Stem-loop sequence rno-mir-376b

Accession

MI0003544 (change log)

Description

Rattus norvegicus miR-376b stem-loop

Gene family

MIPF0000091; mir-368

Literature search

13 open access papers mention rno-mir-376b
(97 sentences)

Stem-loop

   u        u           a     u         cgug  u 
5'  uugguauu aaaagguggau uuccu cuaugguua    cu c
    |||||||| ||||||||||| ||||| |||||||||    ||  
3'  aacuauga uuuuucaccua aagga gauacuaau    gg c
   a        c           c     -         ---a  u 

Deep sequencing

146917 reads, 106 reads per million, 394 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (Rnor_6.0; GCA_000001895.4): chr6: 133873095-133873180 [+]
• Overlapping transcripts:

  intergenic

Clustered miRNAs

< 10kb from rno-mir-376b

• rno-mir-494: chr6: 133864370-133864452 [+]
• rno-mir-679: chr6: 133864564-133864700 [+]
• rno-mir-1193: chr6: 133864698-133864817 [+]
• rno-mir-666: chr6: 133866523-133866621 [+]
• rno-mir-543: chr6: 133866660-133866739 [+]
• rno-mir-495: chr6: 133868288-133868367 [+]
• rno-mir-667: chr6: 133869570-133869661 [+]
• rno-mir-376c: chr6: 133872439-133872522 [+]
• rno-mir-376b: chr6: 133873095-133873180 [+]
• rno-mir-3595: chr6: 133873587-133873706 [-]
• rno-mir-376a: chr6: 133873605-133873686 [+]
• rno-mir-300: chr6: 133874152-133874230 [+]
• rno-mir-381: chr6: 133876615-133876675 [+]
• rno-mir-487b: chr6: 133877124-133877205 [+]
• rno-mir-3576: chr6: 133877812-133877926 [-]
• rno-mir-539: chr6: 133877832-133877907 [+]
• rno-mir-6331: chr6: 133878578-133878700 [+]
• rno-mir-544: chr6: 133879169-133879246 [+]

Database links

• EntrezGene:Mir376b
• miRBase Tracker:MI0003544

Mature sequence rno-miR-376b-5p

• Accession: MIMAT0003195
• Previous IDs: rno-miR-376b*
• Sequence: 16 - guggauauuccuucuaugguua - 37
• Deep sequencing: 30575 reads, 350 experiments
• Evidence: experimental; cloned [2-3], SOLiD [4]
• Predicted targets:
  • TargetScanVert:rno-miR-376b-5p
  • miRDB:rno-miR-376b-5p
  • microrna.org:rno-miR-376b-5p

Mature sequence rno-miR-376b-3p

• Accession: MIMAT0003196
• Previous IDs: rno-miR-376b
• Sequence: 53 - aucauagaggaacauccacuu - 73
• Deep sequencing: 116338 reads, 358 experiments
• Evidence: experimental; cloned [2], SOLiD [4]
• Predicted targets:
  • TargetScanVert:rno-miR-376b-3p
  • miRDB:rno-miR-376b-3p
  • microrna.org:rno-miR-376b-3p

References

1. PMID:16274478 "Identification of clustered microRNAs using an ab initio prediction method" Sewer A, Paul N, Landgraf P, Aravin A, Pfeffer S, Brownstein MJ, Tuschl T, van Nimwegen E, Zavolan M BMC Bioinformatics. 6:267(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:17805466 "Cloning and identification of novel microRNAs from rat hippocampus" He X, Zhang Q, Liu Y, Pan X Acta Biochim Biophys Sin (Shanghai). 39:708-714(2007).
4. PMID:20403161 "Small RNA expression and strain specificity in the rat" Linsen SE, de Wit E, de Bruijn E, Cuppen E BMC Genomics. 11:249(2010).