Stem-loop sequence mmu-mir-183

Accession

MI0000225 (change log)

Symbol

MGI:Mir183

Description

Mus musculus miR-183 stem-loop

Gene family

MIPF0000066; mir-183

Literature search

106 open access papers mention mmu-mir-183
(969 sentences)

Stem-loop

       g      --ac     ga        --   ac 
5' cugu uauggc    uggua  auucacug  uga  a
   |||| ||||||    |||||  ||||||||  |||   
3' gaca auaccg    gccau  uaagugac  acu  g
       a      ggaa     --        ug   cu 

Deep sequencing

546413 reads, 392 reads per million, 101 experiments

Confidence

Annotation confidence: high

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Comments

The mature sequence shown here represents the most commonly cloned form from large-scale cloning studies [3].

Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr6: 30169668-30169737 [-]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from mmu-mir-183

• mmu-mir-183: chr6: 30169668-30169737 [-]
• mmu-mir-96: chr6: 30169446-30169551 [-]
• mmu-mir-182: chr6: 30165918-30165992 [-]

Database links

• EntrezGene:Mir183
• MGI:Mir183
• RNAcentral:URS000075E1B6_10090
• miRBase Tracker:MI0000225

Mature sequence mmu-miR-183-5p

• Accession: MIMAT0000212
• Previous IDs: mmu-miR-183
• Sequence: 6 - uauggcacugguagaauucacu - 27
• Deep sequencing: 541024 reads, 101 experiments
• Evidence: experimental; cloned [1-3], Illumina [4-5]
• Database links:
  • RNAcentral:URS0000528CBC_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-183-5p
  • miRDB:mmu-miR-183-5p
  • microrna.org:mmu-miR-183-5p

Mature sequence mmu-miR-183-3p

• Accession: MIMAT0004539
• Previous IDs: mmu-miR-183*
• Sequence: 45 - gugaauuaccgaagggccauaa - 66
• Deep sequencing: 5377 reads, 80 experiments
• Evidence: experimental; cloned [3], Illumina [4-5]
• Database links:
  • RNAcentral:URS0000345DEB_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-183-3p
  • miRDB:mmu-miR-183-3p
  • microrna.org:mmu-miR-183-3p

References

1. PMID:12554859 "New microRNAs from mouse and human" Lagos-Quintana M, Rauhut R, Meyer J, Borkhardt A, Tuschl T RNA. 9:175-179(2003).
2. PMID:12919684 "Embryonic stem cell-specific MicroRNAs" Houbaviy HB, Murray MF, Sharp PA Dev Cell. 5:351-358(2003).
3. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
4. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
5. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).