Stem-loop sequence mmu-mir-466d

Accession

MI0005546 (change log)

Symbol

MGI:Mir466d

Description

Mus musculus miR-466d stem-loop

Gene family

MIPF0000316; mir-467

Literature search

30 open access papers mention mmu-mir-466d
(89 sentences)

Stem-loop

   --ca       u            - -    --a a            aa 
5'     ugugugu ugugugugcgua c augu   c uguguguauaug  u
       ||||||| |||||||||||| | ||||   | ||||||||||||   
3'     acacaca acacgcacgcau g uaca   g acauacauauac  a
   ggac       c            a a    cac c            au 

Deep sequencing

24976 reads, 2.67e+03 reads per million, 159 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

miR-466d-3p reported in [1] has an additional 3' U base which is inconsistent with the current genome sequence (as shown here).

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr2: 10511967-10512062 [+]
• Overlapping transcripts:

  sense

  OTTMUST00000026263 ; Sfmbt2-001; intron 10

  ENSMUST00000041105 ; Sfmbt2-001; intron 10

  ENSMUST00000116594 ; Sfmbt2-201; intron 11

Clustered miRNAs

< 10kb from mmu-mir-466d

• mmu-mir-467a-10: chr2: 10503273-10503355 [+]
• mmu-mir-466b-3: chr2: 10503565-10503645 [+]
• mmu-mir-669a-12: chr2: 10503791-10503877 [+]
• mmu-mir-467e: chr2: 10505721-10505807 [+]
• mmu-mir-466p: chr2: 10506006-10506094 [+]
• mmu-mir-467d: chr2: 10507630-10507714 [+]
• mmu-mir-466a: chr2: 10507918-10507990 [+]
• mmu-mir-297c: chr2: 10509016-10509113 [+]
• mmu-mir-669c: chr2: 10509296-10509404 [+]
• mmu-mir-669a-2: chr2: 10510164-10510260 [+]
• mmu-mir-297b: chr2: 10511667-10511775 [+]
• mmu-mir-466d: chr2: 10511967-10512062 [+]
• mmu-mir-669m-1: chr2: 10512790-10512887 [+]
• mmu-mir-669m-2: chr2: 10513434-10513531 [+]
• mmu-mir-466n: chr2: 10513741-10513834 [+]
• mmu-mir-669o: chr2: 10514300-10514395 [+]
• mmu-mir-466g: chr2: 10514595-10514674 [+]
• mmu-mir-466h: chr2: 10514891-10514971 [+]
• mmu-mir-297a-3: chr2: 10515820-10515921 [+]
• mmu-mir-466l: chr2: 10516097-10516217 [+]
• mmu-mir-297a-4: chr2: 10517067-10517164 [+]
• mmu-mir-669i: chr2: 10517604-10517730 [+]
• mmu-mir-669h: chr2: 10518155-10518279 [+]

Database links

• EntrezGene:Mir466d
• MGI:Mir466d
• RNAcentral:URS000075CEBD_10090
• miRBase Tracker:MI0005546

Mature sequence mmu-miR-466d-5p

• Accession: MIMAT0004930
• Sequence: 11 - ugugugugcguacauguacaug - 32
• Deep sequencing: 1802 reads, 81 experiments
• Evidence: experimental; cloned [1], Illumina [3-4]
• Database links:
  • RNAcentral:URS000023A254_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-466d-5p
  • miRDB:mmu-miR-466d-5p
  • microrna.org:mmu-miR-466d-5p

Mature sequence mmu-miR-466d-3p

• Accession: MIMAT0004931
• Sequence: 51 - uauacauacacgcacacauag - 71
• Deep sequencing: 20673 reads, 101 experiments
• Evidence: experimental; cloned [1], 454 [2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00005E6C56_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-466d-3p
  • miRDB:mmu-miR-466d-3p
  • microrna.org:mmu-miR-466d-3p

References

1. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
2. PMID:17989215 "RNA sequence analysis defines Dicer's role in mouse embryonic stem cells" Calabrese JM, Seila AC, Yeo GW, Sharp PA Proc Natl Acad Sci U S A. 104:18097-18102(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).