Stem-loop sequence rno-mir-181b-2

Accession

MI0000927 (change log)

Description

Rattus norvegicus miR-181b-2 stem-loop

Gene family

MIPF0000007; mir-181

Literature search

32 open access papers mention rno-mir-181b-2
(184 sentences)

Stem-loop

   -uga     -   cucaa         cug          ---  a 
5'     uggcu gca     cauucauug   ucgguggguu   ug a
       ||||| |||     |||||||||   ||||||||||   || u
3'     accgg cgu     guaaguaac   ggucacucaa   ac g
   aaaa     g   caaac         --u          cca  u 

Deep sequencing

2832307 reads, 1.89e+03 reads per million, 508 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (Rnor_6.0; GCA_000001895.4): chr3: 23151455-23151542 [+]
• Overlapping transcripts:

  antisense

  ENSRNOT00000072113 ; Nr6a1-203; intron 1

  ENSRNOT00000074794 ; Nr6a1-202; intron 2

Clustered miRNAs

< 10kb from rno-mir-181b-2

• rno-mir-181a-2: chr3: 23150352-23150468 [+]
• rno-mir-181b-2: chr3: 23151455-23151542 [+]

Database links

• EntrezGene:Mir181b-2
• miRBase Tracker:MI0000927

Mature sequence rno-miR-181b-5p

• Accession: MIMAT0000859
• Previous IDs: rno-miR-181b
• Sequence: 15 - aacauucauugcugucggugggu - 37
• Deep sequencing: 5655273 reads, 510 experiments
• Evidence: experimental; cloned [1-2], SOLiD [3]
• Predicted targets:
  • TargetScanVert:rno-miR-181b-5p
  • miRDB:rno-miR-181b-5p
  • microrna.org:rno-miR-181b-5p

Mature sequence rno-miR-181b-2-3p

• Accession: MIMAT0017140
• Previous IDs: rno-miR-181b-2*
• Sequence: 53 - cucacuggucaaugaaugcaaa - 74
• Deep sequencing: 1676 reads, 322 experiments
• Evidence: experimental; SOLiD [3]
• Predicted targets:
  • TargetScanVert:rno-miR-181b-2-3p
  • miRDB:rno-miR-181b-2-3p

References

1. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
2. PMID:17805466 "Cloning and identification of novel microRNAs from rat hippocampus" He X, Zhang Q, Liu Y, Pan X Acta Biochim Biophys Sin (Shanghai). 39:708-714(2007).
3. PMID:20403161 "Small RNA expression and strain specificity in the rat" Linsen SE, de Wit E, de Bruijn E, Cuppen E BMC Genomics. 11:249(2010).