Stem-loop sequence mmu-mir-378a

Accession

MI0000795 (change log)

Previous IDs

mmu-mir-378

Symbol

MGI:Mir378a

Description

Mus musculus miR-378 stem-loop

Gene family

MIPF0000168; mir-378

Literature search

86 open access papers mention mmu-mir-378a
(863 sentences)

Stem-loop

      g  c              ugu      ccu 
5' agg cu cugacuccaggucc   guguua   c
   ||| || ||||||||||||||   ||||||    
3' ucc ga gacugagguucagg   cacgau   g
      g  a              --u      aaa 

Deep sequencing

12521852 reads, 1.09e+04 reads per million, 107 experiments

Confidence

Annotation confidence: high

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Genome context

• Coordinates (GRCm38; GCA_000001635.2): chr18: 61397835-61397900 [-]
• Overlapping transcripts:

  sense

  OTTMUST00000058693 ; Ppargc1b-001; intron 1

  OTTMUST00000058872 ; Ppargc1b-002; intron 1

  OTTMUST00000059063 ; Ppargc1b-003; intron 1

  ENSMUST00000075299 ; Ppargc1b-001; intron 1

  ENSMUST00000063307 ; Ppargc1b-002; intron 1

  ENSMUST00000142134 ; Ppargc1b-003; intron 1

  antisense

  ENSMUST00000175285 ; Gm25301-201; exon 1

Database links

• EntrezGene:Mirn378
• MGI:Mir378a
• RNAcentral:URS00006E5426_10090
• miRBase Tracker:MI0000795

Mature sequence mmu-miR-378a-5p

• Accession: MIMAT0000742
• Previous IDs: mmu-miR-378;mmu-miR-378*;mmu-miR-378-5p
• Sequence: 5 - cuccugacuccagguccugugu - 26
• Deep sequencing: 7814 reads, 96 experiments
• Evidence: experimental; cloned [1-2], Illumina [3-4]
• Database links:
  • RNAcentral:URS00004BAA8A_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-378a-5p
  • miRDB:mmu-miR-378a-5p
  • microrna.org:mmu-miR-378a-5p

Mature sequence mmu-miR-378a-3p

• Accession: MIMAT0003151
• Previous IDs: mmu-miR-422b;mmu-miR-378;mmu-miR-378-3p
• Sequence: 43 - acuggacuuggagucagaagg - 63
• Deep sequencing: 12514030 reads, 107 experiments
• Evidence: experimental; cloned [2], Illumina [3-4]
• Database links:
  • RNAcentral:URS0000420D03_10090
• Predicted targets:
  • TargetScanVert:mmu-miR-378a-3p
  • miRDB:mmu-miR-378a-3p
  • microrna.org:mmu-miR-378a-3p

References

1. PMID:15538371 "A pancreatic islet-specific microRNA regulates insulin secretion" Poy MN, Eliasson L, Krutzfeldt J, Kuwajima S, Ma X, Macdonald PE, Pfeffer S, Tuschl T, Rajewsky N, Rorsman P, Stoffel M Nature. 432:226-230(2004).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).
3. PMID:20215419 "MicroRNA transcriptome in the newborn mouse ovaries determined by massive parallel sequencing" Ahn HW, Morin RD, Zhao H, Harris RA, Coarfa C, Chen ZJ, Milosavljevic A, Marra MA, Rajkovic A Mol Hum Reprod. 16:463-471(2010).
4. PMID:20413612 "Mammalian microRNAs: experimental evaluation of novel and previously annotated genes" Chiang HR, Schoenfeld LW, Ruby JG, Auyeung VC, Spies N, Baek D, Johnston WK, Russ C, Luo S, Babiarz JE, Blelloch R, Schroth GP, Nusbaum C, Bartel DP Genes Dev. 24:992-1009(2010).