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11 publications mentioning rno-mir-325

Open access articles that are associated with the species Rattus norvegicus and mention the gene name mir-325. Click the [+] symbols to view sentences that include the gene name, or the word cloud on the right for a summary.

1
[+] score: 17
The miRNA array data have been deposited in the Gene Expression Omnibus (accession number [GEO: GSE22181]) miRNA expression was quantified using real-time RT-PCR on the Applied Biosystems 7500 Real-Time PCR System (Applied Biosystems) to verify the upregulated miRNA targets detected by the miRNA array from the spinal segments (miR-384-3p, miR-325-5p, miR-342-5p, and miR-340-5p) and DRGs (miR-21) in the denervation and sham control groups, and the muscle-specific miRNAs (miR-1, miR-133a, and miR-206) in the soleus muscles of the sham control, entrapment, and decompression groups. [score:10]
In the denervation group, 4 miRNAs (miR-384-3p, miR-325-5p, miR-342-5p, and miR-340-5p) were significantly upregulated, but no miRNA was downregulated in the spinal segment specimens after 6 months. [score:7]
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2
[+] score: 12
We found that miR-142, miR-200c, miR-212, miR-325, miR-361, miR-376c, miR-429, and miR-494 overexpression could down-regulate the CRH mRNA level (p < 0.05; Figure 6A), and there was no difference between these miRNAs and the negative miRNA control (p > 0.05) in terms of cell viability (Supplementary Figure S2A). [score:6]
CRH protein expression (A) in primary hypothalamus neurons transfected with miR-142, miR-200c, miR-325, miR-361, miR-376c and miR-429 agomir or the negative control. [score:3]
Besides, miR-142, miR-200c, miR-325, miR-361, miR-376c and miR-429 overexpression could decrease the level of CRHR1 mRNA simultaneously (p < 0.05; Figure 6B). [score:3]
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3
[+] score: 7
Among the miRNAs, miR-214, miR-199a-5p, miR-150, miR-199a-3p, miR-351, miR-145, miR-764, miR-497 and miR-92b were upregulated, whilst miR-7a, miR-325-5p, miR-485, miR-708, miR-344-3p, let-7f, miR-26b, miR-129, miR-29c and let-7a were downregulated. [score:7]
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4
[+] score: 6
0145116.g006 Fig 6Relative miRNA expression levels of miR-200c-3p (A), miR-141-3p (B), miR-325-3p (C), miR-2137 (D), miR-210-3p (E), miR-181a-5p (F), miR-204-5p (G), miR-455-3p (H), miR-137-3p (I), miR-135a-5p (J), miR-384-5p (K) in rat exocrine fractions, rat islets, AR42J cells, B13 cells and B13 transduced with Ad-GFP or Ad-PNM at 4 days post-transduction, quantified by individual qPCR assays. [score:2]
Relative miRNA expression levels of miR-200c-3p (A), miR-141-3p (B), miR-325-3p (C), miR-2137 (D), miR-210-3p (E), miR-181a-5p (F), miR-204-5p (G), miR-455-3p (H), miR-137-3p (I), miR-135a-5p (J), miR-384-5p (K) in rat exocrine fractions, rat islets, AR42J cells, B13 cells and B13 transduced with Ad-GFP or Ad-PNM at 4 days post-transduction, quantified by individual qPCR assays. [score:2]
The differential expression of miR-200c-3p, miR-141-3p and miR-325-3p between AR42J and non-transduced B13 cells (Table 1) was further confirmed by the individual qPCR assays (Fig 6A–6C). [score:2]
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5
[+] score: 6
According to the present study, several miRNAs were observed to target cholesterol metabolism -associated DEGs, including miR210, miR300-3p, miR-325-5p, miR-487b and miR-16. [score:3]
In addition, a number of miRNAs, including miR-16, miR-210, miR-15b, miR300-3p, miR-540, miR-325-5p and miR-487b, were observed to have target DEGs involved in cholesterol -associated metabolism, e. g. IDI1 and FDFT1. [score:3]
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6
[+] score: 6
For example, miR-325-3p is associated with the immobilization -induced suppression of LH secretion [11], and miR-375 is involved in ATCH secretion [27]. [score:3]
Hasuwa et al. indicated that miR-200b/miR-429 stimulates luteinizing hormone (LH) levels by targeting ZEB1 [10], and Nemoto et al. showed that miR-325-3p decreases LH secretion [11]. [score:3]
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7
[+] score: 5
Nemoto T Mano A Shibasaki T Increased expression of miR-325-3p by urocortin 2 and its involvement in stress -induced suppression of LH secretion in rat pituitaryAmerican journal of physiology. [score:5]
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8
[+] score: 3
Compared to the other 2 groups, 21 miRNAs are upregulated in 6-hour group as shown in the upper portion of Fig. 2, miR-9, miR-204, miR-335, miR-23a, miR-708, miR-146a, miR-325-5p, miR-106b, miR-143, miR-140, miR-376b-3p, miR-7a, miR-541, miR-185, miR-499, miR-127*, miR-320, miR-140*, miR-145*, miR-423*, miR-378. [score:3]
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9
[+] score: 2
The results for the other two miRs (miR-130a and miR-325) observed in the microarray were not confirmed with qPCR. [score:1]
Ct values were <30.60 for miR-133b, <27.78 for miR-145, <27.66 for miR-193b, <30.19 for miR-143, <33.69 for miR-335, <23.42 for miR-191, <37.89 for miR-130a, <36.00 for miR-325, <32.04 for miR-1. Reference miRs were: MammU6-4395470 (Ct values < 19.30), snoRNA135-4380912 (Ct values < 33.98), and U87-4386735 (Ct values < 28.32). [score:1]
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10
[+] score: 1
miR-761 and miR-325 were induced and repressed by LO diet, respectively. [score:1]
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11
[+] score: 1
For example, seven microRNAs, including miR-1, miR-200c, miR-340, miR-342, miR-325, miR-139 and miR-500 contributed to the association with heart failure (P-value = 2.74e-3). [score:1]
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