Stem-loop sequence hsa-mir-500a

Accession

MI0003184 (change log)

Previous IDs

hsa-mir-500

Symbol

HGNC:MIR500A

Description

Homo sapiens miR-500a stem-loop

Gene family

MIPF0000139; mir-500

Literature search

33 open access papers mention hsa-mir-500a
(230 sentences)

Stem-loop

       c c     -u         uac ug    agag   ugu 
5' gcuc c cucuc  aauccuugc   c  ggug    ugc   c
   |||| | |||||  |||||||||   |  ||||    |||   u
3' cgag g gagag  uuaggaacg   g  ccac    acg   g
       a c     uc         --- gu    -gua   uaa 

Deep sequencing

72349 reads, 63.1 reads per million, 157 experiments

Confidence

Annotation confidence: high

Feedback: Do you believe this miRNA is real?

Genome context

• Coordinates (GRCh38; GCA_000001405.15): chrX: 50008431-50008514 [+]
• Overlapping transcripts:

  sense

  OTTHUMT00000056562 ; CCNB3-005; intron 1

  OTTHUMT00000056558 ; CCNB3-001; intron 1

  OTTHUMT00000056559 ; CCNB3-002; intron 1

  OTTHUMT00000056560 ; CCNB3-003; intron 1

  OTTHUMT00000056561 ; CCNB3-004; intron 2

  ENST00000491907 ; CCNB3-005; intron 1

  ENST00000376042 ; CCNB3-001; intron 1

  ENST00000376038 ; CCNB3-002; intron 1

  ENST00000476167 ; CCNB3-003; intron 1

  ENST00000493507 ; CCNB3-004; intron 2

Clustered miRNAs

< 10kb from hsa-mir-500a

• hsa-mir-532: chrX: 50003148-50003238 [+]
• hsa-mir-188: chrX: 50003503-50003588 [+]
• hsa-mir-500a: chrX: 50008431-50008514 [+]
• hsa-mir-362: chrX: 50008964-50009028 [+]
• hsa-mir-501: chrX: 50009722-50009805 [+]
• hsa-mir-500b: chrX: 50010672-50010750 [+]
• hsa-mir-660: chrX: 50013241-50013337 [+]
• hsa-mir-502: chrX: 50014598-50014683 [+]

Database links

• EntrezGene:MIR500
• HGNC:MIR500A
• RNAcentral:URS000075E243_9606
• miRBase Tracker:MI0003184

Mature sequence hsa-miR-500a-5p

• Accession: MIMAT0004773
• Previous IDs: hsa-miR-500;hsa-miR-500a
• Sequence: 13 - uaauccuugcuaccugggugaga - 35
• Deep sequencing: 14661 reads, 149 experiments
• Evidence: experimental; cloned [2]
• Database links:
  • RNAcentral:URS000039A052_9606
• Predicted targets:
  • TargetMiner:hsa-miR-500a-5p
  • TargetScanVert:hsa-miR-500a-5p
  • miRDB:hsa-miR-500a-5p
  • microrna.org:hsa-miR-500a-5p

Mature sequence hsa-miR-500a-3p

• Accession: MIMAT0002871
• Previous IDs: hsa-miR-500;hsa-miR-500*;hsa-miR-500a*
• Sequence: 52 - augcaccugggcaaggauucug - 73
• Deep sequencing: 57680 reads, 157 experiments
• Evidence: experimental; array-cloned [1], cloned [2]
• Database links:
  • RNAcentral:URS00003F659E_9606
• Predicted targets:
  • TargetMiner:hsa-miR-500a-3p
  • TargetScanVert:hsa-miR-500a-3p
  • miRDB:hsa-miR-500a-3p
  • microrna.org:hsa-miR-500a-3p

References

1. PMID:15965474 "Identification of hundreds of conserved and nonconserved human microRNAs" Bentwich I, Avniel A, Karov Y, Aharonov R, Gilad S, Barad O, Barzilai A, Einat P, Einav U, Meiri E, Sharon E, Spector Y, Bentwich Z Nat Genet. 37:766-770(2005).
2. PMID:17604727 "A mammalian microRNA expression atlas based on small RNA library sequencing" Landgraf P, Rusu M, Sheridan R, Sewer A, Iovino N, Aravin A, Pfeffer S, Rice A, Kamphorst AO, Landthaler M, Lin C, Socci ND, Hermida L, Fulci V, Chiaretti S, Foa R, Schliwka J, Fuchs U, Novosel A, Muller RU, Schermer B, Bissels U, Inman J, Phan Q, Chien M Cell. 129:1401-1414(2007).