miR-15, miR-99, miR-100, miR-125, and miR-133, all might contribute to hair cell development and maintenance [23– 26]. [score:2]
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