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12 publications mentioning hsa-mir-325

Open access articles that are associated with the species Homo sapiens and mention the gene name mir-325. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

[+] score: 32
We found that preterm infants with miR-325 expression had a lower probability (10%) of suffering from periventricular leukomalacia than those without miR-325 expression (50%) (P = 0.015). [score:5]
Intriguingly, a recent study examining the expression of miR-325 in the placental tissues of pregnant females reported that it was down-regulated in preeclamptic patients compared with patients with noncomplicated pregnancies (Lazar et al., 2012). [score:5]
For the 23 miRNAs with age-limited expression (Fig. 2A), miR-325 was exclusively expressed in two-thirds of preterm infants. [score:5]
For the single miRNA that was expressed in preterm infants only, miR-325, its absence of expression was associated with periventricular leukomalacia, which is a major precursor for neurological and intellectual impairment (e. g., cerebral palsy) in later life (Rezaie & Dean, 2002). [score:5]
Hence, our finding about the dysregulation of miR-325 in preterm infants, despite the limited significance level due to small sample size, provides a useful clue for the development of biomarker for periventricular leukomalacia that may lead to its prevention or treatment. [score:3]
The association was also demonstrated in the validation set of preterm infants (n = 22), with all of them showing nonexpression of miR-325 (Fig 2B) and 86.4% of them suffering from periventricular leukomalacia. [score:3]
Regarding the turning-off in the expression of miR-325 in adults, previous studies have also found that miR-325 is undetectable in the peripheral blood of adults (Liang et al., 2007). [score:3]
To explore the function of miR-325 in preterm infants, we compared the perinatal characteristics of preterm infants with miR-325 expression (n = 20) with those of preterm infants without miR-325 expression (n = 10). [score:2]
Whether this indicates that miR-325 is turned on in pregnant adults or that insufficient expression leads to pregnancy-related hypertensive disorders warrants further investigation. [score:1]
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[+] score: 21
One study that investigated the expression of miR-325 and its impact via HMGB1 targeting in HCC has shown that the expression level of miR-325 is negatively correlated with HMGB1 in HCC. [score:5]
miR-325 functions as a tumor suppressor by targeting HMGB1 and might serve as a potential prognostic marker for HCC [41]. [score:5]
Yao et al. have reported that in non-small-cell lung cancer, HMGB1 is negatively regulated by miR-325 and that an aberrant expression level of miR-325 affects cell invasion and proliferation [85]. [score:4]
Wong et al. have shown that miR-325 is upregulated in squamous cell carcinoma of the tongue [84]. [score:4]
3.4. miR-129-2. 3.5. miR-325. [score:1]
Additionally, Li et al. have shown that the negative correlation between miR-325 and tumor size, TNM stage, and metastasis in HCC highlights miR-325 as an independent prognostic factor for HCC patients [41]. [score:1]
A few studies have reported functions for miR-325 in cancer. [score:1]
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[+] score: 10
Using our mo del, we discovered human encoded miRNAs hsa-miR-489, hsa-miR-325, hsa-miR-876-3p and hsa-miR-2117 targeting HA, PB2, MP and NS of influenza A, respectively. [score:3]
hsa-miR-489, hsa-miR-325, hsa-miR-876-3p and hsa-miR-2117 are predicted to target HA, PB2, MP and NS of influenza A, respectively. [score:3]
Our mo del identified some key miRNAs including hsa-miR-489, hsa-miR-325, hsa-miR-876-3p and hsa-miR-2117, which target HA, PB2, MP and NS of H1N1, respectively. [score:3]
Because the binding energy of hsa-miR-325 and PB2 was the lowest, their binding was the most stable. [score:1]
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[+] score: 5
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-15a, hsa-mir-16-1, hsa-mir-18a, hsa-mir-19a, hsa-mir-19b-1, hsa-mir-19b-2, hsa-mir-20a, hsa-mir-21, hsa-mir-22, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-27a, hsa-mir-29a, hsa-mir-30a, hsa-mir-31, hsa-mir-33a, hsa-mir-92a-1, hsa-mir-92a-2, hsa-mir-96, hsa-mir-101-1, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-103a-2, hsa-mir-103a-1, hsa-mir-107, hsa-mir-16-2, hsa-mir-196a-1, hsa-mir-198, hsa-mir-129-1, hsa-mir-148a, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-7-1, hsa-mir-7-2, hsa-mir-7-3, hsa-mir-10a, hsa-mir-10b, hsa-mir-34a, hsa-mir-181a-2, hsa-mir-181b-1, hsa-mir-181c, hsa-mir-182, hsa-mir-183, hsa-mir-196a-2, hsa-mir-199b, hsa-mir-203a, hsa-mir-204, hsa-mir-210, hsa-mir-211, hsa-mir-212, hsa-mir-181a-1, hsa-mir-214, hsa-mir-215, hsa-mir-216a, hsa-mir-217, hsa-mir-219a-1, hsa-mir-221, hsa-mir-222, hsa-mir-223, hsa-mir-224, hsa-mir-200b, hsa-let-7g, hsa-let-7i, hsa-mir-1-2, hsa-mir-15b, hsa-mir-23b, hsa-mir-30b, hsa-mir-122, hsa-mir-124-1, hsa-mir-124-2, hsa-mir-124-3, hsa-mir-125b-1, hsa-mir-128-1, hsa-mir-130a, hsa-mir-132, hsa-mir-133a-1, hsa-mir-133a-2, hsa-mir-137, hsa-mir-138-2, hsa-mir-140, hsa-mir-141, hsa-mir-142, hsa-mir-143, hsa-mir-145, hsa-mir-9-1, hsa-mir-9-2, hsa-mir-9-3, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-127, hsa-mir-129-2, hsa-mir-138-1, hsa-mir-146a, hsa-mir-150, hsa-mir-184, hsa-mir-185, hsa-mir-195, hsa-mir-206, hsa-mir-320a, hsa-mir-200c, hsa-mir-1-1, hsa-mir-155, hsa-mir-181b-2, hsa-mir-128-2, hsa-mir-29c, hsa-mir-30c-1, hsa-mir-200a, hsa-mir-101-2, hsa-mir-219a-2, hsa-mir-34b, hsa-mir-34c, hsa-mir-301a, hsa-mir-99b, hsa-mir-296, hsa-mir-130b, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-365a, hsa-mir-365b, hsa-mir-375, hsa-mir-376a-1, hsa-mir-378a, hsa-mir-382, hsa-mir-383, hsa-mir-151a, hsa-mir-148b, hsa-mir-338, hsa-mir-133b, hsa-mir-196b, hsa-mir-424, hsa-mir-20b, hsa-mir-429, hsa-mir-451a, hsa-mir-409, hsa-mir-412, hsa-mir-376b, hsa-mir-483, hsa-mir-146b, hsa-mir-202, hsa-mir-181d, hsa-mir-499a, hsa-mir-376a-2, hsa-mir-92b, hsa-mir-33b, hsa-mir-151b, hsa-mir-320b-1, hsa-mir-320c-1, hsa-mir-320b-2, hsa-mir-378d-2, hsa-mir-301b, hsa-mir-216b, hsa-mir-103b-1, hsa-mir-103b-2, hsa-mir-320d-1, hsa-mir-320c-2, hsa-mir-320d-2, hsa-mir-378b, hsa-mir-320e, hsa-mir-378c, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-219b, hsa-mir-203b, hsa-mir-451b, hsa-mir-499b, hsa-mir-378j
Another corticotrophin-releasing factor, urocortin 2, promotes expression of miR-325-3p in pituitary and suppresses biosynthesis and secretion of luteinizing hormone in rat (Nemoto et al. 2012). [score:5]
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[+] score: 5
Nemoto T Mano A Shibasaki T Increased expression of miR-325-3p by urocortin 2 and its involvement in stress -induced suppression of LH secretion in rat pituitaryAmerican journal of physiology. [score:5]
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[+] score: 3
A study comparing miRNA expression in human subcutaneous and omental (visceral) adipose tissue found negative correlations between miR-99a, miR-325 and IL-6 concentration [88]. [score:3]
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[+] score: 2
Pre-clinical studies in healthy mice and in vitro studies using estrogen have identified miRNAs either regulated by estrogen (miR-203, miR-126, miR-23a, miR-21, miR-24, miR-27a and b, and miR-106a and b) or encoded by X-chromosome (miR-98, miR-652, miR-221, miR-222, miR-223, miR-361, miR-421, miR-325, miR-188, miR-92a, miR-424, miR-503, miR-505). [score:2]
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[+] score: 1
The other two members, were hybridized to the probes for mouse miR-106a and mouse miR-325. [score:1]
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[+] score: 1
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-mir-16-1, hsa-mir-17, hsa-mir-18a, hsa-mir-19b-1, hsa-mir-19b-2, hsa-mir-20a, hsa-mir-21, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-29a, hsa-mir-31, hsa-mir-99a, hsa-mir-100, hsa-mir-29b-1, hsa-mir-29b-2, hsa-mir-106a, hsa-mir-16-2, hsa-mir-192, hsa-mir-199a-1, hsa-mir-208a, hsa-mir-30c-2, hsa-mir-147a, hsa-mir-10a, hsa-mir-34a, hsa-mir-181b-1, hsa-mir-199a-2, hsa-mir-203a, hsa-mir-204, hsa-mir-217, hsa-mir-219a-1, hsa-mir-221, hsa-mir-222, hsa-mir-223, hsa-mir-200b, hsa-mir-27b, hsa-mir-30b, hsa-mir-122, hsa-mir-125b-1, hsa-mir-132, hsa-mir-140, hsa-mir-142, hsa-mir-143, hsa-mir-145, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-146a, hsa-mir-150, hsa-mir-185, hsa-mir-193a, hsa-mir-195, hsa-mir-200c, hsa-mir-155, hsa-mir-181b-2, hsa-mir-30c-1, hsa-mir-219a-2, hsa-mir-296, hsa-mir-130b, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-302d, hsa-mir-374a, hsa-mir-375, hsa-mir-378a, hsa-mir-330, hsa-mir-328, hsa-mir-342, hsa-mir-424, hsa-mir-429, hsa-mir-450a-1, hsa-mir-486-1, hsa-mir-146b, hsa-mir-497, hsa-mir-520e, hsa-mir-520f, hsa-mir-520a, hsa-mir-520b, hsa-mir-520c, hsa-mir-520d, hsa-mir-520g, hsa-mir-520h, hsa-mir-450a-2, hsa-mir-503, hsa-mir-608, hsa-mir-625, hsa-mir-629, hsa-mir-663a, hsa-mir-1271, hsa-mir-769, hsa-mir-378d-2, hsa-mir-675, hsa-mir-147b, hsa-mir-374b, hsa-mir-663b, hsa-mir-378b, hsa-mir-378c, hsa-mir-374c, hsa-mir-378d-1, hsa-mir-378e, hsa-mir-378f, hsa-mir-378g, hsa-mir-378h, hsa-mir-378i, hsa-mir-4661, hsa-mir-219b, hsa-mir-203b, hsa-mir-378j, hsa-mir-486-2
In contrast, miR-325 and miR-99a obtained from the subcutaneous and omental white adipose tissue of Caucasian individuals present a negative correlation with the secretion of IL-6 [53]. [score:1]
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[+] score: 1
miR-761 and miR-325 were induced and repressed by LO diet, respectively. [score:1]
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[+] score: 1
miRNA Normalized Mean Values ± SD [Sample 1–Sample 2] miRNA Normalized Mean Values ± SD [Sample 1–Sample 2] let-7b-3p 4.73 ± 2.21 [6.30–3.17] miR-320b 8.93 ± 0.22 [9.08–8.77] let-7e-5p 5.24 ± 0.032 [5.22–5.27] miR-325 5.15 ± 0.72 [4.64–5.66] let-7f-5p 5.24 ± 1.49 [4.18–6.29] miR-330-3p 9.23 ± 2.37 [7.56–10.91] let-7f-2-3p 7.90 ± 0.10 [7.83–7.97] miR-337-3p 2.70 ± 1.19 [1.86–3. [score:1]
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[+] score: 1
Other miRNAs from this paper: hsa-mir-4428
From the 1433 ncRNAs having a P-value smaller than 10 [–5], a threshold that corresponds to the previously reported sequence similarity between the mir-325 family and the L2 repeats, 68 87% (1248) were related to miRNAs. [score:1]
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