Stem-loop sequence mmu-mir-106b

Accession

MI0000407 (change log)

Symbol

MGI:Mir106b

Description

Mus musculus miR-106b stem-loop

Gene family

MIPF0000001; mir-17

Literature search

113 open access papers mention mmu-mir-106b
(733 sentences)

Stem-loop

           ga -ua       g       agaua    uc u 
5' ccugcugg  c   aagugcu acagugc     gugg  c c
   ||||||||  |   ||||||| |||||||     ||||  | u
3' ggacgacc  g   uucaugg ugucacg     cauc  g c
           uc ucg       g       ----c    gu u 

Deep sequencing

438866 reads, 2.77e+03 reads per million, 114 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Comments

Reference [1] reported the same miRNA sequence with two different identifiers - miR-106b and miR-94.

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr5: 138165737-138165818 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000054328 ; Mcm7-002; intron 8

  OTTMUST00000054327 ; Mcm7-001; intron 13

  ENSMUST00000148879 ; Mcm7-002; intron 8

  ENSMUST00000000505 ; Mcm7-001; intron 13

Clustered miRNAs

< 10kb from mmu-mir-106b

• mmu-mir-106b: chr5: 138165737-138165818 [-]
• mmu-mir-93: chr5: 138165523-138165610 [-]
• mmu-mir-25: chr5: 138165321-138165404 [-]

Database links

• EntrezGene:Mir106b
• MGI:Mir106b
• RNAcentral:URS000075A299_10090
• miRBase Tracker:MI0000407

Mature sequence mmu-miR-106b-5p

• Accession: MIMAT0000386
• Previous IDs: mmu-miR-106b
• Sequence: 12 - uaaagugcugacagugcagau - 32
• Deep sequencing: 385406 reads, 107 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00004449AE_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-106b-5p
  • miRDB:mmu-miR-106b-5p
  • microrna.org:mmu-miR-106b-5p

Mature sequence mmu-miR-106b-3p

• Accession: MIMAT0004582
• Previous IDs: mmu-miR-106b*
• Sequence: 52 - ccgcacuguggguacuugcugc - 73
• Deep sequencing: 53322 reads, 104 experiments
• Evidence: experimental; cloned [2], Illumina [3-4]
• Database links:
  • RNAcentral:URS0000384021_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-106b-3p
  • miRDB:mmu-miR-106b-3p
  • microrna.org:mmu-miR-106b-3p

References

1. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).