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15 publications mentioning rno-mir-342

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-342. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 24
Additionally, downregulated miR-342-3p expression is part of a shared dysregulated miRNA expression profile in both mutated non-invasive follicular thyroid neoplasms with papillary-like nuclear features (NIFTPs) and infiltrative and invasive follicular variants of papillary thyroid carcinomas (FVPTCs); and in contrast to wild type NIFTPs, this dysregulated miRNA expression profile is predicted to promote an invasive-like phenotype by altering cell adhesion and cell migration pathways [62]. [score:12]
The microarray results demonstrated significantly decreased expression of 54 miRNAs in the renal cortices from the Cd -treated group versus the saline control group, and miR-193b-3p, miR-455-3p, and miR-342-3p demonstrated a more abundant expression level and a two-fold or greater decreased expression in the Cd-treatment group versus the saline control group. [score:7]
miR-193b-3p, miR-455-3p, and miR-342-3p demonstrated more abundant expression and a two-fold or greater significant decreased expression with Cd treatment. [score:5]
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2
[+] score: 24
Eleven of the altered miRNAs were downregulated (miR-122, miR-93*, miR-872, miR-7*, miR-146a, miR-342-3p, miR-150, miR-139, miR-30a, miR-30e, miR-320), whereas three miRNAs, namely miR-463*, miR-34c* and miR-1188, were upregulated in the RYGB group. [score:7]
Downregulated plasma miR-342-3p and upregulated miR-34c* in RYGB-operated rats demonstrate a broad correlation with the liver, plasma and urinary metabolite profiles, indicating their extensive involvement in metabolic processes. [score:7]
In particular, miR-342-3p, miR-320, miR-139-5p and miR-146a were predicted to be involved in multiple neurological transmitter and receptor-related pathways, as well as two major neurodegenerative disease -associated pathways (Parkinson's and Huntingtons diseases), suggesting that RYGB surgery may modulate neurological activity through a miRNA -mediated gut-brain axis. [score:5]
Decreased plasma levels of miR-342-3p, miR-320, miR-139-5p and miR-146a observed in our study suggest RYGB surgery impact on multiple neurodegenerative disease-related pathways. [score:3]
In addition to miR-342-3p and miR-34c*, miR-872*, miR-463*, miR-30e, miR-2183, miR-1971, miR-150, miR-146a, miR-1188 and miR-93* all correlate with liver energy metabolism processes, such as glycolysis and glycogenesis involving glucose, glycogen and lactate. [score:1]
Furthermore, miR-206, miR-1188, miR-1971 and miR-34c* are inversely correlated with plasma lipid fractions, whereas miR-320 and miR-342-3p and to a lesser extent miR-7*, exhibit a positive correlation. [score:1]
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3
[+] score: 20
The expression of miR-320, miR-129* and miR-342-3p was significantly down-regulated by RDX. [score:6]
MiRNAs Target Genes Names Regulation Up Down miR-135a Up KIAA1033, CEP350, ROCK2 miR-320 Down BANP, CALD1, POLE4 miR-98 Up SULF1 miR-129* Down BANP, FAM82A2 miR-27ab Up HMGCR, LITAF, NPTX2 CALD1, C5orf13, KIAA1033 miR-342-3P Down VGF KIAA1033 miR-7a Up SLC38A2 POLE4, SLC35E4, C5orf13 miR-674-5p Up VGFBiological functional analysis revealed that more than half (8) of the overlapped genes are involved in neurological diseases and nervous system function (Table 4). [score:6]
MiRNAs Target Genes Names Regulation Up Down miR-135a Up KIAA1033, CEP350, ROCK2 miR-320 Down BANP, CALD1, POLE4 miR-98 Up SULF1 miR-129* Down BANP, FAM82A2 miR-27ab Up HMGCR, LITAF, NPTX2 CALD1, C5orf13, KIAA1033 miR-342-3P Down VGF KIAA1033 miR-7a Up SLC38A2 POLE4, SLC35E4, C5orf13 miR-674-5p Up VGF Biological functional analysis revealed that more than half (8) of the overlapped genes are involved in neurological diseases and nervous system function (Table 4). [score:6]
MiR-342-3p has been found to play a role in neurodegenration [12] and prion disease [30]. [score:2]
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4
[+] score: 17
The miRNA array data have been deposited in the Gene Expression Omnibus (accession number [GEO: GSE22181]) miRNA expression was quantified using real-time RT-PCR on the Applied Biosystems 7500 Real-Time PCR System (Applied Biosystems) to verify the upregulated miRNA targets detected by the miRNA array from the spinal segments (miR-384-3p, miR-325-5p, miR-342-5p, and miR-340-5p) and DRGs (miR-21) in the denervation and sham control groups, and the muscle-specific miRNAs (miR-1, miR-133a, and miR-206) in the soleus muscles of the sham control, entrapment, and decompression groups. [score:10]
In the denervation group, 4 miRNAs (miR-384-3p, miR-325-5p, miR-342-5p, and miR-340-5p) were significantly upregulated, but no miRNA was downregulated in the spinal segment specimens after 6 months. [score:7]
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5
[+] score: 6
Then to choose miRNAs (miR-133b, miR-342 and miR-30a) relevant to DKD and acting as epigenetic regulators of the former autophagy genes based on previous microarray studies; (2) Experimental validation to characterize the efficacy of caffeic acid on modulating the expression of chosen miRNA-autophagy target gene pairs in HFD-STZ induced rat mo del. [score:4]
Moreover, miR-342-5p is coupled to the antiviral IFN response [39] which in turn linked to autophagy. [score:1]
Correlations miRNA-133b miRNA-342 miRNA-30a ATG12 MAPLC3 RB1CC1 miRNA-133b Correlation Coefficient 1.0000.893 [**] 0.546 [**] −0.483 [**] −0.425 [**] −0.543 [**] Sig. [score:1]
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6
[+] score: 6
Among the important genes were Lifr, Acvr1c, and Pparγ which were found to be targeted by microRNAs in our dataset like miR-143, miR-30, miR-140, miR-27b, miR-125a, miR-128ab, miR-342, miR-26ab, miR-181, miR-150, miR-23ab and miR-425. [score:3]
It was found to be targeted by multiple microRNAs in our analysis, including miR-143, miR-30 family members, miR-140, miR-27b, miR-125a-5p, miR-128ab, and miR-342-3p. [score:3]
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7
[+] score: 6
miRNAs such as miR-133a, miR-185, miR-152, miR-34a and miR-342 which were reported to show increased expression were also up-regulated in our rat mo del. [score:6]
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8
[+] score: 5
Similarly, several downregulated microRNAs were associated with genes participating in cell death process, such as yy1 (miR-294) [34], the pro-apoptotic factor bim (miR-144), the pro-apoptotic blcap (miR-294), which stimulates apoptosis independently of p53 and NF-κB [35], and the anti-apoptotic factor Bcl-XL (miR-342) (Figure 7, networks 1, 3 and 4). [score:4]
Specifically, BDNF is related to miR-183, semaphorin 3 to miR-329 and miR-331, Neuritin-1/ nrn1 to miR-331 and miR-342 and Ephrin-B2/ efnb2 to miR-340 and miR-294. [score:1]
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9
[+] score: 5
Other miRNAs from this paper: mmu-mir-30a, mmu-mir-101a, mmu-mir-125a, mmu-mir-125b-2, mmu-mir-132, mmu-mir-134, mmu-mir-135a-1, mmu-mir-138-2, mmu-mir-142a, mmu-mir-150, mmu-mir-154, mmu-mir-182, mmu-mir-183, mmu-mir-24-1, mmu-mir-194-1, mmu-mir-200b, mmu-mir-122, mmu-mir-296, mmu-mir-21a, mmu-mir-27a, mmu-mir-92a-2, mmu-mir-96, rno-mir-322-1, mmu-mir-322, rno-mir-330, mmu-mir-330, rno-mir-339, mmu-mir-339, mmu-mir-342, rno-mir-135b, mmu-mir-135b, mmu-mir-19a, mmu-mir-100, mmu-mir-139, mmu-mir-212, mmu-mir-181a-1, mmu-mir-214, mmu-mir-224, mmu-mir-135a-2, mmu-mir-92a-1, mmu-mir-138-1, mmu-mir-181b-1, mmu-mir-125b-1, mmu-mir-194-2, mmu-mir-377, mmu-mir-383, mmu-mir-181b-2, rno-mir-19a, rno-mir-21, rno-mir-24-1, rno-mir-27a, rno-mir-30a, rno-mir-92a-1, rno-mir-92a-2, rno-mir-96, rno-mir-100, rno-mir-101a, rno-mir-122, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-132, rno-mir-134, rno-mir-135a, rno-mir-138-2, rno-mir-138-1, rno-mir-139, rno-mir-142, rno-mir-150, rno-mir-154, rno-mir-181b-1, rno-mir-181b-2, rno-mir-183, rno-mir-194-1, rno-mir-194-2, rno-mir-200b, rno-mir-212, rno-mir-181a-1, rno-mir-214, rno-mir-296, mmu-mir-376b, mmu-mir-370, mmu-mir-433, rno-mir-433, mmu-mir-466a, rno-mir-383, rno-mir-224, mmu-mir-483, rno-mir-483, rno-mir-370, rno-mir-377, mmu-mir-542, rno-mir-542-1, mmu-mir-494, mmu-mir-20b, mmu-mir-503, rno-mir-494, rno-mir-376b, rno-mir-20b, rno-mir-503-1, mmu-mir-1224, mmu-mir-551b, mmu-mir-672, mmu-mir-455, mmu-mir-490, mmu-mir-466b-1, mmu-mir-466b-2, mmu-mir-466b-3, mmu-mir-466c-1, mmu-mir-466e, mmu-mir-466f-1, mmu-mir-466f-2, mmu-mir-466f-3, mmu-mir-466g, mmu-mir-466h, mmu-mir-504, mmu-mir-466d, mmu-mir-872, mmu-mir-877, rno-mir-466b-1, rno-mir-466b-2, rno-mir-466c, rno-mir-872, rno-mir-877, rno-mir-182, rno-mir-455, rno-mir-672, mmu-mir-466l, mmu-mir-466i, mmu-mir-466f-4, mmu-mir-466k, mmu-mir-466j, rno-mir-551b, rno-mir-490, rno-mir-1224, rno-mir-504, mmu-mir-466m, mmu-mir-466o, mmu-mir-466c-2, mmu-mir-466b-4, mmu-mir-466b-5, mmu-mir-466b-6, mmu-mir-466b-7, mmu-mir-466p, mmu-mir-466n, mmu-mir-466b-8, rno-mir-466d, mmu-mir-466q, mmu-mir-21b, mmu-mir-21c, mmu-mir-142b, mmu-mir-466c-3, rno-mir-322-2, rno-mir-503-2, rno-mir-466b-3, rno-mir-466b-4, rno-mir-542-2, rno-mir-542-3
NR5A1 was predicted to be the target gene of miR-342, while LDL-R was predicted to be the target gene of miR-182 and miR-466b. [score:5]
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10
[+] score: 5
Serum was collected from different stage at 1 [st] to 6 [th] week and the expression levels of 4 top ranked miRNAs (miR-25-3p, miR-140-5p, miR-342-5p and miR-150-5p) were assayed by qPCR. [score:2]
By geNorm, miR-25-3p was ranked as the most stable gene and a combination of miR-25-3p, miR-342-5p and miR-140-5p was recommended for optimal normalization (Fig. 2a). [score:1]
Therefore, ten miRNAs (miR-19b-3p, miR-21-5p, miR-25-3p, miR-30a-5p, miR-133b-3p, miR-140-5p, miR-150-5p, miR-199a-3p, miR-342-5p, miR-3473) were chosen as candidate reference genes. [score:1]
Conversely, miR-140-5p, miR-342-5p and miR-150-5p were not as stable as miR-25-3p and showed some notable changes at some stage (Fig. 2c). [score:1]
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11
[+] score: 3
The luciferase values were further normalized to the average luciferase value obtained after transfecting a panel of microRNAs not predicted to target the rat Arc 3′UTR (rno-miR-370, rno-miR-150, rno-miR-342, rno-miR-30b, rno-miR-105, rno-miR-145 and rno-miR-9). [score:3]
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12
[+] score: 1
Consonant with the role of microRNA, there have been some early reports that the majority of colorectal cancer patients had epigenetic silencing of the intronic micro RNA miR-342 in the uninvolved mucosa (with >80% of tumor tissue manifesting concomitant loss) [19]. [score:1]
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13
[+] score: 1
Among the 21 miRNAs altered at 24 hours, 5 (miR-144, miR-136, miR-148b-5p, miR-342-5p, miR-23a*) showed persistent changes by 7 days after CCI (Figure 1C, D). [score:1]
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14
[+] score: 1
For example, seven microRNAs, including miR-1, miR-200c, miR-340, miR-342, miR-325, miR-139 and miR-500 contributed to the association with heart failure (P-value = 2.74e-3). [score:1]
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15
[+] score: 1
Other miRNAs from this paper: hsa-let-7a-1, hsa-let-7a-2, hsa-let-7a-3, hsa-let-7b, hsa-let-7c, hsa-let-7d, hsa-let-7e, hsa-let-7f-1, hsa-let-7f-2, hsa-mir-16-1, hsa-mir-17, hsa-mir-21, hsa-mir-23a, hsa-mir-24-1, hsa-mir-24-2, hsa-mir-25, hsa-mir-26a-1, hsa-mir-26b, hsa-mir-30a, hsa-mir-31, hsa-mir-96, hsa-mir-99a, hsa-mir-16-2, hsa-mir-30c-2, hsa-mir-30d, hsa-mir-182, hsa-mir-183, hsa-mir-211, hsa-mir-217, hsa-mir-218-1, hsa-mir-218-2, hsa-mir-221, hsa-mir-222, hsa-let-7g, hsa-let-7i, hsa-mir-15b, hsa-mir-23b, hsa-mir-30b, hsa-mir-125b-1, hsa-mir-132, hsa-mir-143, hsa-mir-145, hsa-mir-191, hsa-mir-125a, hsa-mir-125b-2, hsa-mir-126, hsa-mir-184, hsa-mir-190a, hsa-mir-195, rno-mir-322-1, rno-let-7d, rno-mir-335, rno-mir-135b, hsa-mir-30c-1, hsa-mir-299, hsa-mir-30e, hsa-mir-26a-2, hsa-mir-379, hsa-mir-382, hsa-mir-342, hsa-mir-135b, hsa-mir-335, rno-let-7a-1, rno-let-7a-2, rno-let-7b, rno-let-7c-1, rno-let-7c-2, rno-let-7e, rno-let-7f-1, rno-let-7f-2, rno-let-7i, rno-mir-15b, rno-mir-16, rno-mir-17-1, rno-mir-21, rno-mir-23a, rno-mir-23b, rno-mir-24-1, rno-mir-24-2, rno-mir-25, rno-mir-26a, rno-mir-26b, rno-mir-30c-1, rno-mir-30e, rno-mir-30b, rno-mir-30d, rno-mir-30a, rno-mir-30c-2, rno-mir-31a, rno-mir-96, rno-mir-99a, rno-mir-125a, rno-mir-125b-1, rno-mir-125b-2, rno-mir-126a, rno-mir-132, rno-mir-143, rno-mir-145, rno-mir-183, rno-mir-184, rno-mir-190a-1, rno-mir-191a, rno-mir-195, rno-mir-211, rno-mir-217, rno-mir-218a-2, rno-mir-218a-1, rno-mir-221, rno-mir-222, rno-mir-299a, hsa-mir-384, hsa-mir-20b, hsa-mir-409, hsa-mir-412, hsa-mir-489, hsa-mir-494, rno-mir-489, rno-mir-412, rno-mir-543, rno-mir-542-1, rno-mir-379, rno-mir-494, rno-mir-382, rno-mir-409a, rno-mir-20b, hsa-mir-542, hsa-mir-770, hsa-mir-190b, hsa-mir-543, rno-mir-466c, rno-mir-17-2, rno-mir-182, rno-mir-190b, rno-mir-384, rno-mir-673, rno-mir-674, rno-mir-770, rno-mir-31b, rno-mir-191b, rno-mir-299b, rno-mir-218b, rno-mir-126b, rno-mir-409b, rno-let-7g, rno-mir-190a-2, rno-mir-322-2, rno-mir-542-2, rno-mir-542-3
Similarly, stepwise artificial neural networks analysis revealed predictive miRNA signatures (miR-342, miR-299, miR-217, miR-190, miR-135b, miR-218) corresponding to oestrogen receptor status in breast cancer [39]. [score:1]
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