Stem-loop sequence mmu-mir-344-1

Accession

MI0000630 (change log)

Previous IDs

mmu-mir-344

Symbol

MGI:Mir344

Description

Mus musculus miR-344-1 stem-loop

Gene family

MIPF0000267; mir-344

Literature search

10 open access papers mention mmu-mir-344-1
(33 sentences)

Stem-loop

   cugcagc        uuac          cc         uc        a 
5'        caggguuu    cagucaggcu  uggcuagau  cagguacc g
          ||||||||    ||||||||||  |||||||||  ||||||||  
3'        gucccgaa    gucaguccga  accgaucua  guccaugg c
   ---acaa        ---u          -a         --        u 

Deep sequencing

20851 reads, 87 reads per million, 54 experiments

Confidence

Annotation confidence: not enough data

Feedback: Do you believe this miRNA is real?

Comments

Kim et al. cloned 40 new miRNAs from rat E18 primary cortical neurons [1]. This mouse miRNA is predicted based on homology to the verified rat sequence (MI0000629) - its expression was later independently verified in mouse [2].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr7: 61877770-61877864 [-]
• Overlapping transcripts:

  intergenic

Database links

• EntrezGene:Mirn344
• MGI:Mir344
• RNAcentral:URS000071EB77_10090
• miRBase Tracker:MI0000630

Mature sequence mmu-miR-344-5p

• Accession: MIMAT0017038
• Previous IDs: mmu-miR-344*
• Sequence: 21 - agucaggcuccuggcuagauuccagg - 46
• Deep sequencing: 112 reads, 14 experiments
• Evidence: experimental; Illumina [3]
• Database links:
  • RNAcentral:URS000012FB60_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-344-5p
  • miRDB:mmu-miR-344-5p

Mature sequence mmu-miR-344-3p

• Accession: MIMAT0000593
• Previous IDs: mmu-miR-344
• Sequence: 61 - ugaucuagccaaagccugacugu - 83
• Deep sequencing: 41588 reads, 54 experiments
• Evidence: experimental; cloned [1], Illumina [2-3]
• Database links:
  • RNAcentral:URS0000504AEF_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-344-3p
  • miRDB:mmu-miR-344-3p
  • microrna.org:mmu-miR-344-3p

References

1. PMID:14691248 "Identification of many microRNAs that copurify with polyribosomes in mammalian neurons" Kim J, Krichevsky A, Grad Y, Hayes GD, Kosik KS, Church GM, Ruvkun G Proc Natl Acad Sci U S A. 101:360-365(2004).
2. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).